Secreting-lux/pT-ClyA engineered bacteria suppresses tumor growth via interleukin-1β in two pathways

Bacterial microbots for acid-labile release of hybrid micelles to promote the synergistic antitumor efficacy

(2018) Songzhi Xie et al.   Acta Biomaterialia

Therapeutic advantage of genetically engineered Salmonella typhimurium carrying short hairpin RNA against inhibin alpha subunit in cancer treatment

(2018) W Yoon et al.   ANNALS OF ONCOLOGY

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

TLR7 agonist in combination with Salmonella as an effective antimelanoma immunotherapy

(2018) Magdalena Vola et al.   Immunotherapy

Intestinal lamina propria CD4+T cells promote bactericidal activity of macrophages via galectin-9 and Tim-3 interaction during Salmonella typhimurium infection

(2018) Xin Yu et al.   INFECTION AND IMMUNITY

Structure-Function Relationships of the Neisserial EptA Enzyme Responsible for Phosphoethanolamine Decoration of Lipid A: Rationale for Drug Targeting

(2018) Charlene M. Kahler et al.   Frontiers in Microbiology

Delayed oseltamivir plus sirolimus treatment attenuates H1N1 virus-induced severe lung injury correlated with repressed NLRP3 inflammasome activation and inflammatory cell infiltration

(2018) Xuehong Jia et al.   PLoS Pathogens

The critical role of toll-like receptors — From microbial recognition to autoimmunity: A comprehensive review

(2016) Maximiliano Javier Jiménez-Dalmaroni et al.   AUTOIMMUNITY REVIEWS

MDA7 combined with targeted attenuated Salmonella vector SL7207/pBud-VP3 inhibited growth of gastric cancer cells

(2016) Hongdan Cao et al.   BIOMEDICINE & PHARMACOTHERAPY

The immunobiology of Campylobacter jejuni: Innate immunity and autoimmune diseases

(2016) Vongsavanh Phongsisay   IMMUNOBIOLOGY

Bacteria-Mediated Hypoxia-Specific Delivery of Nanoparticles for Tumors Imaging and Therapy

(2016) Cheng-Hung Luo et al.   NANO LETTERS

RGD Peptide Cell-Surface Display Enhances the Targeting and Therapeutic Efficacy of Attenuated Salmonella-mediated Cancer Therapy

(2016) Seung-Hwan Park et al.   Theranostics

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

(2015) Eva M. Palsson-McDermott et al.   Cell Metabolism

Activation of inflammasome by attenuatedSalmonella typhimuriumin bacteria-mediated cancer therapy

(2015) Thuy Xuan Phan et al.   MICROBIOLOGY AND IMMUNOLOGY

Efficiency of Conditionally Attenuated Salmonella enterica Serovar Typhimurium in Bacterium-Mediated Tumor Therapy

(2015) Michael Frahm et al.   mBio

Salmonella typhimurium Suppresses Tumor Growth via the Pro-Inflammatory Cytokine Interleukin-1β

(2015) Jung-Eun Kim et al.   Theranostics

RNA and β-Hemolysin of Group BStreptococcusInduce Interleukin-1β (IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages

(2014) Rahul Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering of Bacteria for the Visualization of Targeted Delivery of a Cytolytic Anticancer Agent

(2013) Sheng-Nan Jiang et al.   MOLECULAR THERAPY

Effect of ultrasound irradiation on bacterial internalization and bacteria-mediated gene transfer to cancer cells

(2013) Kazuaki Ninomiya et al.   ULTRASONICS SONOCHEMISTRY

Roles of toll-like receptors in Cancer: A double-edged sword for defense and offense

(2012) Shaherin Basith et al.   ARCHIVES OF PHARMACAL RESEARCH

Genetic variation and alterations of genes involved in NFκB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer

(2012) Jonas Ungerbäck et al.   CARCINOGENESIS

Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma

(2012) Lih-Chyang Chen et al.   EMBO Molecular Medicine

Therapeutic live vaccines as a potential anticancer strategy

(2012) Azam Bolhassani et al.   INTERNATIONAL JOURNAL OF CANCER

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Phosphorylation of NLRC4 is critical for inflammasome activation

(2012) Yan Qu et al.   NATURE

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

(2012) Mélanie Bruchard et al.   NATURE MEDICINE

Expression and Functional Research of TLR4 in Human Colon Carcinoma

(2010) Xiao-Yan Tang et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

A Novel Listeria monocytogenes-Based DNA Delivery System for Cancer Gene Therapy

(2010) Jan Peter van Pijkeren et al.   HUMAN GENE THERAPY

Inhibition of Tumor Growth and Metastasis by a Combination of Escherichia coli –mediated Cytolytic Therapy and Radiotherapy

(2010) Sheng-Nan Jiang et al.   MOLECULAR THERAPY

Improved mycobacterial tetracycline inducible vectors

(2010) Kerstin J. Williams et al.   PLASMID

Caspase 1–independent activation of interleukin-1β in neutrophil-predominant inflammation

(2009) Monica Guma et al.   ARTHRITIS AND RHEUMATISM

Genetically Engineered Salmonella typhimurium as an Imageable Therapeutic Probe for Cancer

(2009) V. H. Nguyen et al.   CANCER RESEARCH

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD

Characterization of HCT116 Human Colon Cancer Cells in an Orthotopic Model

(2007) Ashwani Rajput et al.   JOURNAL OF SURGICAL RESEARCH