Dietary Supplementation of the Antioxidant Curcumin Halts Systemic LPS-Induced Neuroinflammation-Associated Neurodegeneration and Memory/Synaptic Impairment via the JNK/NF-κB/Akt Signaling Pathway in Adult Rats

Neuroprotective Effects of Curcumin on IL-1β-Induced Neuronal Apoptosis and Depression-Like Behaviors Caused by Chronic Stress in Rats

(2019) Cuiqin Fan et al.   Frontiers in Cellular Neuroscience

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

(2019) Tahir Muhammad et al.   Nutrients

Astaxanthin Ameliorates Lipopolysaccharide-Induced Neuroinflammation, Oxidative Stress and Memory Dysfunction through Inactivation of the Signal Transducer and Activator of Transcription 3 Pathway

(2019) Ji Han et al.   Marine Drugs

Lipopolysaccharide-Induced Neuroinflammation as a Bridge to Understand Neurodegeneration

(2019) Carla Ribeiro Alvares Batista et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Beneficial Role of Phytochemicals on Oxidative Stress and Age-Related Diseases

(2019) Cinzia Forni et al.   Biomed Research International

Caffeine Modulates Cadmium-Induced Oxidative Stress, Neuroinflammation, and Cognitive Impairments by Regulating Nrf-2/HO-1 In Vivo and In Vitro

(2019) Amjad Khan et al.   Journal of Clinical Medicine

Flavonoid-rich ethanol extract from the leaves of Diospyros kaki attenuates cognitive deficits, amyloid-beta production, oxidative stress, and neuroinflammation in APP/PS1 transgenic mice

(2018) Yingjuan Ma et al.   BRAIN RESEARCH

The effects of melatonin and curcumin on the expression of SIRT2, Bcl-2 and Bax in the hippocampus of adult rats

(2018) Arzu Keskin-Aktan et al.   BRAIN RESEARCH BULLETIN

Gypenosides Attenuate Lipopolysaccharide-Induced Neuroinflammation and Memory Impairment in Rats

(2018) Bombi Lee et al.   Evidence-based Complementary and Alternative Medicine

MicroRNA-132 attenuates LPS-induced inflammatory injury by targeting TRAF6 in neuronal cell line HT-22

(2018) Yang-Fei Ji et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Protective effects of Curcumin on acrolein-induced neurotoxicity in HT22 mouse hippocampal cells

(2018) Lan-Ying Shi et al.   Pharmacological Reports

Lipopolysaccharide Associates with Amyloid Plaques, Neurons and Oligodendrocytes in Alzheimer’s Disease Brain: A Review

(2018) Xinhua Zhan et al.   Frontiers in Aging Neuroscience

Curcumin alleviates pain and improves cognitive impairment in a rat model of cobra venom-induced trigeminal neuralgia

(2018) Li Zhang et al.   Journal of Pain Research

Neuroprotective and Neurological/Cognitive Enhancement Effects of Curcumin after Brain Ischemia Injury with Alzheimer’s Disease Phenotype

(2018) Ryszard Pluta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model

(2018) Tahir Muhammad et al.   Journal of Neuroimmune Pharmacology

Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis

(2018) Bingxu Huang et al.   Frontiers in Immunology

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

Inflammatory responses and inflammation-associated diseases in organs

(2017) Linlin Chen et al.   Oncotarget

Curcumin inhibits apoptosis by modulating Bax/Bcl-2 expression and alleviates oxidative stress in testes of streptozotocin-induced diabetic rats

(2017) Lingling Zhao et al.   Therapeutics and Clinical Risk Management

Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK

(2016) Duy-Khanh Dang et al.   Journal of Neuroinflammation

Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway

(2016) Haroon Badshah et al.   Scientific Reports

Lipopolysaccharide-induced memory impairment in rats is preventable using 7-nitroindazole

(2015) Akbar Anaeigoudari et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Curcumin, Inflammation, and Chronic Diseases: How Are They Linked?

(2015) Yan He et al.   MOLECULES

Curcumin and Apigenin - novel and promising therapeutics against chronic neuroinflammation in Alzheimer′s disease

(2015) Gerald Münch et al.   Neural Regeneration Research

Mitochondrial ROS govern the LPS-induced pro-inflammatory response in microglia cells by regulating MAPK and NF-κB pathways

(2015) Junghyung Park et al.   NEUROSCIENCE LETTERS

Activated microglia contribute to neuronal apoptosis in Toxoplasmic encephalitis

(2014) Yi-hua Zhang et al.   Parasites & Vectors

Neuroinflammation and Neurodegeneration in Adult Rat Brain from Binge Ethanol Exposure: Abrogation by Docosahexaenoic Acid

(2014) Nuzhath Tajuddin et al.   PLoS One

Valproic acid potentiates curcumin-mediated neuroprotection in lipopolysaccharide induced rats

(2014) Amira Zaky et al.   Frontiers in Cellular Neuroscience

Calcium dysregulation and neuroinflammation: Discrete and integrated mechanisms for age-related synaptic dysfunction

(2013) Diana M. Sama et al.   AGEING RESEARCH REVIEWS

Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor

(2013) Hideaki Ogiwara et al.   CARCINOGENESIS

Role of Redox Signaling in Neuroinflammation and Neurodegenerative Diseases

(2013) Hsi-Lung Hsieh et al.   Biomed Research International

Inhibitors of Microglial Neurotoxicity: Focus on Natural Products

(2011) Dong Kug Choi et al.   MOLECULES

Fluoxetine prevents LPS-induced degeneration of nigral dopaminergic neurons by inhibiting microglia-mediated oxidative stress

(2010) Eun S. Chung et al.   BRAIN RESEARCH

Inflammation and apoptosis in aortic tissues of aged type II diabetes: Amelioration with α-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism

(2010) Milad S. Bitar et al.   LIFE SCIENCES

Neuroprotective effects of the polyphenolic antioxidant agent, Curcumin, against homocysteine-induced cognitive impairment and oxidative stress in the rat

(2010) Amin Ataie et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Neuroprotective effect of curcumin on transient focal cerebral ischemia in rats

(2008) Jing Zhao et al.   BRAIN RESEARCH

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

(2008) Jae Lee et al.   Journal of Neuroinflammation

Stress as a neuroinflammatory condition in brain: Damaging and protective mechanisms

(2008) Borja García-Bueno et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS