Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans
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Title
Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans
Authors
Keywords
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Journal
TOXICOLOGICAL SCIENCES
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2019-10-03
DOI
10.1093/toxsci/kfz211
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- (2017) Caroline L. Ring et al. ENVIRONMENT INTERNATIONAL
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- (2012) Li Di et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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- Approaches for Assessing Risks to Sensitive Populations: Lessons Learned from Evaluating Risks in the Pediatric Population
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- (2008) Ronald J. Jandacek et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
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- (2008) Dongfang Yang et al. BIOCHEMICAL PHARMACOLOGY
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