Celiac Disease and the Microbiome

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1−/Δ7 mice

(2019) Benthe van der Lugt et al.   Immunity & Ageing

Comparison of Small Gut and Whole Gut Microbiota of First-Degree Relatives With Adult Celiac Disease Patients and Controls

(2019) Rahul Bodkhe et al.   Frontiers in Microbiology

Association Between Antibiotics in the First Year of Life and Celiac Disease

(2019) Stine Dydensborg Sander et al.   GASTROENTEROLOGY

Lactobacilli Degrade Wheat Amylase Trypsin Inhibitors to Reduce Intestinal Dysfunction Induced by Immunogenic Wheat Proteins

(2019) Alberto Caminero et al.   GASTROENTEROLOGY

Association between early life (prenatal and postnatal) antibiotic administration and coeliac disease: a systematic review

(2019) Maciej Kołodziej et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Orally administered Lactobacillus casei exhibited several probiotic properties in artificially suckling rabbits

(2019) Xuemei Shen et al.   ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES

Celiac disease‐associated Neisseria flavescens decreases mitochondrial respiration in CaCo‐2 epithelial cells: Impact of Lactobacillus paracasei CBA L74 on bacterial‐induced cellular imbalance

(2019) Giuseppe Labruna et al.   CELLULAR MICROBIOLOGY

Breaking Down Barriers: How Understanding Celiac Disease Pathogenesis Informed the Development of Novel Treatments

(2019) Francesco Valitutti et al.   DIGESTIVE DISEASES AND SCIENCES

Increased Prevalence of Celiac Disease in School-age Children in Italy

(2019) Simona Gatti et al.   Clinical Gastroenterology and Hepatology

Gut Microbiota and Colonization Resistance against Bacterial Enteric Infection

(2019) Q. R. Ducarmon et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Human Milk Oligosaccharides Protect against Necrotizing Enterocolitis by Inhibiting Intestinal Damage via Increasing the Proliferation of Crypt Cells

(2019) Chenyuan Wang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Concise Review: Metabolism and Gut Microbiota in Cancer Immunoediting, CD8/Treg Ratios, Immune Cell Homeostasis, and Cancer (Immuno)Therapy

(2019) Irina Kareva   STEM CELLS

Methods and basic concepts for microbiota assessment

(2019) Marcio Costa et al.   VETERINARY JOURNAL

Gut Microbiome: Profound Implications for Diet and Disease

(2019) Ronald D. Hills et al.   Nutrients

Human gut derived-organoids provide model to study gluten response and effects of microbiota-derived molecules in celiac disease

(2019) Rachel Freire et al.   Scientific Reports

The potential probiotic Lactobacillus rhamnosus CNCM I-3690 strain protects the intestinal barrier by stimulating both mucus production and cytoprotective response

(2019) Rebeca Martín et al.   Scientific Reports

C. difficile and celiac disease: the “difficile” to tell association

(2018) Francesco Valitutti et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis

(2018) Prashant Singh et al.   Clinical Gastroenterology and Hepatology

Metagenomics, culturomics, and the human gut microbiota

(2018) Sophie Amrane et al.   Expert Review of Anti-Infective Therapy

Meconium microbiome as a new source of information about long-term health and disease: questions and answers

(2018) Paulina Wilczyńska et al.   Journal of Maternal-Fetal & Neonatal Medicine

Current understanding of the human microbiome

(2018) Jack A Gilbert et al.   NATURE MEDICINE

Early fecal microbiota composition in children who later develop celiac disease and associated autoimmunity

(2018) Anniina Rintala et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Is an enzyme supplement for celiac disease finally on the cards?

(2018) Julia König et al.   Expert Review of Gastroenterology & Hepatology

Gut microbiota trajectory in early life may predict development of celiac disease

(2018) Marta Olivares et al.   Microbiome

Gut microbiota and IBD: causation or correlation?

(2017) Josephine Ni et al.   Nature Reviews Gastroenterology & Hepatology

Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease

(2017) Romain Bouziat et al.   SCIENCE

Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity

(2017) Kaisa M. Kemppainen et al.   JAMA Pediatrics

Metagenomics Reveals Dysbiosis and a Potentially Pathogenic N. flavescens Strain in Duodenum of Adult Celiac Patients

(2016) Valeria D'Argenio et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

No Change in the Mucosal Gut Microbiome is Associated With Celiac Disease-Specific Microbiome Alteration in Adult Patients

(2016) Valeria D'Argenio et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life: a systematic review

(2016) Erigene Rutayisire et al.   BMC GASTROENTEROLOGY

Screening for Type 1 Diabetes–, Thyroid-, Gastric-, and Adrenal-Specific Humoral Autoimmunity in 529 Children and Adolescents With Celiac Disease at Diagnosis Identifies as Positive One in Every Nine Patients

(2016) Claudio Tiberti et al.   DIABETES CARE

Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity

(2016) Alberto Caminero et al.   GASTROENTEROLOGY

Study of duodenal bacterial communities by 16S rRNA gene analysis in adults with active celiac diseasevsnon-celiac disease controls

