RNA and β-Hemolysin of Group BStreptococcusInduce Interleukin-1β (IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages

The DHX33 RNA Helicase Senses Cytosolic RNA and Activates the NLRP3 Inflammasome

(2013) Hiroki Mitoma et al.   IMMUNITY

A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta

(2013) Christopher Whidbey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of the NLRP3 Inflammasome by Group B Streptococci

(2012) A. Costa et al.   JOURNAL OF IMMUNOLOGY

Bacterial RNA Mediates Activation of Caspase-1 and IL-1  Release Independently of TLRs 3, 7, 9 and TRIF but Is Dependent on UNC93B

(2012) T. Eigenbrod et al.   JOURNAL OF IMMUNOLOGY

Innate Immune Sensing of DNA

(2011) Shruti Sharma et al.   PLoS Pathogens

Macrophages recognize streptococci through bacterial single-stranded RNA

(2010) Sachin D Deshmukh et al.   EMBO REPORTS

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

(2010) T. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

TLR-Independent Type I Interferon Induction in Response to an Extracellular Bacterial Pathogen via Intracellular Recognition of Its DNA

(2008) Marie Charrel-Dennis et al.   Cell Host & Microbe

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY