Fbw7  and Fbw7  Collaborate To Shuttle Cyclin E1 into the Nucleolus for Multiubiquitylation

Negative Regulation of the Stability and Tumor Suppressor Function of Fbw7 by the Pin1 Prolyl Isomerase

(2012) Sang-Hyun Min et al.   MOLECULAR CELL

Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma

(2012) Luca Busino et al.   NATURE CELL BIOLOGY

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway

(2012) Azadeh Arabi et al.   Nature Communications

SCFFbw7 Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction

(2012) Hidefumi Fukushima et al.   Cell Reports

Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress

(2011) Akinobu Matsumoto et al.   CANCER SCIENCE

Both SCFCdc4αand SCFCdc4γare required for cyclin E turnover in cell lines that don’t overexpress cyclin E

(2011) Olle Sangfelt et al.   CELL CYCLE

Nucleolar Targeting of the Fbw7 Ubiquitin Ligase by a Pseudosubstrate and Glycogen Synthase Kinase 3

(2011) M. Welcker et al.   MOLECULAR AND CELLULAR BIOLOGY

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

(2011) Hiroyuki Inuzuka et al.   NATURE

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

(2011) Ingrid E. Wertz et al.   NATURE

Nucleolar targeting: the hub of the matter

(2009) Edward Emmott et al.   EMBO REPORTS

SCFFbxw7/hCdc4 targets cyclin E2 for ubiquitin-dependent proteolysis

(2008) Kathleen Klotz et al.   EXPERIMENTAL CELL RESEARCH

SCFCdc4 acts antagonistically to the PGC-1  transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis

(2008) B. L. Olson et al.   GENES & DEVELOPMENT

Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7γ

(2008) Paola Bonetti et al.   JOURNAL OF CELL BIOLOGY

Isoform- and cell cycle–dependent substrate degradation by the Fbw7 ubiquitin ligase

(2008) Jonathan E. Grim et al.   JOURNAL OF CELL BIOLOGY