(2016) E. Nistal et al.   JOURNAL OF APPLIED MICROBIOLOGY

Bifidobacterium infantis NLS Super Strain Reduces the Expression of α-Defensin-5, a Marker of Innate Immunity, in the Mucosa of Active Celiac Disease Patients

(2016) Maria I. Pinto-Sánchez et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases

(2016) Mingming Sun et al.   JOURNAL OF GASTROENTEROLOGY

Identification of Oligosaccharides in Human Milk Bound onto the Toxin A Carbohydrate Binding Site of Clostridium difficile

(2016) Thi Thanh Hanh Nguyen et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

The intestinal epithelial barrier: a therapeutic target?

(2016) Matthew A. Odenwald et al.   Nature Reviews Gastroenterology & Hepatology

The microbiome as a possible target to prevent celiac disease

(2016) Maureen M. Leonard et al.   Expert Review of Gastroenterology & Hepatology

Are ESPGHAN “Biopsy-Sparing” Guidelines for Celiac Disease also Suitable for Asymptomatic Patients?

(2015) Chiara Maria Trovato et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Infections and Risk of Celiac Disease in Childhood: A Prospective Nationwide Cohort Study

(2015) Karl Mårild et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Intestinal Microbiota Modulates Gluten-Induced Immunopathology in Humanized Mice

(2015) Heather J. Galipeau et al.   AMERICAN JOURNAL OF PATHOLOGY

Perinatal Risk Factors for Development of Celiac Disease in Children, Based on the Prospective Norwegian Mother and Child Cohort Study

(2015) Louise Emilsson et al.   Clinical Gastroenterology and Hepatology

World Perspective and Celiac Disease Epidemiology

(2015) Carlo Catassi et al.   DIGESTIVE DISEASES

Gluten-free diet or alternative therapy: a survey on what parents of celiac children want

(2015) Lorenzo Norsa et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Progress and Challenges in Developing Metabolic Footprints from Diet in Human Gut Microbial Cometabolism

(2015) Linda C Duffy et al.   JOURNAL OF NUTRITION

Celiac Disease Genomic, Environmental, Microbiome, and Metabolomic (CDGEMM) Study Design: Approach to the Future of Personalized Prevention of Celiac Disease

(2015) Maureen Leonard et al.   Nutrients

Humoral Immunity Links Candida albicans Infection and Celiac Disease

(2015) Marion Corouge et al.   PLoS One

Association of Maternal Education, Early Infections, and Antibiotic Use With Celiac Disease: A Population-Based Birth Cohort Study in Northeastern Italy

(2014) C. Canova et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Antibiotic exposure in pregnancy and risk of coeliac disease in offspring: a cohort study

(2014) Karl Mårild et al.   BMC GASTROENTEROLOGY

The composition of the gut microbiota shapes the colon mucus barrier

(2014) H. E. Jakobsson et al.   EMBO REPORTS

The HLA-DQ2 genotype selects for early intestinal microbiota composition in infants at high risk of developing coeliac disease

(2014) M Olivares et al.   GUT

Introduction of Gluten, HLA Status, and the Risk of Celiac Disease in Children

(2014) Elena Lionetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Randomized Feeding Intervention in Infants at High Risk for Celiac Disease

(2014) Sabine L. Vriezinga et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Placenta Harbors a Unique Microbiome

(2014) K. Aagaard et al.   Science Translational Medicine

Duodenal-Mucosal Bacteria Associated with Celiac Disease in Children

(2013) Ester Sánchez et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antibiotic exposure and the development of coeliac disease: a nationwide case–control study

(2013) Karl Mårild et al.   BMC GASTROENTEROLOGY

Duodenal microbiota composition and mucosal homeostasis in pediatric celiac disease

(2013) Jing Cheng et al.   BMC GASTROENTEROLOGY

Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months

(2013) M. B. Azad et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

The cultivable human oral gluten-degrading microbiome and its potential implications in coeliac disease and gluten sensitivity

(2013) M. Fernandez-Feo et al.   CLINICAL MICROBIOLOGY AND INFECTION

Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by Caesarean section

(2013) Hedvig E Jakobsson et al.   GUT

The Duodenal Microbiota Composition of Adult Celiac Disease Patients Is Associated with the Clinical Manifestation of the Disease

(2013) Pirjo Wacklin et al.   INFLAMMATORY BOWEL DISEASES

Prevalence of Childhood Celiac Disease and Changes in Infant Feeding

(2013) A. Ivarsson et al.   PEDIATRICS

Intestinal T-cell Responses in Celiac Disease – Impact of Celiac Disease Associated Bacteria

(2013) Veronika Sjöberg et al.   PLoS One

Composition and diversity of the duodenal mucosa-associated microbiome in children with untreated coeliac disease

(2013) Tim G.J. de Meij et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Dietary Inhibitors of Histone Deacetylases in Intestinal Immunity and Homeostasis

