The Golgi-Associated Plant Pathogenesis-Related Protein GAPR-1 Enhances Type I Interferon Signaling Pathway in Response to Toll-Like Receptor 4

Golgi-Associated plant Pathogenesis Related protein 1 (GAPR-1) forms amyloid-like fibrils by interaction with acidic phospholipids and inhibits Aβ aggregation

(2014) Nick K. Olrichs et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

GLIPR-2 Overexpression in HK-2 Cells Promotes Cell EMT and Migration through ERK1/2 Activation

(2013) Shaoguang Huang et al.   PLoS One

Hypoxia Promotes Epithelial - Mesenchymal Transition of Hepatocellular Carcinoma Cells via Inducing GLIPR-2 Expression

(2013) Shao-guang Huang et al.   PLoS One

Interaction of GAPR-1 with lipid bilayers is regulated by alternative homodimerization

(2012) Josse van Galen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Balancing pro- and anti-inflammatory TLR4 signaling

(2012) Sabine Siegemund et al.   NATURE IMMUNOLOGY

The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock

(2012) Ezra Aksoy et al.   NATURE IMMUNOLOGY

Defining the subcellular sites of innate immune signal transduction

(2012) Jonathan C. Kagan   TRENDS IN IMMUNOLOGY

The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation

(2012) Sarah L. Doyle et al.   Nature Communications

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway

(2009) Eva M Palsson-McDermott et al.   NATURE IMMUNOLOGY

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1

(2008) Huazhang An et al.   NATURE IMMUNOLOGY

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY

IRAK1: A critical signaling mediator of innate immunity

(2007) Sridevi Gottipati et al.   CELLULAR SIGNALLING