Near-atomic resolution visualization of human transcription promoter opening

Structure of transcribing mammalian RNA polymerase II

(2016) Carrie Bernecky et al.   NATURE

Structure of promoter-bound TFIID and model of human pre-initiation complex assembly

(2016) Robert K. Louder et al.   NATURE

Crystal Structure of the Rad3/XPD Regulatory Domain of Ssl1/p44

(2015) Jin Seok Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH

(2015) Jie Luo et al.   MOLECULAR CELL

Architecture of the RNA polymerase II–Mediator core initiation complex

(2015) C. Plaschka et al.   NATURE

Structure of an RNA polymerase II preinitiation complex

(2015) Kenji Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure of the TFIIH p34 Subunit Reveals a Von Willebrand Factor A Like Fold

(2014) Dominik R. Schmitt et al.   PLoS One

Structural basis for nuclear import of splicing factors by human Transportin 3

(2014) G. N. Maertens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beam-induced motion correction for sub-megadalton cryo-EM particles

(2014) Sjors HW Scheres   eLife

Structure of the C-terminal half of human XPB helicase and the impact of the disease-causing mutation XP11BE

(2013) Eduardo Hilario et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

One number does not fit all: Mapping local variations in resolution in cryo-EM reconstructions

(2013) Giovanni Cardone et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structural visualization of key steps in human transcription initiation

(2013) Yuan He et al.   NATURE

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Structural mimicry in transcription regulation of human RNA polymerase II by the DNA helicase RECQL5

(2013) Susanne A Kassube et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-resolution structure of TBP with TAF1 reveals anchoring patterns in transcriptional regulation

(2013) Madhanagopal Anandapadamanaban et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Scalable web services for the PSIPRED Protein Analysis Workbench

(2013) Daniel W. A. Buchan et al.   NUCLEIC ACIDS RESEARCH

Transcription initiation by human RNA polymerase II visualized at single-molecule resolution

(2012) A. Revyakin et al.   GENES & DEVELOPMENT

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Structure and function of the initially transcribing RNA polymerase II–TFIIB complex

(2012) Sarah Sainsbury et al.   NATURE

Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening

(2012) Sebastian Grünberg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Subunit architecture of general transcription factor TFIIH

(2012) B. J. Gibbons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Transcription Initiation

(2012) Y. Zhang et al.   SCIENCE

Outcome of the First Electron Microscopy Validation Task Force Meeting

(2012) Richard Henderson et al.   STRUCTURE

Structural basis of initial RNA polymerase II transcription

(2011) Alan C M Cheung et al.   EMBO JOURNAL

The Phenix software for automated determination of macromolecular structures

(2011) Paul D. Adams et al.   METHODS

Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP

(2011) Petra Wollmann et al.   NATURE

Transcription factor TFIIF is not required for initiation by RNA polymerase II, but it is essential to stabilize transcription factor TFIIB in early elongation complexes

(2011) P. Cabart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Initiation Complex Structure and Promoter Proofreading

(2011) X. Liu et al.   SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Architecture of the RNA polymerase II–TFIIF complex revealed by cross-linking and mass spectrometry

(2010) Zhuo Angel Chen et al.   EMBO JOURNAL

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Position of the general transcription factor TFIIF within the RNA polymerase II transcription preinitiation complex

(2009) Jesse Eichner et al.   EMBO JOURNAL

Appion: An integrated, database-driven pipeline to facilitate EM image processing

(2009) Gabriel C. Lander et al.   JOURNAL OF STRUCTURAL BIOLOGY

DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy

(2009) N.R. Voss et al.   JOURNAL OF STRUCTURAL BIOLOGY

RNA polymerase II–TFIIB structure and mechanism of transcription initiation

(2009) Dirk Kostrewa et al.   NATURE

Structure of an RNA Polymerase II-TFIIB Complex and the Transcription Initiation Mechanism

(2009) X. Liu et al.   SCIENCE

XPD Helicase Structures and Activities: Insights into the Cancer and Aging Phenotypes from XPD Mutations

(2008) Li Fan et al.   CELL

Structural insight into the TFIIE–TFIIH interaction: TFIIE and p53 share the binding region on TFIIH

(2008) Masahiko Okuda et al.   EMBO JOURNAL

Structural basis for group A trichothiodystrophy

(2008) Denis E Kainov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformational changes of a Swi2/Snf2 ATPase during its mechano-chemical cycle

(2008) Robert Lewis et al.   NUCLEIC ACIDS RESEARCH

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

(2008) Leonardo G. Trabuco et al.   STRUCTURE

Crystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPD

(2008) Stefanie C Wolski et al.   PLOS BIOLOGY