Protein Kinase A Is Essential for Invasion of Plasmodium falciparum into Human Erythrocytes

Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion

(2019) Christian Flueck et al.   PLOS BIOLOGY

An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca2+ signalling and motility in Toxoplasma gondii

(2019) Luning Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

(2019) Avnish Patel et al.   PLOS BIOLOGY

Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii

(2018) Alessandro D. Uboldi et al.   PLOS BIOLOGY

A forward genetic screen identifies a negative regulator of rapid Ca2+-dependent cell egress (MS1) in the intracellular parasiteToxoplasma gondii

(2017) James M. McCoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential Role of the PfRh5/PfRipr/CyRPA Complex during Plasmodium falciparum Invasion of Erythrocytes

(2016) Jennifer C. Volz et al.   Cell Host & Microbe

Disrupting the Allosteric Interaction between thePlasmodium falciparumcAMP-dependent Kinase and Its Regulatory Subunit

(2016) Dene R. Littler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium signalling in malaria parasites

(2016) Mathieu Brochet et al.   MOLECULAR MICROBIOLOGY

Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation

(2016) Melissa J. Buskes et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Overlaying Molecular and Temporal Aspects of Malaria Parasite Invasion

(2016) Greta E. Weiss et al.   TRENDS IN PARASITOLOGY

Hierarchical phosphorylation of apical membrane antigen 1 is required for efficient red blood cell invasion by malaria parasites

(2016) Boris Prinz et al.   Scientific Reports

The calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium spp

(2015) Sebastian Lourido et al.   CELL CALCIUM

Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes

(2015) Greta E. Weiss et al.   PLoS Pathogens

Conditional expression of apical membrane antigen 1 inPlasmodium falciparumshows it is required for erythrocyte invasion by merozoites

(2014) Alan Yap et al.   CELLULAR MICROBIOLOGY

Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system

(2014) Mehdi Ghorbal et al.   NATURE BIOTECHNOLOGY

Structural basis of the ultrasensitive calcium indicator GCaMP6

(2014) JingJin Ding et al.   Science China-Life Sciences

The Central Role of cAMP in Regulating Plasmodium falciparum Merozoite Invasion of Human Erythrocytes

(2014) Amrita Dawn et al.   PLoS Pathogens

Inducible Knockdown of Plasmodium Gene Expression Using the glmS Ribozyme

(2013) Parichat Prommana et al.   PLoS One

Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress

(2013) Christine R. Collins et al.   PLoS Pathogens

The Plasmodium falciparum Schizont Phosphoproteome Reveals Extensive Phosphatidylinositol and cAMP-Protein Kinase A Signaling

(2012) Edwin Lasonder et al.   JOURNAL OF PROTEOME RESEARCH

Exploring the Plasmodium falciparum cyclic-adenosine monophosphate (cAMP)-dependent protein kinase (PfPKA) as a therapeutic target

(2012) Nina M. Haste et al.   MICROBES AND INFECTION

A novel mechanism for egress of malarial parasites from red blood cells

(2011) M. Abkarian et al.   BLOOD

Binding ofPlasmodiummerozoite proteins RON2 and AMA1 triggers commitment to invasion

(2011) Prakash Srinivasan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RON2-AMA1 Interaction is a Critical Step in Moving Junction-Dependent Invasion by Apicomplexan Parasites

(2011) Mauld Lamarque et al.   PLoS Pathogens

Cyclic nucleotide signalling in malaria parasites

(2010) David A. Baker   CELLULAR MICROBIOLOGY

Interaction betweenPlasmodium falciparumApical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

(2010) Dave Richard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development

(2010) M. J. Boyle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct External Signals Trigger Sequential Release of Apical Organelles during Erythrocyte Invasion by Malaria Parasites

(2010) Shailja Singh et al.   PLoS Pathogens

Protein Kinase A Dependent Phosphorylation of Apical Membrane Antigen 1 Plays an Important Role in Erythrocyte Invasion by the Malaria Parasite

(2010) Kerstin Leykauf et al.   PLoS Pathogens

Functional Analysis of the Leading Malaria Vaccine Candidate AMA-1 Reveals an Essential Role for the Cytoplasmic Domain in the Invasion Process

(2009) Moritz Treeck et al.   PLoS Pathogens

Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites

(2008) Paul R. Gilson et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Adenylyl Cyclase α and cAMP Signaling Mediate Plasmodium Sporozoite Apical Regulated Exocytosis and Hepatocyte Infection

(2008) Takeshi Ono et al.   PLoS Pathogens