Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo Extrapolation

Organic Anion Transporter 2 mediated Hepatic Uptake Contribute to the Clearance of High Permeability - Low Molecular Weight Acid and Zwitterion Drugs: Evaluation using 25 drugs.

(2018) Emi Kimoto et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Influence of Maturation on In Vivo Tissue to Plasma Partition Coefficients for Cis - and Trans -Permethrin

(2017) Manoj Amaraneni et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Brain uptake of deltamethrin in rats as a function of plasma protein binding and blood–brain barrier maturation

(2017) Manoj Amaraneni et al.   NEUROTOXICOLOGY

Toxicokinetics of Deltamethrin: Dosage Dependency, Vehicle Effects, and Low-Dose Age-Equivalent Dosimetry in Rats

(2017) Tanzir Mortuza et al.   TOXICOLOGICAL SCIENCES

Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

(2016) Mikael Boberg et al.   DRUG METABOLISM AND DISPOSITION

Locomotor activity and tissue levels following acute administration of lambda- and gamma-cyhalothrin in rats

(2016) Virginia C. Moser et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Plasma protein binding limits the blood brain barrier permeation of the pyrethroid insecticide, deltamethrin

(2016) Manoj Amaraneni et al.   TOXICOLOGY LETTERS

Time profiles and toxicokinetic parameters of key biomarkers of exposure to cypermethrin in orally exposed volunteers compared with previously available kinetic data following permethrin exposure

(2015) Mylène Ratelle et al.   JOURNAL OF APPLIED TOXICOLOGY

Environmentally relevant mixing ratios in cumulative assessments: A study of the kinetics of pyrethroids and their ester cleavage metabolites in blood and brain; and the effect of a pyrethroid mixture on the motor activity of rats

(2014) James M. Starr et al.   TOXICOLOGY

Measurement of plasma protein and lipoprotein binding of pyrethroids

(2014) Pankaj K. Sethi et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Quantitativein vitrotoin vivoextrapolation of cell-based toxicity assay results

(2012) Miyoung Yoon et al.   CRITICAL REVIEWS IN TOXICOLOGY

Molecular mechanisms of pyrethroid insecticide neurotoxicity: recent advances

(2011) David M. Soderlund   ARCHIVES OF TOXICOLOGY

Correlation of tissue concentrations of the pyrethroid bifenthrin with neurotoxicity in the rat

(2011) Edward J. Scollon et al.   TOXICOLOGY

Age, Dose, and Time-Dependency of Plasma and Tissue Distribution of Deltamethrin in Immature Rats

(2010) Kyu-Bong Kim et al.   TOXICOLOGICAL SCIENCES

Evaluation of deltamethrin kinetics and dosimetry in the maturing rat using a PBPK model

(2010) Rogelio Tornero-Velez et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Age- and Sex-Related Expression and Activity of Carboxylesterase 1 and 2 in Mouse and Human Liver

(2009) H.-J. Zhu et al.   DRUG METABOLISM AND DISPOSITION

Lactational Transfer of Manganese in Rats: Predicting Manganese Tissue Concentration in the Dam and Pups from Inhalation Exposure with a Pharmacokinetic Model

(2009) Miyoung Yoon et al.   TOXICOLOGICAL SCIENCES

Evaluating Placental Transfer and Tissue Concentrations of Manganese in the Pregnant Rat and Fetuses after Inhalation Exposures with a PBPK Model

(2009) Miyoung Yoon et al.   TOXICOLOGICAL SCIENCES

Lymphatic and portal vein absorption of organochlorine compounds in rats

(2008) Ronald J. Jandacek et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Methods for Predicting In Vivo Pharmacokinetics Using Data from In Vitro Assays

(2008) J. Houston et al.   CURRENT DRUG METABOLISM

Rate-Limiting Steps in Hepatic Drug Clearance: Comparison of Hepatocellular Uptake and Metabolism with Microsomal Metabolism of Saquinavir, Nelfinavir, and Ritonavir

(2008) A. J. Parker et al.   DRUG METABOLISM AND DISPOSITION

In Vitro Metabolism of Pyrethroid Pesticides by Rat and Human Hepatic Microsomes and Cytochrome P450 Isoforms

(2008) E. J. Scollon et al.   DRUG METABOLISM AND DISPOSITION

The ontogeny of drug metabolism enzymes and implications for adverse drug events

(2008) Ronald N. Hines   PHARMACOLOGY & THERAPEUTICS

Manganese Tissue Dosimetry in Rats and Monkeys: Accounting for Dietary and Inhaled Mn with Physiologically based Pharmacokinetic Modeling

(2008) Andy Nong et al.   TOXICOLOGICAL SCIENCES