(2013) R. Schilderink et al.   Frontiers in Immunology

Discerning the Role of Bacteroides fragilis in Celiac Disease Pathogenesis

(2012) E. Sánchez et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Differences in faecal bacteria populations and faecal bacteria metabolism in healthy adults and celiac disease patients

(2012) Esther Nistal et al.   BIOCHIMIE

Early infections are associated with increased risk for celiac disease: an incident case-referent study

(2012) Anna Myléus et al.   BMC Pediatrics

IntestinalStaphylococcus spp.and virulent features associated with coeliac disease

(2012) Ester Sánchez et al.   JOURNAL OF CLINICAL PATHOLOGY

Modulation of phenotypic and functional maturation of dendritic cells by intestinal bacteria and gliadin: relevance for celiac disease

(2012) G. De Palma et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Gluten induces coeliac-like disease in sensitised mice involving IgA, CD71 and transglutaminase 2 interactions that are prevented by probiotics

(2012) Christina Papista et al.   LABORATORY INVESTIGATION

Size and dynamics of mucosal and peripheral IL-17A+ T-cell pools in pediatric age and their disturbance in celiac disease

(2012) R La Scaleia et al.   Mucosal Immunology

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

Influence of Milk-Feeding Type and Genetic Risk of Developing Coeliac Disease on Intestinal Microbiota of Infants: The PROFICEL Study

(2012) Giada De Palma et al.   PLoS One

Bifidobacterium longum CECT 7347 Modulates Immune Responses in a Gliadin-Induced Enteropathy Animal Model

(2012) José Moisés Laparra et al.   PLoS One

Proof of Concept of Microbiome-Metabolome Analysis and Delayed Gluten Exposure on Celiac Disease Autoimmunity in Genetically At-Risk Infants

(2012) Maria Sellitto et al.   PLoS One

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Influence of Environmental and Genetic Factors Linked to Celiac Disease Risk on Infant Gut Colonization by Bacteroides Species

(2011) Ester Sánchez et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Pregnancy Outcome and Risk of Celiac Disease in Offspring: A Nationwide Case-Control Study

(2011) Karl Mårild et al.   GASTROENTEROLOGY

Differences of small intestinal bacteria populations in adults and children with/without celiac disease: Effect of age, gluten diet, and disease

(2011) Esther Nistal et al.   INFLAMMATORY BOWEL DISEASES

Physiology of Consumption of Human Milk Oligosaccharides by Infant Gut-associated Bifidobacteria

(2011) Sadaki Asakuma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of Microbiota, Toll-like Receptors, and Their Regulators in the Small Intestinal Mucosa in Celiac Disease

(2011) Marko Kalliomäki et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Bifidobacteria can protect from enteropathogenic infection through production of acetate

(2011) Shinji Fukuda et al.   NATURE

Immunomodulatory Effects of Lactobacillus casei Administration in a Mouse Model of Gliadin-Sensitive Enteropathy

(2011) R. D’Arienzo et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

The Antibacterial Lectin RegIII  Promotes the Spatial Segregation of Microbiota and Host in the Intestine

(2011) S. Vaishnava et al.   SCIENCE

Natural history of celiac disease autoimmunity in a USA cohort followed since 1974

(2010) Carlo Catassi et al.   ANNALS OF MEDICINE

A distinctive 'microbial signature' in celiac pediatric patients

(2010) Serena Schippa et al.   BMC MICROBIOLOGY

Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children

(2010) Giada De Palma et al.   BMC MICROBIOLOGY

Live probiotic Bifidobacterium lactis bacteria inhibit the toxic effects induced by wheat gliadin in epithelial cell culture

(2010) K. Lindfors et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Bifidobacteria inhibit the inflammatory response induced by gliadins in intestinal epithelial cells via modifications of toxic peptide generation during digestion

(2010) J.M. Laparra et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Intestinal Microbiota of 6-week-old Infants Across Europe: Geographic Influence Beyond Delivery Mode, Breast-feeding, and Antibiotics

(2010) Matteo Fallani et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Cesarean Delivery Is Associated With Celiac Disease but Not Inflammatory Bowel Disease in Children

(2010) E. Decker et al.   PEDIATRICS

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proximal Small Intestinal Microbiota and Identification of Rod-Shaped Bacteria Associated With Childhood Celiac Disease

(2009) Gangwei Ou et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Modulation of the immune response by probiotic strains in a mouse model of gluten sensitivity

(2009) Rossana D’Arienzo et al.   CYTOKINE

Reduced diversity and increased virulence-gene carriage in intestinal enterobacteria of coeliac children

(2008) Ester Sánchez et al.   BMC GASTROENTEROLOGY

Specific duodenal and faecal bacterial groups associated with paediatric coeliac disease

(2008) M C Collado et al.   JOURNAL OF CLINICAL PATHOLOGY

Bifidobacterium strains suppress in vitro the pro-inflammatory milieu triggered by the large intestinal microbiota of coeliac patients

(2008) Marcela Medina et al.   Journal of Inflammation-London