Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E

DBC2/RhoBTB2 functions as a tumor suppressor protein via Musashi-2 ubiquitination in breast cancer

(2016) Y M Choi et al.   ONCOGENE

Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors

(2015) Stella-Rita C. Ibeawuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Why Are the Truncated Cyclin Es More Effective CDK2 Activators than the Full-Length Isoforms?

(2014) Soumya Lipsa Rath et al.   BIOCHEMISTRY

Novel Cul3 binding proteins function to remodel E3 ligase complexes

(2014) Wananit Wimuttisuk et al.   BMC CELL BIOLOGY

Destruction of DDIT3/CHOP Protein by Wild-Type SPOP but Not Prostate Cancer-Associated Mutants

(2014) Pingzhao Zhang et al.   HUMAN MUTATION

Hyperkalemic hypertension–associated cullin 3 promotes WNK signaling by degrading KLHL3

(2014) James A. McCormick et al.   JOURNAL OF CLINICAL INVESTIGATION

Golgi-associated RhoBTB3 targets Cyclin E for ubiquitylation and promotes cell cycle progression

(2013) Albert Lu et al.   JOURNAL OF CELL BIOLOGY

Fbw7  and Fbw7  Collaborate To Shuttle Cyclin E1 into the Nucleolus for Multiubiquitylation

(2012) N. Bhaskaran et al.   MOLECULAR AND CELLULAR BIOLOGY

Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities

(2012) Lynn M. Boyden et al.   NATURE

LMW-E/CDK2 Deregulates Acinar Morphogenesis, Induces Tumorigenesis, and Associates with the Activated b-Raf-ERK1/2-mTOR Pathway in Breast Cancer Patients

(2012) MyLinh T. Duong et al.   PLoS Genetics

Low Molecular Weight Cyclin E Overexpression Shortens Mitosis, Leading to Chromosome Missegregation and Centrosome Amplification

(2010) Rozita Bagheri-Yarmand et al.   CANCER RESEARCH

PEST sequences mediate heat shock factor 2 turnover by interacting with the Cul3 subunit of the Cul3-RING ubiquitin ligase

(2010) Hongyan Xing et al.   CELL STRESS & CHAPERONES

Low-Molecular-Weight Cyclin E Can Bypass Letrozole-Induced G1 Arrest in Human Breast Cancer Cells and Tumors

(2010) S. Akli et al.   CLINICAL CANCER RESEARCH

Altered Subcellular Localization of Tumor-Specific Cyclin E Isoforms Affects Cyclin-Dependent Kinase 2 Complex Formation and Proteasomal Regulation

(2009) N. A. Delk et al.   CANCER RESEARCH

The Cul3/Klhdc5 E3 Ligase Regulates p60/Katanin and Is Required for Normal Mitosis in Mammalian Cells

(2009) Cristina M. Cummings et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cullin Mediates Degradation of RhoA through Evolutionarily Conserved BTB Adaptors to Control Actin Cytoskeleton Structure and Cell Movement

(2009) Yuezhou Chen et al.   MOLECULAR CELL

Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation

(2008) David M. Duda et al.   CELL

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo

(2008) A. C. Minella et al.   GENES & DEVELOPMENT