The Role of Oxidative Stress in Common Risk Factors and Mechanisms of Cardio-Cerebrovascular Ischemia and Depression

The neuroactive potential of the human gut microbiota in quality of life and depression

(2019) Mireia Valles-Colomer et al.   Nature Microbiology

Neuro-Protective Role of Metformin in Patients with Acute Stroke and Type 2 Diabetes Mellitus via AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Pathway and Oxidative Stress

(2019) Min Zhao et al.   MEDICAL SCIENCE MONITOR

Antioxidant Properties of Fucoidan Alleviate Acceleration and Exacerbation of Hippocampal Neuronal Death Following Transient Global Cerebral Ischemia in High-Fat Diet-Induced Obese Gerbils

(2019) Ji Ahn et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dual inhibition of NADPH oxidases and xanthine oxidase potently prevents salt-induced stroke in stroke-prone spontaneously hypertensive rats

(2019) Davis Ngarashi et al.   HYPERTENSION RESEARCH

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

MALAT1/miR-15b-5p/MAPK1 mediates endothelial progenitor cells autophagy and affects coronary atherosclerotic heart disease via mTOR signaling pathway

(2019) Ying Zhu et al.   Aging-US

Neuroprotection of Resveratrol Against Focal Cerebral Ischemia/Reperfusion Injury in Mice Through a Mechanism Targeting Gut-Brain Axis

(2019) Zhongci Dou et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Gut Microbiota in Alzheimer’s Disease, Depression, and Type 2 Diabetes Mellitus: The Role of Oxidative Stress

(2019) Maria Luca et al.   Oxidative Medicine and Cellular Longevity

Long-term and recent trends in hypertension awareness, treatment, and control in 12 high-income countries: an analysis of 123 nationally representative surveys

(2019) Bin Zhou et al.   LANCET

Mortality, morbidity, and risk factors in China and its provinces, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2019) Maigeng Zhou et al.   LANCET

Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice

(2019) Wenqi Gao et al.   METABOLIC BRAIN DISEASE

Emerging therapeutic targets associated with the immune system in patients with intracerebral haemorrhage (ICH): From mechanisms to translation

(2019) Anwen Shao et al.   EBioMedicine

The relationship between oxidized low-density lipoprotein and the NIHSS score among patients with acute ischemic stroke: The SOS-Stroke Study

(2018) Anxin Wang et al.   ATHEROSCLEROSIS

Replicable and Coupled Changes in Innate and Adaptive Immune Gene Expression in Two Case-Control Studies of Blood Microarrays in Major Depressive Disorder

(2018) Gwenaël G.R. Leday et al.   BIOLOGICAL PSYCHIATRY

The water extract of tutsan ( Hypericum androsaemum L.) red berries exerts antidepressive-like effects and in vivo antioxidant activity in a mouse model of post-stroke depression

(2018) Seyed Mohammad Nabavi et al.   BIOMEDICINE & PHARMACOTHERAPY

Curcumin prevents strokes in stroke-prone spontaneously hypertensive rats by improving vascular endothelial function

(2018) Cong Lan et al.   BMC Cardiovascular Disorders

Variation of genes involved in oxidative and nitrosative stresses in depression

(2018) Paulina Wigner et al.   EUROPEAN PSYCHIATRY

Dioscin protects against coronary heart disease by reducing oxidative stress and inflammation via Sirt1/Nrf2 and p38 MAPK pathways

(2018) Bo Yang et al.   Molecular Medicine Reports

Nicotine alleviates chronic stress-induced anxiety and depressive-like behavior and hippocampal neuropathology via regulating autophagy signaling

(2018) Xi Xiao et al.   NEUROCHEMISTRY INTERNATIONAL

Targeting glycogen synthase kinase-3 for oxidative stress and neuroinflammation: Opportunities, challenges and future directions for cerebral stroke management

