HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage
Published 2011 View Full Article
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Title
HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage
Authors
Keywords
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Journal
ONCOGENE
Volume 30, Issue 48, Pages 4802-4813
Publisher
Springer Nature
Online
2011-05-23
DOI
10.1038/onc.2011.182
References
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Related references
Note: Only part of the references are listed.- ATM kinase is a master switch for the ΔNp63α phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage
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- Phospho-ΔNp63α/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure
- (2010) Yiping Huang et al. CELL CYCLE
- Cables1 protects p63 from proteasomal degradation to ensure deletion of cells after genotoxic stress
- (2010) Ning Wang et al. EMBO REPORTS
- MDM2 and Fbw7 cooperate to induce p63 protein degradation following DNA damage and cell differentiation
- (2010) F. Galli et al. JOURNAL OF CELL SCIENCE
- Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells
- (2010) R Puca et al. ONCOGENE
- Negative Regulation of 4 Integrin Transcription by Homeodomain-Interacting Protein Kinase 2 and p53 Impairs Tumor Progression
- (2009) G. Bon et al. CANCER RESEARCH
- Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis
- (2009) Giorgia Bracaglia et al. EMBO REPORTS
- Axin determines cell fate by controlling the p53 activation threshold after DNA damage
- (2009) Qinxi Li et al. NATURE CELL BIOLOGY
- Inhibition of the c-Abl–TAp63 pathway protects mouse oocytes from chemotherapy-induced death
- (2009) Stefania Gonfloni et al. NATURE MEDICINE
- The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4
- (2009) D Yamada et al. ONCOGENE
- PEBP2- /CBF- -dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis
- (2008) H.-J. Wee et al. BLOOD
- Reversible Dysfunction of Wild-Type p53 following Homeodomain-Interacting Protein Kinase-2 Knockdown
- (2008) R. Puca et al. CANCER RESEARCH
- WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis
- (2008) Y Li et al. CELL DEATH AND DIFFERENTIATION
- Therapeutic prospects for p73 and p63: Rising from the shadow of p53
- (2008) Anna Vilgelm et al. DRUG RESISTANCE UPDATES
- Phosphorylation and Stabilization of TAp63γ by IκB Kinase-β
- (2008) Mary MacPartlin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR
- (2008) Melanie Winter et al. NATURE CELL BIOLOGY
- PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage
- (2008) E Gresko et al. ONCOGENE
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