Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15

Abstract PR-10: RNAi-directed identification of chemosensitizers of GSK923295 response

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DNA Damage in Oocytes Induces a Switch of the Quality Control Factor TAp63α from Dimer to Tetramer

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p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53

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ΔNp63α Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis

(2011) William M. Keyes et al.   Cell Stem Cell

Caspase-2-Mediated Cleavage of Mdm2 Creates a p53-Induced Positive Feedback Loop

(2011) Trudy G. Oliver et al.   MOLECULAR CELL

The p53 family: guardians of maternal reproduction

(2011) Arnold J. Levine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The E3 ubiquitin ligase WWP1 regulates ΔNp63-dependent transcription through Lys63 linkages

(2010) Angelo Peschiaroli et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ISG15 and immune diseases

(2010) Young Joo Jeon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

RETRACTED: DNA-PKcs-PIDDosome: A Nuclear Caspase-2-Activating Complex with Role in G2/M Checkpoint Maintenance

(2009) Mingan Shi et al.   CELL

ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway

(2009) Young Joo Jeon et al.   EMBO REPORTS

TAp63 induces senescence and suppresses tumorigenesis in vivo

(2009) Xuecui Guo et al.   NATURE CELL BIOLOGY

A tumor suppressor function for caspase-2

(2009) L. H. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis

(2008) Y Li et al.   CELL DEATH AND DIFFERENTIATION

miR-203 represses ‘stemness’ by repressing ΔNp63

(2008) A M Lena et al.   CELL DEATH AND DIFFERENTIATION

UBE1L causes lung cancer growth suppression by targeting cyclin D1

(2008) Q. Feng et al.   MOLECULAR CANCER THERAPEUTICS

ISG15 as a novel tumor biomarker for drug sensitivity

(2008) Shyamal D. Desai et al.   MOLECULAR CANCER THERAPEUTICS

UBE1L represses PML/RAR  by targeting the PML domain for ISG15ylation

(2008) S. J. Shah et al.   MOLECULAR CANCER THERAPEUTICS

A skin microRNA promotes differentiation by repressing ‘stemness’

(2008) Rui Yi et al.   NATURE