(2018) Anil Kumar Rana et al.   NEUROPHARMACOLOGY

RIP1K Contributes to Neuronal and Astrocytic Cell Death in Ischemic Stroke via Activating Autophagic-lysosomal Pathway

(2018) Yong Ni et al.   NEUROSCIENCE

Risk of ischemic stroke in metabolically healthy obesity: A nationwide population-based study

(2018) Hyun-Jung Lee et al.   PLoS One

Interactions between pro-inflammatory cytokines and statins on depression in patients with acute coronary syndrome

(2018) Sung-Wan Kim et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A neuro-immune, neuro-oxidative and neuro-nitrosative model of prenatal and postpartum depression

(2018) Chutima Roomruangwong et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Blood-brain barrier dysfunction and recovery after ischemic stroke

(2018) Xiaoyan Jiang et al.   PROGRESS IN NEUROBIOLOGY

Autophagy in ischemic stroke

(2018) Pei Wang et al.   PROGRESS IN NEUROBIOLOGY

Relationship Between Plasma 8‐OH‐Deoxyguanosine and Cardiovascular Disease and Survival in Type 2 Diabetes Mellitus: Results From the ADVANCE Trial

(2018) Merlin C. Thomas et al.   Journal of the American Heart Association

13 reasons why the brain is susceptible to oxidative stress

(2018) James Nathan Cobley et al.   Redox Biology

The Burden of Cardiovascular Diseases Among US States, 1990-2016

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PHACTR1 regulates oxidative stress and inflammation to coronary artery endothelial cells via interaction with NF-κB/p65

(2018) Zhihui Zhang et al.   ATHEROSCLEROSIS

2,3,5,4′-Tetrahydroxystilbene-2-O-beta-D-glucoside Reverses Stress-Induced Depression via Inflammatory and Oxidative Stress Pathways

(2018) Cheng-Yong Jiang et al.   Oxidative Medicine and Cellular Longevity

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Spencer L James et al.   LANCET

Depression

(2018) Gin S Malhi et al.   LANCET

Oxidative Stress in Cardiac Tissue of Patients Undergoing Coronary Artery Bypass Graft Surgery: The Effects of Overweight and Obesity

(2018) Yves Gramlich et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress and the Microbiota-Gut-Brain Axis

(2018) Laura Dumitrescu et al.   Oxidative Medicine and Cellular Longevity

Inflammation in older subjects with early- and late-onset depression in the NESDO study: a cross-sectional and longitudinal case-only design

(2018) M.P. Rozing et al.   PSYCHONEUROENDOCRINOLOGY

Mechanisms and Therapeutic Targets of Depression After Intracerebral Hemorrhage

(2018) Yinan Wu et al.   Frontiers in Psychiatry

A longitudinal study of neurotrophic, oxidative, and inflammatory markers in first-onset depression in midlife women

(2017) Matheus A. Pasquali et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Association between oxidized low-density lipoprotein and cognitive impairment in patients with ischemic stroke

(2017) A. Wang et al.   EUROPEAN JOURNAL OF NEUROLOGY

Memantine attenuates cell apoptosis by suppressing the calpain-caspase-3 pathway in an experimental model of ischemic stroke

(2017) Bin Chen et al.   EXPERIMENTAL CELL RESEARCH

Malondialdehyde: A novel predictive biomarker for post-stroke depression

(2017) Zhihua Liu et al.   JOURNAL OF AFFECTIVE DISORDERS

Interplay between Notch and p53 promotes neuronal cell death in ischemic stroke

(2017) Priyanka Balaganapathy et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A differential expression of uncoupling protein-2 associates with renal damage in stroke-resistant spontaneously hypertensive rat/stroke-prone spontaneously hypertensive rat-derived stroke congenic lines

(2017) Speranza Rubattu et al.   JOURNAL OF HYPERTENSION

Depressive-Like Behaviors Are Regulated by NOX1/NADPH Oxidase by Redox Modification of NMDA Receptor 1

