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Title
T-type calcium channel blockers: a patent review (2012–2018)
Authors
Keywords
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Journal
EXPERT OPINION ON THERAPEUTIC PATENTS
Volume 28, Issue 12, Pages 883-901
Publisher
Informa UK Limited
Online
2018-10-30
DOI
10.1080/13543776.2018.1541982
References
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Related references
Note: Only part of the references are listed.- Efficacy and safety of a T-type calcium channel blocker in patients with neuropathic pain: A proof-of-concept, randomized, double-blind and controlled trial
- (2018) N. Kerckhove et al. EUROPEAN JOURNAL OF PAIN
- Synthesis of new N3- substituted dihydropyrimidine derivatives as L-/T- type calcium channel blockers
- (2017) Mohamed Teleb et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Otoprotective effects of ethosuximide in NOD/LtJ mice with age-related hearing loss
- (2017) Lu Sang et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Discovery of a Potent, Selective T-type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies
- (2017) Olivier Bezençon et al. JOURNAL OF MEDICINAL CHEMISTRY
- Calcium-channel blockers as therapeutic agents for acquired sensorineural hearing loss
- (2017) James G. Naples MEDICAL HYPOTHESES
- Lack of Antiparkinsonian Effects of Systemic Injections of the Specific T-Type Calcium Channel Blocker ML218 in MPTP-Treated Monkeys
- (2016) Adriana Galvan et al. ACS Chemical Neuroscience
- Synthesis and evaluation of 6-pyrazoylamido-3 N -substituted azabicyclo[3,1,0]hexane derivatives as T-type calcium channel inhibitors for treatment of neuropathic pain
- (2016) Jung Hyun Kim et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and T-type calcium channel-blocking effects of aryl(1,5-disubstituted-pyrazol-3-yl)methyl sulfonamides for neuropathic pain treatment
- (2016) Jung Hyun Kim et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Anatomical localization of Cav3.1 calcium channels and electrophysiological effects of T-type calcium channel blockade in the motor thalamus of MPTP-treated monkeys
- (2016) Annaelle Devergnas et al. JOURNAL OF NEUROPHYSIOLOGY
- T-type calcium channels in neuropathic pain
- (2016) Emmanuel Bourinet et al. PAIN
- Protection of the cochlear hair cells in adult C57BL/6J mice by T-type calcium channel blockers
- (2016) YA-FENG YU et al. Experimental and Therapeutic Medicine
- Targeting voltage-gated calcium channels in neurological and psychiatric diseases
- (2015) Gerald W. Zamponi NATURE REVIEWS DRUG DISCOVERY
- Optimization of ADME Properties for Sulfonamides Leading to the Discovery of a T-Type Calcium Channel Blocker, ABT-639
- (2015) Qingwei Zhang et al. ACS Medicinal Chemistry Letters
- Characterization of Novel Cannabinoid Based T-Type Calcium Channel Blockers with Analgesic Effects
- (2014) Chris Bladen et al. ACS Chemical Neuroscience
- Synthesis and biological evaluation of 1-(isoxazol-5-ylmethylaminoethyl)-4-phenyl tetrahydropyridine and piperidine derivatives as potent T-type calcium channel blockers with antinociceptive effect in a neuropathic pain model
- (2014) Ju-Hyeon Lee et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and biological evaluation of 1-(2-hydroxy-3-phenyloxypropyl)piperazine derivatives as T-type calcium channel blockers
- (2013) Jung-eun Park et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Randomized controlled study of the T-type calcium channel antagonist MK-8998 for the treatment of acute psychosis in patients with schizophrenia
- (2013) Michael F. Egan et al. HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
- Analgesic Effect of a Mixed T-Type Channel Inhibitor/CB2 Receptor Agonist
- (2013) Vinicius M Gadotti et al. Molecular Pain
- Functional Characterization and Analgesic Effects of Mixed Cannabinoid Receptor/T-Type Channel Ligands
- (2012) Haitao You et al. Molecular Pain
- T-Type Calcium Channel as a New Therapeutic Target for Tremor
- (2011) Hideto Miwa et al. CEREBELLUM
- T-type calcium channels inhibitors: a patent review
- (2010) Fabrizio Giordanetto et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Effects of T-type calcium channel blockers on a parkinsonian tremor model in rats
- (2010) Hideto Miwa et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Discovery of 1,4-Substituted Piperidines as Potent and Selective Inhibitors of T-Type Calcium Channels
- (2008) Zhi-Qiang Yang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Regulation of neuronal T-type calcium channels
- (2008) Mircea C. Iftinca et al. TRENDS IN PHARMACOLOGICAL SCIENCES
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