Structure of the E. coli ribosome–EF-Tu complex at

Synergy of Streptogramin Antibiotics Occurs Independently of Their Effects on Translation

(2014) Jonas Noeske et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Amicoumacin A Inhibits Translation by Stabilizing mRNA Interaction with the Ribosome

(2014) Yury S. Polikanov et al.   MOLECULAR CELL

Structure of  -galactosidase at 3.2-A resolution obtained by cryo-electron microscopy

(2014) A. Bartesaghi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic model of the F420-reducing [NiFe] hydrogenase by electron cryo-microscopy using a direct electron detector

(2014) Matteo Allegretti et al.   eLife

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine

(2014) Wilson Wong et al.   eLife

Deformable elastic network refinement for low-resolution macromolecular crystallography

(2014) Gunnar F. Schröder et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Energy barriers and driving forces in tRNA translocation through the ribosome

(2013) Lars V Bock et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations

(2013) Jun Jiang et al.   NUCLEIC ACIDS RESEARCH

Control of Ribosomal Subunit Rotation by Elongation Factor G

(2013) A. Pulk et al.   SCIENCE

Ribosome engineering to promote new crystal forms

(2012) Maria Selmer et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Fitness Cost and Interference of Arm/Rmt Aminoglycoside Resistance with the RsmF Housekeeping Methyltransferases

(2012) Belen Gutierrez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Correcting pervasive errors in RNA crystallography through enumerative structure prediction

(2012) Fang-Chieh Chou et al.   NATURE METHODS

Impact of methylations of m2G966/m5C967 in 16S rRNA on bacterial fitness and translation initiation

(2012) Dmitry E. Burakovsky et al.   NUCLEIC ACIDS RESEARCH

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

Modelling dynamics in protein crystal structures by ensemble refinement

(2012) B Tom Burnley et al.   eLife

Inactivation of the Indigenous Methyltransferase RlmN in Staphylococcus aureus Increases Linezolid Resistance

(2011) Jacqueline M. LaMarre et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Methylated 23S rRNA nucleotide m2G1835 of Escherichia coli ribosome facilitates subunit association

(2011) Ilya A. Osterman et al.   BIOCHIMIE

Helix 69 Is Key for Uniformity during Substrate Selection on the Ribosome

(2011) Rodrigo F. Ortiz-Meoz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improved molecular replacement by density- and energy-guided protein structure optimization

(2011) Frank DiMaio et al.   NATURE

How mutations in tRNA distant from the anticodon affect the fidelity of decoding

(2011) T Martin Schmeing et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structures of the Bacterial Ribosome in Classical and Hybrid States of tRNA Binding

(2011) J. A. Dunkle et al.   SCIENCE

Atomic Model of CPV Reveals the Mechanism Used by This Single-Shelled Virus to Economically Carry Out Functions Conserved in Multishelled Reoviruses

(2011) Xuekui Yu et al.   STRUCTURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions

(2010) Grigore D. Pintilie et al.   JOURNAL OF STRUCTURAL BIOLOGY

Super-resolution biomolecular crystallography with low-resolution data

(2010) Gunnar F. Schröder et al.   NATURE

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

(2010) Niels Fischer et al.   NATURE

Structural rearrangements of the ribosome at the tRNA proofreading step

(2010) Lasse Jenner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The crystal structure of unmodified tRNA Phe from Escherichia coli

(2010) Robert T. Byrne et al.   NUCLEIC ACIDS RESEARCH

Structural signatures of antibiotic binding sites on the ribosome

(2010) Hilda David-Eden et al.   NUCLEIC ACIDS RESEARCH

Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function

(2010) H. Demirci et al.   RNA

The Mechanism for Activation of GTP Hydrolysis on the Ribosome

(2010) R. M. Voorhees et al.   SCIENCE

The Native 3D Organization of Bacterial Polysomes

(2009) Florian Brandt et al.   CELL

Refinement of Protein Structures into Low-Resolution Density Maps Using Rosetta

(2009) Frank DiMaio et al.   JOURNAL OF MOLECULAR BIOLOGY

Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA

(2009) Satoshi Kimura et al.   NUCLEIC ACIDS RESEARCH

Structural Insight into Nascent Polypeptide Chain-Mediated Translational Stalling

(2009) B. Seidelt et al.   SCIENCE

The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA

(2009) T. M. Schmeing et al.   SCIENCE

Role of 16S ribosomal RNA methylations in translation initiation in Escherichia coli

(2008) Gautam Das et al.   EMBO JOURNAL

Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit∥

(2008) Joseph A. Ippolito et al.   JOURNAL OF MEDICINAL CHEMISTRY

An Indigenous Posttranscriptional Modification in the Ribosomal Peptidyl Transferase Center Confers Resistance to an Array of Protein Synthesis Inhibitors

(2008) Seok-Ming Toh et al.   JOURNAL OF MOLECULAR BIOLOGY

The ybiN Gene of Escherichia coli Encodes Adenine-N6 Methyltransferase Specific for Modification of A1618 of 23 S Ribosomal RNA, a Methylated Residue Located Close to the Ribosomal Exit Tunnel

(2007) Petr V. Sergiev et al.   JOURNAL OF MOLECULAR BIOLOGY