Is an enzyme supplement for celiac disease finally on the cards?

A randomised, double-blind, cross-over trial to evaluate bread, in which gluten has been pre-digested by prolyl endoprotease treatment, in subjects self-reporting benefits of adopting a gluten-free or low-gluten diet

(2018) Dinka Rees et al.   BRITISH JOURNAL OF NUTRITION

Fructan, Rather Than Gluten, Induces Symptoms in Patients With Self-Reported Non-Celiac Gluten Sensitivity

(2018) Gry I. Skodje et al.   GASTROENTEROLOGY

No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease

(2017) Joseph A. Murray et al.   GASTROENTEROLOGY

Randomized clinical trial: Effective gluten degradation by Aspergillus niger-derived enzyme in a complex meal setting

(2017) Julia König et al.   Scientific Reports

Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of coeliac disease

(2016) Melanie Uhde et al.   GUT

Randomised clinical study:Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers

(2015) B. N. Salden et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Adverse Effects of Wheat Gluten

(2015) Frits Koning   ANNALS OF NUTRITION AND METABOLISM

Small Amounts of Gluten in Subjects With Suspected Nonceliac Gluten Sensitivity: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial

(2015) Antonio Di Sabatino et al.   Clinical Gastroenterology and Hepatology

Influence of dietary components on Aspergillus niger prolyl endoprotease mediated gluten degradation

(2015) Veronica Montserrat et al.   FOOD CHEMISTRY

Nonceliac Gluten Sensitivity

(2015) Alessio Fasano et al.   GASTROENTEROLOGY

Engineering of Kuma030: A Gliadin Peptidase That Rapidly Degrades Immunogenic Gliadin Peptides in Gastric Conditions

(2015) Clancey Wolf et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ineffective Degradation of Immunogenic Gluten Epitopes by Currently Available Digestive Enzyme Supplements

(2015) George Janssen et al.   PLoS One

Glutenase ALV003 Attenuates Gluten-Induced Mucosal Injury in Patients With Celiac Disease

(2014) Marja-Leena Lähdeaho et al.   GASTROENTEROLOGY

Diets that differ in their FODMAP content alter the colonic luminal microenvironment

(2014) Emma P Halmos et al.   GUT

No Effects of Gluten in Patients With Self-Reported Non-Celiac Gluten Sensitivity After Dietary Reduction of Fermentable, Poorly Absorbed, Short-Chain Carbohydrates

(2013) Jessica R. Biesiekierski et al.   GASTROENTEROLOGY

Consumption of gluten with gluten-degrading enzyme by celiac patients: A pilot-study

(2013) Greetje J Tack   WORLD JOURNAL OF GASTROENTEROLOGY

Screening for Celiac Disease in a North American Population: Sequential Serology and Gastrointestinal Symptoms

(2011) Kent D Katz et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Gluten Causes Gastrointestinal Symptoms in Subjects Without Celiac Disease: A Double-Blind Randomized Placebo-Controlled Trial

(2011) Jessica R Biesiekierski et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Differential Mucosal IL-17 Expression in Two Gliadin-Induced Disorders: Gluten Sensitivity and the Autoimmune Enteropathy Celiac Disease

(2009) Anna Sapone et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

A Food-Grade Enzyme Preparation with Modest Gluten Detoxification Properties

(2009) Jennifer Ehren et al.   PLoS One