- Home
- Publications
- Publication Search
- Publication Details
Title
IL-17 receptor–based signaling and implications for disease
Authors
Keywords
-
Journal
NATURE IMMUNOLOGY
Volume 20, Issue 12, Pages 1594-1602
Publisher
Springer Science and Business Media LLC
Online
2019-11-20
DOI
10.1038/s41590-019-0514-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- PAI-1 augments mucosal damage in colitis
- (2019) Gerard E. Kaiko et al. Science Translational Medicine
- Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses
- (2019) Tzu-Yu Shao et al. Cell Host & Microbe
- Commensal Microbiota Promote Lung Cancer Development via γδ T Cells
- (2019) Chengcheng Jin et al. CELL
- Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans
- (2019) Petra Bacher et al. CELL
- The IL-17 Family of Cytokines in Health and Disease
- (2019) Mandy J. McGeachy et al. IMMUNITY
- IL-17–high asthma with features of a psoriasis immunophenotype
- (2019) Jörgen Östling et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Phosphorylation-dependent Regnase-1 release from endoplasmic reticulum is critical in IL-17 response
- (2019) Hiroki Tanaka et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival
- (2019) Saikat Majumder et al. NATURE IMMUNOLOGY
- Interleukin-17 receptor D constitutes an alternative receptor for interleukin-17A important in psoriasis-like skin inflammation
- (2019) Yang Su et al. Science Immunology
- IL-17 Strikes a Chord in Chronic Obstructive Pulmonary Disease Exacerbation
- (2018) Helen E. Rich et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection
- (2018) Nydiaris Hernández-Santos et al. Cell Host & Microbe
- RNA-Targeted Therapeutics
- (2018) Stanley T. Crooke et al. Cell Metabolism
- Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells
- (2018) Yu Zhang et al. GASTROENTEROLOGY
- Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A
- (2018) Mingchao Wang et al. IMMUNITY
- TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis
- (2018) Ramesh Singh et al. JOURNAL OF CLINICAL INVESTIGATION
- IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling
- (2018) Tomasz Herjan et al. NATURE IMMUNOLOGY
- Vaccination with an alkaline extract of Histoplasma capsulatum packaged in glucan particles confers protective immunity in mice
- (2018) George S. Deepe et al. VACCINE
- An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup
- (2018) Stephanie A. Christenson et al. JOURNAL OF CLINICAL INVESTIGATION
- IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells
- (2018) Xing Chen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TRAF4 binds to the juxtamembrane region of EGFR directly and promotes kinase activation
- (2018) Gang Cai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a
- (2018) Nilesh Amatya et al. Science Signaling
- Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression
- (2018) Arianna Calcinotto et al. Nature Communications
- Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation
- (2017) Tao Peng et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-17A–Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis
- (2017) Jarod A. Zepp et al. JOURNAL OF IMMUNOLOGY
- Mucocutaneous IL-17 immunity in mice and humans: host defense vs. excessive inflammation
- (2017) J Li et al. Mucosal Immunology
- IL-17 Signaling: The Yin and the Yang
- (2017) Nilesh Amatya et al. TRENDS IN IMMUNOLOGY
- IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression
- (2017) Chenhui Wang et al. Nature Communications
- Pneumocystis -Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity
- (2017) Taylor Eddens et al. Cell Reports
- Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma
- (2017) Evelyn Santos Guerra et al. PLoS Pathogens
- IL17 factors are early regulators in the gut epithelium during inflammatory response to Vibrio in the sea urchin larva
- (2017) Katherine M Buckley et al. eLife
- FGF2 cooperates with IL-17 to promote autoimmune inflammation
- (2017) Xinrui Shao et al. Scientific Reports
- MCPIP1/Regnase-1 Restricts IL-17A– and IL-17C–Dependent Skin Inflammation
- (2016) Leticia Monin et al. JOURNAL OF IMMUNOLOGY
- Antibody blockade of IL-17 family cytokines in immunity to acute murine oral mucosal candidiasis
- (2016) Natasha Whibley et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Sequential Dysfunction and Progressive Depletion of Candida albicans-Specific CD4 T Cell Response in HIV-1 Infection
- (2016) Fengliang Liu et al. PLoS Pathogens
- ERK5 Is a Critical Mediator of Inflammation-Driven Cancer
- (2015) K. G. Finegan et al. CANCER RESEARCH
- Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms
- (2015) Takashi Mino et al. CELL
- Interleukin-17A Plays a Pivotal Role in Chemically Induced Hepatocellular Carcinoma in Mice
- (2015) Chao Sun et al. DIGESTIVE DISEASES AND SCIENCES
- Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage
- (2015) Xinyang Song et al. IMMUNITY
- Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation
- (2015) Natalia B. Pikor et al. IMMUNITY
- MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation
- (2015) Abhishek V. Garg et al. IMMUNITY
- Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation
- (2015) Joseph R. Maxwell et al. IMMUNITY
- A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4–ERK5 axis
- (2015) Ling Wu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis
- (2015) Yun Ling et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CIKS/DDX3X Interaction Controls the Stability of theZc3h12amRNA Induced by IL-17
- (2015) Domenico Somma et al. JOURNAL OF IMMUNOLOGY
- The miR-30a Negatively Regulates IL-17-Mediated Signal Transduction by Targeting Traf3ip2
- (2015) Qun Wan et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Syk Mediates IL−17-Induced CCL20 Expression by Targeting Act1-Dependent K63-Linked Ubiquitination of TRAF6
