Hybrid Electron Microscopy Normal Mode Analysis with Scipion

Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution

(2019) Xiao Fan et al.   Nature Communications

Likelihood-based structural analysis of electron microscopy images

(2018) Pilar Cossio et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system

(2018) Yuxi Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Variability from Noisy Tomographic Projections

(2018) Joakim Andén et al.   SIAM Journal on Imaging Sciences

cisTEM, user-friendly software for single-particle image processing

(2018) Timothy Grant et al.   eLife

Visualization of chemical modifications in the human 80S ribosome structure

(2017) S. Kundhavai Natchiar et al.   NATURE

Structure of phycobilisome from the red alga Griffithsia pacifica

(2017) Jun Zhang et al.   NATURE

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Single-particle cryo-EM-Improved ab initio 3D reconstruction with SIMPLE/PRIME

(2017) Cyril F. Reboul et al.   PROTEIN SCIENCE

StructMap: Elastic Distance Analysis of Electron Microscopy Maps for Studying Conformational Changes

(2016) Carlos Oscar Sanchez Sorzano et al.   BIOPHYSICAL JOURNAL

Coarse-Graining of Volumes for Modeling of Structure and Dynamics in Electron Microscopy: Algorithm to Automatically Control Accuracy of Approximation

(2016) Slavica Jonic et al.   IEEE Journal of Selected Topics in Signal Processing

Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy

(2016) J.M. de la Rosa-Trevín et al.   JOURNAL OF STRUCTURAL BIOLOGY

Denoising of high-resolution single-particle electron-microscopy density maps by their approximation using three-dimensional Gaussian functions

(2016) S. Jonić et al.   JOURNAL OF STRUCTURAL BIOLOGY

Continuous changes in structure mapped by manifold embedding of single-particle data in cryo-EM

(2016) Joachim Frank et al.   METHODS

Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution

(2016) Thi Hoang Duong Nguyen et al.   NATURE

Near-atomic resolution visualization of human transcription promoter opening

(2016) Yuan He et al.   NATURE

2.3 A resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

(2016) S. Banerjee et al.   SCIENCE

Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome

(2016) Priyanka D Abeyrathne et al.   eLife

Directly reconstructing principal components of heterogeneous particles from cryo-EM images

(2015) Hemant D. Tagare et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the human 80S ribosome

(2015) Heena Khatter et al.   NATURE

Structure of the E. coli ribosome–EF-Tu complex at

(2015) Niels Fischer et al.   NATURE

An atomic structure of human γ-secretase

(2015) Xiao-chen Bai et al.   NATURE

2.2 A resolution cryo-EM structure of  -galactosidase in complex with a cell-permeant inhibitor

(2015) A. Bartesaghi et al.   SCIENCE

Covariance Matrix Estimation for the Cryo-EM Heterogeneity Problem

(2015) E. Katsevich et al.   SIAM Journal on Imaging Sciences

Efficient initial volume determination from electron microscopy images of single particles

(2014) Javier Vargas et al.   BIOINFORMATICS

Hybrid Electron Microscopy Normal Mode Analysis graphical interface and protocol

(2014) Carlos Oscar S. Sorzano et al.   JOURNAL OF STRUCTURAL BIOLOGY

Trajectories of the ribosome as a Brownian nanomachine

(2014) Ali Dashti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Iterative Elastic 3D-to-2D Alignment Method Using Normal Modes for Studying Structural Dynamics of Large Macromolecular Complexes

(2014) Qiyu Jin et al.   STRUCTURE

Likelihood-based classification of cryo-EM images using FREALIGN

(2013) Dmitry Lyumkis et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

A Bayesian View on Cryo-EM Structure Determination

(2011) Sjors H.W. Scheres   JOURNAL OF MOLECULAR BIOLOGY

Identifying Conformational States of Macromolecules by Eigen-Analysis of Resampled Cryo-EM Images

(2011) Pawel A. Penczek et al.   STRUCTURE

A clustering approach to multireference alignment of single-particle projections in electron microscopy

(2010) C.O.S. Sorzano et al.   JOURNAL OF STRUCTURAL BIOLOGY

3.88 Å structure of cytoplasmic polyhedrosis virus by cryo-electron microscopy

(2008) Xuekui Yu et al.   NATURE

Structure of the 30S translation initiation complex

(2008) Angelita Simonetti et al.   NATURE

Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction

(2008) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection and separation of heterogeneity in molecular complexes by statistical analysis of their two-dimensional projections

(2007) Nadav Elad et al.   JOURNAL OF STRUCTURAL BIOLOGY