(2017) Masakazu Ibi et al.   JOURNAL OF NEUROSCIENCE

Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2017) Mohsen Naghavi et al.   LANCET

Increased Root Canal Endotoxin Levels are Associated with Chronic Apical Periodontitis, Increased Oxidative and Nitrosative Stress, Major Depression, Severity of Depression, and a Lowered Quality of Life

(2017) Cinthya Gomes et al.   MOLECULAR NEUROBIOLOGY

Exploring the association between childhood and adolescent obesity and depression: a meta-analysis

(2017) Ying-Hui Quek et al.   Obesity Reviews

Depressive disorder and gastrointestinal dysfunction after myocardial infarct are associated with abnormal tryptophan-5-hydroxytryptamine metabolism in rats

(2017) Xiaofang Lu et al.   PLoS One

Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child

(2017) Patrick M Catalano et al.   BMJ-British Medical Journal

Diabetes and lifetime risk of coronary heart disease

(2017) Tanvir Chowdhury Turin et al.   Primary Care Diabetes

Cerebral Hypoperfusion and Other Shared Brain Pathologies in Ischemic Stroke and Alzheimer’s Disease

(2017) Shuying Dong et al.   Translational Stroke Research

A Combination of Three Repurposed Drugs Administered at Reperfusion as a Promising Therapy for Postischemic Brain Injury

(2017) I-Chen Yu et al.   Translational Stroke Research

Vinpocetine Inhibits NF-κB-Dependent Inflammation in Acute Ischemic Stroke Patients

(2017) Fang Zhang et al.   Translational Stroke Research

Ischemic Preconditioning Protects Astrocytes against Oxygen Glucose Deprivation Via the Nuclear Erythroid 2-Related Factor 2 Pathway

(2017) Srinivasan V. Narayanan et al.   Translational Stroke Research

Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child

(2017) Patrick M Catalano et al.   BMJ-British Medical Journal

Significant Association Between Low Mitochondrial DNA Content in Peripheral Blood Leukocytes and Ischemic Stroke

(2017) Li‐Ming Lien et al.   Journal of the American Heart Association

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

(2017) Yuri Milaneschi et al.   JAMA Psychiatry

Psychological Stress, Inflammation, and Coronary Heart Disease

(2017) Petra H. Wirtz et al.   Current Cardiology Reports

Phellinus linteus Mycelium Alleviates Myocardial Ischemia-Reperfusion Injury through Autophagic Regulation

(2017) Hsing-Hui Su et al.   Frontiers in Pharmacology

BICAO-induced ischaemia caused depressive-like behaviours and caspase-8/-9-dependent brain regional neural cell apoptosis in mice

(2017) Shuiqiao Liu et al.   JOURNAL OF INVESTIGATIVE MEDICINE

The GLP-1 receptor agonists exendin-4 and liraglutide alleviate oxidative stress and cognitive and micturition deficits induced by middle cerebral artery occlusion in diabetic mice

(2016) Ping-Chia Li et al.   BMC NEUROSCIENCE

Intracerebroventricular administration of TNF-like weak inducer of apoptosis induces depression-like behavior and cognitive dysfunction in non-autoimmune mice

(2016) Jing Wen et al.   BRAIN BEHAVIOR AND IMMUNITY

The Link Between Inflammatory Disorders and Coronary Heart Disease: a Look at Recent Studies and Novel Drugs in Development

(2016) H. Teague et al.   Current Atherosclerosis Reports

Depression predictors within six months of ischemic stroke: The DEPRESS Study

(2016) Vincent Guiraud et al.   International Journal of Stroke

Pomegranate peel extract attenuates oxidative stress by decreasing coronary angiotensin-converting enzyme (ACE) activity in hypertensive female rats

(2016) Roger L. dos Santos et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

