Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma

Asthma phenotypes and endotypes

(2016) Gwen S. Skloot   CURRENT OPINION IN PULMONARY MEDICINE

Small intestinal eosinophils regulate Th17 cells by producing IL-1 receptor antagonist

(2016) Reiko Sugawara et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Development of the CRISPR/Cas9 System for Targeted Gene Disruption in Aspergillus fumigatus

(2015) Kevin K. Fuller et al.   EUKARYOTIC CELL

Immune Interactions with Pathogenic and Commensal Fungi: A Two-Way Street

(2015) David M. Underhill et al.   IMMUNITY

Prime role of IL-17A in neutrophilia and airway smooth muscle contraction in a house dust mite–induced allergic asthma model

(2015) Julie Chesné et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Eosinophils in mucosal immune responses

(2015) J Travers et al.   Mucosal Immunology

The immunology of asthma

(2015) Bart N Lambrecht et al.   NATURE IMMUNOLOGY

IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases

(2015) Michele W L Teng et al.   NATURE MEDICINE

Basic biology and role of interleukin-17 in immunity and inflammation

(2015) Camille Zenobia et al.   PERIODONTOLOGY 2000

Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts

(2015) Charles A. Specht et al.   mBio

Recognition of Aspergillus fumigatus Hyphae by Human Plasmacytoid Dendritic Cells Is Mediated by Dectin-2 and Results in Formation of Extracellular Traps

(2015) Flávio V. Loures et al.   PLoS Pathogens

Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection

(2015) Darin L. Wiesner et al.   PLoS Pathogens

Compartment-Specific and Sequential Role of MyD88 and CARD9 in Chemokine Induction and Innate Defense during Respiratory Fungal Infection

(2015) Anupam Jhingran et al.   PLoS Pathogens

IL-17 in Severe Asthma. Where Do We Stand?

(2014) Julie Chesné et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Eosinophil–Epithelial Cell Interactions Stimulate the Production of MUC5AC Mucin and Profibrotic Cytokines Involved in Airway Tissue Remodeling

(2014) Shino Shimizu et al.   American Journal of Rhinology & Allergy

Changing roles of eosinophils in health and disease

(2014) Glenn T. Furuta et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Potential role of myeloid cell/eosinophil-derived IL-17 in LPS-induced endotoxin shock

(2014) Eri Shimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Re-defining the unique roles for eosinophils in allergic respiratory inflammation

(2014) E. A. Jacobsen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Eosinophils Are Recruited in Response to Chitin Exposure and Enhance Th2-Mediated Immune Pathology in Aspergillus fumigatus Infection

(2014) Evan M. O'Dea et al.   INFECTION AND IMMUNITY

IL-17-Producing Alveolar Macrophages Mediate Allergic Lung Inflammation Related to Asthma

(2014) C. Song et al.   JOURNAL OF IMMUNOLOGY

Functionally Competent Eosinophils Differentiated Ex Vivo in High Purity from Normal Mouse Bone Marrow

(2014) K. D. Dyer et al.   JOURNAL OF IMMUNOLOGY

Multi-Country Estimate of Different Manifestations of Aspergillosis in Cystic Fibrosis

(2014) Joanne Armstead et al.   PLoS One

Myeloid Derived Hypoxia Inducible Factor 1-alpha Is Required for Protection against Pulmonary Aspergillus fumigatus Infection

(2014) Kelly M. Shepardson et al.   PLoS Pathogens

Inflammatory Monocytes Orchestrate Innate Antifungal Immunity in the Lung

(2014) Vanessa Espinosa et al.   PLoS Pathogens

Eosinophil Deficiency Compromises Lung Defense against Aspergillus fumigatus

(2013) Lauren M. Lilly et al.   INFECTION AND IMMUNITY

Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2

(2013) Patricia R Taylor et al.   NATURE IMMUNOLOGY

Strain Dependent Variation of Immune Responses to A. fumigatus: Definition of Pathogenic Species

(2013) Lisa Rizzetto et al.   PLoS One

Aspergillus fumigatus—What Makes the Species a Ubiquitous Human Fungal Pathogen?

(2013) Kyung J. Kwon-Chung et al.   PLoS Pathogens

Interleukin-17 Drives Pulmonary Eosinophilia following Repeated Exposure to Aspergillus fumigatus Conidia

(2012) Benjamin J. Murdock et al.   INFECTION AND IMMUNITY

Human versus mouse eosinophils: “That which we call an eosinophil, by any other name would stain as red”

(2012) James J. Lee et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Fungi and allergic lower respiratory tract diseases

(2012) Alan P. Knutsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults

(2012) David W. Denning et al.   MEDICAL MYCOLOGY

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Tracing Conidial Fate and Measuring Host Cell Antifungal Activity Using a Reporter of Microbial Viability in the Lung

(2012) Anupam Jhingran et al.   Cell Reports

Biosynthesis and function of gliotoxin in Aspergillus fumigatus

(2011) Daniel H. Scharf et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

TH17 cells in asthma and inflammation

(2011) Shean J. Aujla et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A Nonredundant Role for Plasmacytoid Dendritic Cells in Host Defense against the Human Fungal Pathogen Aspergillus fumigatus

(2011) Zaida G. Ramirez-Ortiz et al.   Cell Host & Microbe

Functional Specialization of Interleukin-17 Family Members

(2011) Yoichiro Iwakura et al.   IMMUNITY

Insights into human antifungal immunity from primary immunodeficiencies

(2011) Donald C Vinh   LANCET INFECTIOUS DISEASES

Contributions of the MyD88-Dependent Receptors IL-18R, IL-1R, and TLR9 to Host Defenses following Pulmonary Challenge with Cryptococcus neoformans

(2011) Jennifer P. Wang et al.   PLoS One

Eosinophils and Th2 immunity: contemporary insights

(2010) Lisa A Spencer et al.   IMMUNOLOGY AND CELL BIOLOGY

Antiviral CD8+T cell effector activities in situ are regulated by target cell type

(2010) Matthew M. Hufford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Eosinophils Recognize Endogenous Danger Signal Crystalline Uric Acid and Produce Proinflammatory Cytokines Mediated by Autocrine ATP

(2010) T. Kobayashi et al.   JOURNAL OF IMMUNOLOGY

Innate Immunity to Aspergillus Species

(2009) S. J. Park et al.   CLINICAL MICROBIOLOGY REVIEWS

Requisite Role for the Dectin-1  -Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus

(2009) J. L. Werner et al.   JOURNAL OF IMMUNOLOGY

Modulation of Exaggerated-IgE Allergic Responses by Gene Transfer-mediated Antagonism of IL-13 and IL-17e

(2009) Christian Mueller et al.   MOLECULAR THERAPY

Mouse models of allergic asthma: acute and chronic allergen challenge

(2008) A. T. Nials et al.   Disease Models & Mechanisms

Differences in pathogenicity and clinical syndromes due toAspergillus fumigatusandAspergillus flavus

(2008) Alessandro C. Pasqualotto   MEDICAL MYCOLOGY