- (2015) Nan-Lin Wu et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis
- (2015) Seth B. Coffelt et al. NATURE
- IκBζ is a key driver in the development of psoriasis
- (2015) Claus Johansen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3β-C/EBPβ pathway
- (2015) Tomoki Maekawa et al. Nature Communications
- Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis
- (2014) Kepeng Wang et al. IMMUNITY
- The Human IL-17F/IL-17A Heterodimeric Cytokine Signals through the IL-17RA/IL-17RC Receptor Complex
- (2014) J. F. Wright et al. JOURNAL OF IMMUNOLOGY
- TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice
- (2014) L. McKinley et al. JOURNAL OF IMMUNOLOGY
- Post-transcriptional coordination of immunological responses by RNA-binding proteins
- (2014) Panagiota Kafasla et al. NATURE IMMUNOLOGY
- Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials
- (2014) Richard G. Langley et al. NEW ENGLAND JOURNAL OF MEDICINE
- IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms
- (2014) H.-L. Ha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unexpected Role for IL-17 in Protective Immunity against Hypervirulent Mycobacterium tuberculosis HN878 Infection
- (2014) Radha Gopal et al. PLoS Pathogens
- An ACT1 Mutation Selectively Abolishes Interleukin-17 Responses in Humans with Chronic Mucocutaneous Candidiasis
- (2013) Bertrand Boisson et al. IMMUNITY
- Mechanisms underlying helper T-cell plasticity: Implications for immune-mediated disease
- (2013) Kiyoshi Hirahara et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Crystal Structure of IL-17 Receptor B SEFIR Domain
- (2013) B. Zhang et al. JOURNAL OF IMMUNOLOGY
- HuR Is Required for IL-17-Induced Act1-Mediated CXCL1 and CXCL5 mRNA Stabilization
- (2013) T. Herjan et al. JOURNAL OF IMMUNOLOGY
- An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
- (2013) Alicia S Chung et al. NATURE MEDICINE
- Act1 mediates IL-17–induced EAE pathogenesis selectively in NG2+ glial cells
- (2013) Zizhen Kang et al. NATURE NEUROSCIENCE
- The Anaphase-Promoting Complex Protein 5 (AnapC5) Associates with A20 and Inhibits IL-17-Mediated Signal Transduction
- (2013) Allen W. Ho et al. PLoS One
- STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor
- (2013) Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Deubiquitinase A20 Mediates Feedback Inhibition of Interleukin-17 Receptor Signaling
- (2013) A. V. Garg et al. Science Signaling
- TRAF4 Is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell Migration
- (2013) Adrien Rousseau et al. PLOS BIOLOGY
- The Antimicrobial Protein REG3A Regulates Keratinocyte Proliferation and Differentiation after Skin Injury
- (2012) Yuping Lai et al. IMMUNITY
- Cutting Edge: TNF Receptor-Associated Factor 4 Restricts IL-17-Mediated Pathology and Signaling Processes
- (2012) J. A. Zepp et al. JOURNAL OF IMMUNOLOGY
- Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
- (2012) Vivian W. Y. Wong et al. NATURE CELL BIOLOGY
- The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90
- (2012) Chenhui Wang et al. NATURE IMMUNOLOGY
- Negative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25
- (2012) Bo Zhong et al. NATURE IMMUNOLOGY
- The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α
- (2012) Shu Zhu et al. NATURE MEDICINE
- Targeting IL-17 and TH17 cells in chronic inflammation
- (2012) Pierre Miossec et al. NATURE REVIEWS DRUG DISCOVERY
- Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis
- (2012) Craig Leonardi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation
- (2011) Anneli Peters et al. IMMUNITY
- Vaccine Immunity to Coccidioidomycosis Occurs by Early Activation of Three Signal Pathways of T Helper Cell Response (Th1, Th2, and Th17)
- (2011) Chiung-Yu Hung et al. INFECTION AND IMMUNITY
- IL-17-induced NF-κB Activation via CIKS/Act1
- (2011) Søren Ulrik Sønder et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice
- (2011) Marcel Wüthrich et al. JOURNAL OF CLINICAL INVESTIGATION
- Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)
- (2011) Dongxu Sun et al. NATURE IMMUNOLOGY
- The development of inducible bronchus-associated lymphoid tissue depends on IL-17
- (2011) Javier Rangel-Moreno et al. NATURE IMMUNOLOGY
- The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation
- (2011) Katarzyna Bulek et al. NATURE IMMUNOLOGY
- Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity
- (2011) A. Puel et al. SCIENCE
- Persistent Stimulation with Interleukin-17 Desensitizes Cells Through SCF -TrCP-Mediated Degradation of Act1
- (2011) P. Shi et al. Science Signaling
- IL-17 Enhances Tumor Development in Carcinogen-Induced Skin Cancer
- (2010) L. Wang et al. CANCER RESEARCH
- Increased IL-17A secretion in response to Candida albicans in autoimmune polyendocrine syndrome type 1 and its animal model
- (2010) Kerstin M. Ahlgren et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- SEF/IL-17R (SEFIR) Is Not Enough
- (2010) Reiko M. Onishi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Induction of Neutrophil Gelatinase-associated Lipocalin Expression by Co-stimulation with Interleukin-17 and Tumor Necrosis Factor-α Is Controlled by IκB-ζ but neither by C/EBP-β nor C/EBP-δ
- (2010) Joachim R. Karlsen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling
- (2010) Shu Zhu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-17RC Is Required for Immune Signaling via an Extended SEF/IL-17R Signaling Domain in the Cytoplasmic Tail
- (2010) A. W. Ho et al. JOURNAL OF IMMUNOLOGY
- Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
- (2010) W. Hueber et al. Science Translational Medicine
- Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
- (2009) Ivaylo I. Ivanov et al. CELL
- IL-17 Receptor Signaling Inhibits C/EBP by Sequential Phosphorylation of the Regulatory 2 Domain
- (2009) F. Shen et al. Science Signaling
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started