Antibody blockade of IL-17 family cytokines in immunity to acute murine oral mucosal candidiasis

Orosomucoid 1 drives opportunistic infections through the polarization of monocytes to the M2b phenotype

(2015) Kiwamu Nakamura et al.   CYTOKINE

Secukinumab: First Global Approval

(2015) Mark Sanford et al.   DRUGS

Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis

(2015) Kristian Reich et al.   EXPERIMENTAL DERMATOLOGY

Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis

(2015) Yun Ling et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Orosomucoid, an acute response protein with multiple modulating activities

(2015) Zhumin Luo et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Signaling through IL-17C/IL-17RE Is Dispensable for Immunity to Systemic, Oral and Cutaneous Candidiasis

(2015) Heather R. Conti et al.   PLoS One

Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

(2015) S. Okada et al.   SCIENCE

Oral-resident natural Th17 cells and γδ T cells control opportunisticCandida albicansinfections

(2014) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Human IL-17F/IL-17A Heterodimeric Cytokine Signals through the IL-17RA/IL-17RC Receptor Complex

(2014) J. F. Wright et al.   JOURNAL OF IMMUNOLOGY

The Adaptor Protein CIKS/Act1 Is Essential for IL-25-Mediated Allergic Airway Inflammation

(2014) E. Claudio et al.   JOURNAL OF IMMUNOLOGY

IL-17-mediated antifungal defense in the oral mucosa is independent of neutrophils

(2014) K Trautwein-Weidner et al.   Mucosal Immunology

Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials

(2014) Richard G. Langley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of Keratinocyte Differentiation by the Synergistic Effect of IL-17A, IL-22, IL-1α, TNFα and Oncostatin M

(2014) Hanitriniaina Rabeony et al.   PLoS One

An ACT1 Mutation Selectively Abolishes Interleukin-17 Responses in Humans with Chronic Mucocutaneous Candidiasis

(2013) Bertrand Boisson et al.   IMMUNITY

Interleukin-17-Induced Protein Lipocalin 2 Is Dispensable for Immunity to Oral Candidiasis

(2013) Maria Carolina Ferreira et al.   INFECTION AND IMMUNITY

Effect of IL-17A blockade with secukinumab in autoimmune diseases

(2012) Dhavalkumar D Patel et al.   ANNALS OF THE RHEUMATIC DISEASES

Cutting Edge: IL-17-Secreting Innate Lymphoid Cells Are Essential for Host Defense against Fungal Infection

(2012) A. Gladiator et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Nlrp10 Is Essential for Protective Antifungal Adaptive Immunity against Candida albicans

(2012) S. Joly et al.   JOURNAL OF IMMUNOLOGY

A Novel Th Cell Epitope of Candida albicans Mediates Protection from Fungal Infection

(2012) E. Bar et al.   JOURNAL OF IMMUNOLOGY

Th17 cells confer long-term adaptive immunity to oral mucosal Candida albicans infections

(2012) N Hernández-Santos et al.   Mucosal Immunology

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

Mouse model of oropharyngeal candidiasis

(2012) Norma V Solis et al.   Nature Protocols

Targeting IL-17 and TH17 cells in chronic inflammation

(2012) Pierre Miossec et al.   NATURE REVIEWS DRUG DISCOVERY

Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis

(2012) Kim A. Papp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

(2012) Craig Leonardi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

(2012) I. D. Iliev et al.   SCIENCE

Mucocutaneous candidiasis: the IL-17 pathway and implications for targeted immunotherapy

(2012) Anna R Huppler et al.   ARTHRITIS RESEARCH & THERAPY

Mucosal Immunity andCandida albicansInfection

(2011) David L. Moyes et al.   Clinical & Developmental Immunology

Functional Specialization of Interleukin-17 Family Members

(2011) Yoichiro Iwakura et al.   IMMUNITY

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

Chronic mucocutaneous candidiasis and congenital susceptibility to Candida

(2010) Erik Glocker et al.   Current Opinion in Allergy and Clinical Immunology

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease

(2010) Reiko M. Onishi et al.   IMMUNOLOGY

Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

(2010) Anne Puel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

(2010) Kai Kisand et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17RC Is Required for Immune Signaling via an Extended SEF/IL-17R Signaling Domain in the Cytoplasmic Tail

(2010) A. W. Ho et al.   JOURNAL OF IMMUNOLOGY

IL-23 and IL-17A, but Not IL-12 and IL-22, Are Required for Optimal Skin Host Defense against Candida albicans

(2010) S. Kagami et al.   JOURNAL OF IMMUNOLOGY

Innate immune mechanisms for recognition and uptake of Candida species

(2010) Mihai G. Netea et al.   TRENDS IN IMMUNOLOGY

Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses

(2009) Harumichi Ishigame et al.   IMMUNITY

Th17 cytokines and their emerging roles in inflammation and autoimmunity

(2009) Lynette A. Fouser et al.   IMMUNOLOGICAL REVIEWS

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

(2009) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17A Controls IL-17F Production and Maintains Blood Neutrophil Counts in Mice

(2009) S. von Vietinghoff et al.   JOURNAL OF IMMUNOLOGY

Structural basis of receptor sharing by interleukin 17 cytokines

(2009) Lauren K Ely et al.   NATURE IMMUNOLOGY

Genetic origins of hyper-IgE syndrome

(2008) Yoshiyuki Minegishi et al.   CURRENT ALLERGY AND ASTHMA REPORTS

STAT3 single-nucleotide polymorphisms and STAT3 mutations associated with hyper-IgE syndrome are not responsible for increased serum IgE serum levels in asthma families

(2008) Matthias Wjst et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The Hyper-IgE Syndromes

(2008) Alexandra F. Freeman et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Defects in Jak-STAT-mediated cytokine signals cause hyper-IgE syndrome: lessons from a primary immunodeficiency

(2008) Y. Minegishi et al.   INTERNATIONAL IMMUNOLOGY

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced TH17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

(2008) Ellen D. Renner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE