The poly-SUMO2/3 protease SENP6 enables assembly of the constitutive centromere-associated network by group deSUMOylation

Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway

(2018) Jianshuang Li et al.   Nature Communications

SUMO targets the APC/C to regulate transition from metaphase to anaphase

(2018) Karolin Eifler et al.   Nature Communications

Converging Small Ubiquitin-like Modifier (SUMO) and Ubiquitin Signaling: Improved Methodology Identifies Co-modified Target Proteins

(2017) Sabine A. G. Cuijpers et al.   MOLECULAR & CELLULAR PROTEOMICS

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor

(2017) Xingyue He et al.   Nature Chemical Biology

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

(2017) Ramesh Kumar et al.   Nature Communications

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Loss of the SUMO protease Ulp2 triggers a specific multichromosome aneuploidy

(2016) Hong-Yeoul Ryu et al.   GENES & DEVELOPMENT

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

A high-yield double-purification proteomics strategy for the identification of SUMO sites

(2016) Ivo A Hendriks et al.   Nature Protocols

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

A comprehensive compilation of SUMO proteomics

(2016) Ivo A. Hendriks et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

(2015) Traver Hart et al.   CELL

Distinct Organization and Regulation of the Outer Kinetochore KMN Network Downstream of CENP-C and CENP-T

(2015) Florencia Rago et al.   CURRENT BIOLOGY

The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface

(2015) Kara L. McKinley et al.   MOLECULAR CELL

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly

(2015) Nathalie Eisenhardt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere

(2015) S. J. Falk et al.   SCIENCE

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly

(2015) Nathalie Eisenhardt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The SENP7 SUMO-Protease Presents a Module of Two HP1 Interaction Motifs that Locks HP1 Protein at Pericentric Heterochromatin

(2015) Kelly Romeo et al.   Cell Reports

Uncovering SUMOylation Dynamics during Cell-Cycle Progression Reveals FoxM1 as a Key Mitotic SUMO Target Protein

(2014) Joost Schimmel et al.   MOLECULAR CELL

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Structural insights into the SENP6 Loop1 structure in complex with SUMO2

(2014) Kamela O. Alegre et al.   PROTEIN SCIENCE

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

SUMO-targeted ubiquitin ligases

(2013) Annie M. Sriramachandran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair

(2013) Alexander J Garvin et al.   EMBO REPORTS

The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly

(2013) Tetsuya Hori et al.   JOURNAL OF CELL BIOLOGY

Ubc9 Sumoylation Controls SUMO Chain Formation and Meiotic Synapsis in Saccharomyces cerevisiae

(2013) Helene Klug et al.   MOLECULAR CELL

Signalling change: signal transduction through the decades

(2013) Nancy E. Hynes et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Linear ubiquitination: a newly discovered regulator of cell signalling

(2013) Eva Rieser et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

CENP-T-W-S-X Forms a Unique Centromeric Chromatin Structure with a Histone-like Fold

(2012) Tatsuya Nishino et al.   CELL

Protein Group Modification and Synergy in the SUMO Pathway as Exemplified in DNA Repair

(2012) Ivan Psakhye et al.   CELL

Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

(2012) Yogesh Kulathu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Function and regulation of SUMO proteases

(2012) Christopher M. Hickey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The SUMO protease SENP7 is a critical component to ensure HP1 enrichment at pericentric heterochromatin

(2012) Christèle Maison et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Dynamics and Mechanism of SUMO Chain Deconjugation by SUMO-specific Proteases

(2011) Miklós Békés et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The fate of metaphase kinetochores is weighed in the balance of SUMOylation during S phase

(2010) Debaditya Mukhopadhyay et al.   CELL CYCLE

The SUMO protease SENP6 is a direct regulator of PML nuclear bodies

(2010) Neil Hattersley et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of DNA Repair through DeSUMOylation and SUMOylation of Replication Protein A Complex

(2010) Hong Dou et al.   MOLECULAR CELL

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

(2010) M. Fenech et al.   MUTAGENESIS

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Post-translational modifications in signal integration

(2010) Yonathan Lissanu Deribe et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quantitative Proteomics Reveals the Function of Unconventional Ubiquitin Chains in Proteasomal Degradation

(2009) Ping Xu et al.   CELL

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

System-Wide Changes to SUMO Modifications in Response to Heat Shock

(2009) F. Golebiowski et al.   Science Signaling

Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML

(2008) Stefan R. Weisshaar et al.   FEBS LETTERS

Structure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7

(2008) Christopher D. Lima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of SUMO-1 Occursin Vivoand Is Conserved through Evolution

(2008) Ivan Matic et al.   JOURNAL OF PROTEOME RESEARCH

The Fast-Growing Business of SUMO Chains

(2008) Helle D. Ulrich   MOLECULAR CELL

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY