The 5-Hydroxymethylcytosine (5hmC) Reader UHRF2 Is Required for Normal Levels of 5hmC in Mouse Adult Brain and Spatial Learning and Memory

Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer

(2016) Yuanhui Jia et al.   Cell Discovery

Mechanism and Function of Oxidative Reversal of DNA and RNA Methylation

(2014) Li Shen et al.   Annual Review of Biochemistry

Differential Regulation of the Ten-Eleven Translocation (TET) Family of Dioxygenases byO-Linked β-N-Acetylglucosamine Transferase (OGT)

(2014) Qiao Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2

(2014) Ting Zhou et al.   MOLECULAR CELL

5-Hydroxymethylcytosine is a predominantly stable DNA modification

(2014) Martin Bachman et al.   Nature Chemistry

DNA Methylation in Mammals

(2014) E. Li et al.   Cold Spring Harbor Perspectives in Biology

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

(2013) Cornelia G. Spruijt et al.   CELL

Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition

(2013) Run-Rui Zhang et al.   Cell Stem Cell

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

(2013) Rachel Deplus et al.   EMBO JOURNAL

Ten-Eleven Translocation 1 (Tet1) Is Regulated byO-LinkedN-Acetylglucosamine Transferase (Ogt) for Target Gene Repression in Mouse Embryonic Stem Cells

(2013) Feng-Tao Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tet Proteins Connect the O-Linked N-acetylglucosamine Transferase Ogt to Chromatin in Embryonic Stem Cells

(2013) Pietro Vella et al.   MOLECULAR CELL

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system

(2013) Dali Li et al.   NATURE BIOTECHNOLOGY

TET1 Controls CNS 5-Methylcytosine Hydroxylation, Active DNA Demethylation, Gene Transcription, and Memory Formation

(2013) Garrett A. Kaas et al.   NEURON

Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction

(2013) Andrii Rudenko et al.   NEURON

Global Epigenomic Reconfiguration During Mammalian Brain Development

(2013) R. Lister et al.   SCIENCE

UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9

(2013) Xiaoli Liu et al.   Nature Communications

MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System

(2012) Marian Mellén et al.   CELL

Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome

(2012) Miao Yu et al.   CELL

NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape

(2012) Tsutomu Mori et al.   FEBS LETTERS

TET2 promotes histone O-GlcNAcylation during gene transcription

(2012) Qiang Chen et al.   NATURE

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution

(2012) M. J. Booth et al.   SCIENCE

S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance

(2011) Jiqin Zhang et al.   CELL RESEARCH

Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways

(2011) Garwin Pichler et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

(2011) Y.-F. He et al.   SCIENCE

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

DNA methylation and memory formation

(2010) Jeremy J Day et al.   NATURE NEUROSCIENCE

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

(2010) Jian Feng et al.   NATURE NEUROSCIENCE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Amygdala infusions of an NR2B-selective or an NR2A-preferring NMDA receptor antagonist differentially influence fear conditioning and expression in the fear-potentiated startle test

(2008) D. L. Walker et al.   LEARNING & MEMORY

The PHD Domain of Np95 (mUHRF1) Is Involved in Large-Scale Reorganization of Pericentromeric Heterochromatin

(2008) Roberto Papait et al.   MOLECULAR BIOLOGY OF THE CELL