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Asparagine-linked glycosylation modifies voltage-dependent gating properties of CaV3.1-T-type Ca2+ channel

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Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA

(2019) Xiaojing Pan et al.   SCIENCE

Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins

(2019) Huaizong Shen et al.   SCIENCE

The T‐type calcium channel blocker Z944 reduces conditioned fear in Genetic Absence Epilepsy Rats from Strasbourg and the Non‐Epileptic Control strain

(2019) Wendie N. Marks et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+ Channel

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Modulation of cardiac ryanodine receptor 2 by calmodulin

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De novo mutation screening in childhood-onset cerebellar atrophy identifies gain-of-function mutations in the CACNA1G calcium channel gene

(2018) Jean Chemin et al.   BRAIN

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(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs

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Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1

(2018) Xiaojing Pan et al.   SCIENCE

T-type calcium channel blockers: a patent review (2012–2018)

(2018) Ghilsoo Nam   EXPERT OPINION ON THERAPEUTIC PATENTS

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

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(2017) Shawn Q Zheng et al.   NATURE METHODS

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(2017) Emmanuel Bourinet et al.   NEUROPHARMACOLOGY

Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution

(2017) Huaizong Shen et al.   SCIENCE

Modulation of Cav3.2 T-type calcium channel permeability by asparagine-linked glycosylation

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(2016) Annette C. Dolphin   JOURNAL OF PHYSIOLOGY-LONDON

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution

(2016) Jianping Wu et al.   NATURE

T-type calcium channel blocker Z944 restores cortical synchrony and thalamocortical connectivity in a rat model of neuropathic pain

(2016) Brian W. LeBlanc et al.   PAIN

Cooperative roles of glucose and asparagine-linked glycosylation in T-type calcium channel expression

(2016) Joanna Lazniewska et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

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CACNA1H Mutations Are Associated With Different Forms of Primary Aldosteronism

(2016) Georgios Daniil et al.   EBioMedicine

A Recurrent Mutation in CACNA1G Alters Cav3.1 T-Type Calcium-Channel Conduction and Causes Autosomal-Dominant Cerebellar Ataxia

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Targeting voltage-gated calcium channels in neurological and psychiatric diseases

(2015) Gerald W. Zamponi   NATURE REVIEWS DRUG DISCOVERY

Structure of the voltage-gated calcium channel Cav1.1 complex

(2015) J. Wu et al.   SCIENCE

A mutation in the low voltage-gated calcium channel CACNA1G alters the physiological properties of the channel, causing spinocerebellar ataxia

(2015) Hiroyuki Morino et al.   Molecular Brain

Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism

(2015) Ute I Scholl et al.   eLife

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

Z944, a Novel Selective T-Type Calcium Channel Antagonist Delays the Progression of Seizures in the Amygdala Kindling Model

(2015) Pablo Miguel Casillas-Espinosa et al.   PLoS One

Z944: A first in class T-type calcium channel modulator for the treatment of pain

(2014) M Lee   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Structure of the Yeast Mitochondrial Large Ribosomal Subunit

(2014) A. Amunts et al.   SCIENCE

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Surface expression and function of Cav3.2 T-type calcium channels are controlled by asparagine-linked glycosylation

(2013) Norbert Weiss et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

T-Type Calcium Channel Blockers That Attenuate Thalamic Burst Firing and Suppress Absence Seizures

(2012) E. Tringham et al.   Science Translational Medicine

Features and development ofCoot

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A Gating Charge Transfer Center in Voltage Sensors

(2010) X. Tao et al.   SCIENCE

Alternative splicing within the I-II loop controls surface expression of T-type Cav3.1 calcium channels

(2008) Aleksandr Shcheglovitov et al.   FEBS LETTERS

Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels

(2007) Christopher A. Ahern et al.   CIRCULATION RESEARCH