(2016) Corinne Benakis et al.   NATURE MEDICINE

Depression and coronary heart disease

(2016) Robert M. Carney et al.   Nature Reviews Cardiology

The bowel and beyond: the enteric nervous system in neurological disorders

(2016) Meenakshi Rao et al.   Nature Reviews Gastroenterology & Hepatology

Assessment of Mitochondrial Dysfunction and Monoamine Oxidase Contribution to Oxidative Stress in Human Diabetic Hearts

(2016) O. M. Duicu et al.   Oxidative Medicine and Cellular Longevity

Gut Microbiota, Bacterial Translocation, and Interactions with Diet: Pathophysiological Links between Major Depressive Disorder and Non-Communicable Medical Comorbidities

(2016) Anastasiya Slyepchenko et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Decreased expression of heme oxygenase is associated with depressive symptoms and may contribute to depressive and hypertensive comorbidity

(2016) Joanna Robaczewska et al.   REDOX REPORT

Ischemic Heart Disease in Women

(2016) Jennifer H. Mieres et al.   JACC-Cardiovascular Imaging

Association between inflammatory cytokines and the risk of post-stroke depression, and the effect of depression on outcomes of patients with ischemic stroke in a 2-year prospective study

(2016) Jian-Tong Jiao et al.   Experimental and Therapeutic Medicine

Post-Stroke Depression Modulation and in Vivo Antioxidant Activity of Gallic Acid and Its Synthetic Derivatives in a Murine Model System

(2016) Seyed Nabavi et al.   Nutrients

Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice

(2016) Yang Yao et al.   Translational Stroke Research

Mechanisms, Imaging, and Therapy in Stroke Recovery

(2016) Changhong Xing et al.   Translational Stroke Research

Increased 12/15-Lipoxygenase Leads to Widespread Brain Injury Following Global Cerebral Ischemia

(2016) Kazim Yigitkanli et al.   Translational Stroke Research

Evidence of perceived psychosocial stress as a risk factor for stroke in adults: a meta-analysis

(2015) Joanne Booth et al.   BMC Neurology

Insufficient glucocorticoid signaling and elevated inflammation in coronary heart disease patients with comorbid depression

(2015) Naghmeh Nikkheslat et al.   BRAIN BEHAVIOR AND IMMUNITY

Oxidative Stress Drivers and Modulators in Obesity and Cardiovascular Disease: From Biomarkers to Therapeutic Approach

(2015) F. Santilli et al.   CURRENT MEDICINAL CHEMISTRY

Antioxidant treatment ameliorates experimental diabetes-induced depressive-like behaviour and reduces oxidative stress in brain and pancreas

(2015) Gislaine Z. Réus et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

In depressed older persons higher blood pressure is associated with symptoms of apathy. The NESDO study

(2015) J. E. F. Moonen et al.   INTERNATIONAL PSYCHOGERIATRICS

Oxidative Stress and Antioxidant Parameters in Patients With Major Depressive Disorder Compared to Healthy Controls Before and After Antidepressant Treatment

(2015) Sara Jiménez-Fernández et al.   JOURNAL OF CLINICAL PSYCHIATRY

Antidepressive-like effects and antioxidant activity of green tea and GABA green tea in a mouse model of post-stroke depression

(2015) Arianna Di Lorenzo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Markers of Oxidative Stress and Neuroprogression in Depression Disorder

(2015) Magdaléna Vaváková et al.   Oxidative Medicine and Cellular Longevity

Ondansetron attenuates co-morbid depression and anxiety associated with obesity by inhibiting the biochemical alterations and improving serotonergic neurotransmission

(2015) Yeshwant Kurhe et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Role of Translocator Protein Density, a Marker of Neuroinflammation, in the Brain During Major Depressive Episodes

(2015) Elaine Setiawan et al.   JAMA Psychiatry

The link between depression and diabetes: the search for shared mechanisms

(2015) Calum D Moulton et al.   Lancet Diabetes & Endocrinology

The effects of escitalopram on myocardial apoptosis and the expression of Bax and Bcl-2 during myocardial ischemia/reperfusion in a model of rats with depression

