Increased 12/15-Lipoxygenase Leads to Widespread Brain Injury Following Global Cerebral Ischemia

Assessment at the Single-Cell Level Identifies Neuronal Glutathione Depletion As Both a Cause and Effect of Ischemia-Reperfusion Oxidative Stress

(2015) S. J. Won et al.   JOURNAL OF NEUROSCIENCE

Lipoxygenase: An Emerging Target for Stroke Therapy

(2013) Klaus van Leyen   CNS & Neurological Disorders-Drug Targets

Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest

(2013) Niklas Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke

(2012) Kazim Yigitkanli et al.   ANNALS OF NEUROLOGY

MicroRNA-223 is neuroprotective by targeting glutamate receptors

(2012) M. M. Harraz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Protease-Activated Receptor-1 in Brain Injury After Experimental Global Cerebral Ischemia

(2012) Jinhu Wang et al.   STROKE

Guidelines for Using Mouse Global Cerebral Ischemia Models

(2012) Tibor Kristian et al.   Translational Stroke Research

Consistent Injury to Medium Spiny Neurons and White Matter in the Mouse Striatum after Prolonged Transient Global Cerebral Ischemia

(2011) Hideyuki Yoshioka et al.   JOURNAL OF NEUROTRAUMA

Role of apoptosis inducing factor (AIF) for hippocampal neuronal cell death following global cerebral ischemia in mice

(2011) Simone E. Thal et al.   NEUROSCIENCE LETTERS

Poly(ADP-Ribose) (PAR) Binding to Apoptosis-Inducing Factor Is Critical for PAR Polymerase-1-Dependent Cell Death (Parthanatos)

(2011) Y. Wang et al.   Science Signaling

Application of Fluoro-Jade C in Acute and Chronic Neurodegeneration Models: Utilities and Staining Differences

(2010) Ayuka Ehara et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Increased Nuclear Apoptosis-Inducing Factor after Transient Focal Ischemia: A 12/15-Lipoxygenase-dependent Organelle Damage Pathway

(2010) Stefanie Pallast et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Characterization of a 3-vessel occlusion model for the induction of complete global cerebral ischemia in mice

(2010) Serge C. Thal et al.   JOURNAL OF NEUROSCIENCE METHODS

AIF: Not Just an Apoptosis-Inducing Factor

(2009) Nicholas Joza et al.   Annals of the New York Academy of Sciences

12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress

(2009) Stefanie Pallast et al.   JOURNAL OF NEUROCHEMISTRY

Green tea polyphenol (-)-epigallocatechin gallate reduces neuronal cell damage and up-regulation of MMP-9 activity in hippocampal CA1 and CA2 areas following transient global cerebral ischemia

(2008) Jong-Wan Park et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Protecting Against Cerebrovascular Injury

(2008) Guang Jin et al.   STROKE

Novel lipoxygenase inhibitors as neuroprotective reagents

(2007) Klaus van Leyen et al.   JOURNAL OF NEUROSCIENCE RESEARCH