(2014) Yiming Wang et al.   BMC Psychiatry

DPP-4 inhibitor linagliptin ameliorates cardiovascular injury in salt-sensitive hypertensive rats independently of blood glucose and blood pressure

(2014) Nobutaka Koibuchi et al.   Cardiovascular Diabetology

Part I: Frequency of Depression after Stroke: An Updated Systematic Review and Meta-Analysis of Observational Studies

(2014) Maree L. Hackett et al.   International Journal of Stroke

Neuropsychiatric outcomes of stroke

(2014) Maree L Hackett et al.   LANCET NEUROLOGY

Resolvin D1, a Metabolite of Omega-3 Polyunsaturated Fatty Acid, Decreases Post-Myocardial Infarct Depression

(2014) Kim Gilbert et al.   Marine Drugs

Melatonin: Exceeding Expectations

(2014) Russel J. Reiter et al.   PHYSIOLOGY

The relationship between obesity and coronary artery disease

(2014) Eiman Jahangir et al.   Translational Research

Link Between Oxidative Stress and Acute Brain Ischemia

(2013) Djordje Radak et al.   ANGIOLOGY

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder

(2013) Elísabet Alcocer-Gómez et al.   BRAIN BEHAVIOR AND IMMUNITY

Natural history, predictors and outcomes of depression after stroke: systematic review and meta-analysis

(2013) Luis Ayerbe et al.   BRITISH JOURNAL OF PSYCHIATRY

Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N=9484)

(2013) M L Molendijk et al.   MOLECULAR PSYCHIATRY

Depression and Risk of Stroke in Midaged Women

(2013) Caroline A. Jackson et al.   STROKE

Trends in Cardiovascular Health Metrics and Associations With All-Cause and CVD Mortality Among US Adults

(2012) Quanhe Yang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Diabetes, hyperglycaemia, and acute ischaemic stroke

(2012) Merel JA Luitse et al.   LANCET NEUROLOGY

Duration of Diabetes and Risk of Ischemic Stroke

(2012) Chirantan Banerjee et al.   STROKE

Invited Commentary: Epidemiologic Studies of the Health Associations of Environmental Exposures With Preterm Birth

(2011) S. L. Zeger   AMERICAN JOURNAL OF EPIDEMIOLOGY

Vascular Mechanisms in the Pathogenesis of Stroke

(2011) Cristina Sierra et al.   CURRENT HYPERTENSION REPORTS

Roles of Oxidative Stress, Apoptosis, PGC-1α and Mitochondrial Biogenesis in Cerebral Ischemia

(2011) Shang-Der Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Depression and Risk of Stroke Morbidity and Mortality

(2011) An Pan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A Prospective Study of Fasting Plasma Glucose and Risk of Stroke in Asymptomatic Men

(2011) Xuemei Sui et al.   MAYO CLINIC PROCEEDINGS

Depression and type 2 diabetes: Inflammatory mechanisms of a psychoneuroendocrine co-morbidity

(2011) Michael J. Stuart et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

(2010) Tetsuro Ago et al.   CIRCULATION RESEARCH

The Use of Statins After a Cardiac Intervention Is Associated With Reduced Risk of Subsequent Depression

(2010) Lesley Stafford et al.   JOURNAL OF CLINICAL PSYCHIATRY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Obesity and Cardiovascular Disease

(2009) Carl J. Lavie et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

“Killing the Blues”: A role for cellular suicide (apoptosis) in depression and the antidepressant response?

(2009) Declan P. McKernan et al.   PROGRESS IN NEUROBIOLOGY

Inhibition of GSK3 differentially modulates NF-κB, CREB, AP-1 and β-catenin signaling in hepatocytes, but fails to promote TNF-α-induced apoptosis

(2008) Frank Götschel et al.   EXPERIMENTAL CELL RESEARCH

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY