No evidence of Gremlin1-mediated activation of VEGFR2 signaling in endothelial cells

Gremlin activates the Notch pathway linked to renal inflammation

(2018) Carolina Lavoz et al.   CLINICAL SCIENCE

Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein–Gremlin signaling pathways

(2018) Kathleen E. Tumelty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis

(2018) Laura Marquez-Exposito et al.   Frontiers in Pharmacology

Prognostic significance of stromal GREM1 expression in colorectal cancer

(2017) Bo Gun Jang et al.   HUMAN PATHOLOGY

A functional variant in GREM1 confers risk for colorectal cancer by disrupting a hsa-miR-185-3p binding site

(2017) Jiaoyuan Li et al.   Oncotarget

Gremlin-1 is a key regulator of the invasive cell phenotype in mesothelioma

(2017) Miao Yin et al.   Oncotarget

Endothelial Progenitors: A Consensus Statement on Nomenclature

(2017) Reinhold J. Medina et al.   Stem Cells Translational Medicine

GREM1 Is a Key Regulator of Synoviocyte Hyperplasia and Invasiveness

(2016) E.-J. Han et al.   JOURNAL OF RHEUMATOLOGY

Bone Morphogenetic Proteins

(2016) Takenobu Katagiri et al.   Cold Spring Harbor Perspectives in Biology

Monomeric gremlin is a novel vascular endothelial growth factor receptor-2 antagonist

(2016) Elisabetta Grillo et al.   Oncotarget

Gremlin inhibits UV-induced skin cell damages via activating VEGFR2-Nrf2 signaling

(2016) Chao Ji et al.   Oncotarget

Gremlin promotes retinal pigmentation epithelial (RPE) cell proliferation, migration and VEGF production via activating VEGFR2-Akt-mTORC2 signaling

(2016) Yuan Liu et al.   Oncotarget

Bone morphogenetic protein antagonist gremlin-1 regulates colon cancer progression

(2015) George S. Karagiannis et al.   BIOLOGICAL CHEMISTRY

Gremlin is a key pro-fibrogenic factor in chronic pancreatitis

(2015) Dustin Staloch et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

BMP signalling: agony and antagony in the family

(2015) Derek P. Brazil et al.   TRENDS IN CELL BIOLOGY

Site-Specific Phosphorylation of VEGFR2 Is Mediated by Receptor Trafficking: Insights from a Computational Model

(2015) Lindsay Wendel Clegg et al.   PLoS Computational Biology

Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy

(2014) K. Yan et al.   GENES & DEVELOPMENT

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

(2014) Hayley Davis et al.   NATURE MEDICINE

A Polymorphic Enhancer near GREM1 Influences Bowel Cancer Risk through Differential CDX2 and TCF7L2 Binding

(2014) Annabelle Lewis et al.   Cell Reports

Gremlin Activates the Smad Pathway Linked to Epithelial Mesenchymal Transdifferentiation in Cultured Tubular Epithelial Cells

(2014) Raquel Rodrigues-Diez et al.   Biomed Research International

Treatment with Anti–Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416–Induced Pulmonary Arterial Hypertension in Mice

(2013) Loredana Ciuclan et al.   AMERICAN JOURNAL OF PATHOLOGY

Enrichment map profiling of the cancer invasion front suggests regulation of colorectal cancer progression by the bone morphogenetic protein antagonist, gremlin-1

(2013) George S. Karagiannis et al.   Molecular Oncology

Gremlin-1 associates with fibrillin microfibrils in vivo and regulates mesothelioma cell survival through transcription factor slug

(2013) J A Tamminen et al.   Oncogenesis

Involvement of αvβ3 integrin in gremlin-induced angiogenesis

(2012) Cosetta Ravelli et al.   ANGIOGENESIS

Gremlin Plays a Key Role in the Pathogenesis of Pulmonary Hypertension

(2012) Edwina Cahill et al.   CIRCULATION

VEGF-Induced Vascular Permeability Is Mediated by FAK

(2012) Xiao Lei Chen et al.   DEVELOPMENTAL CELL

The bone morphogenetic protein antagonist Gremlin is overexpressed in human malignant mesothelioma

(2011) Chang-Li Wang   ONCOLOGY REPORTS

Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists

(2010) Christopher C. Rider et al.   BIOCHEMICAL JOURNAL

Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2

(2010) S. Mitola et al.   BLOOD

Bone morphogenetic protein-7 and Gremlin: New emerging therapeutic targets for diabetic nephropathy

(2009) Yanling Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension

(2008) Christine M. Costello et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Co-regulation of Gremlin and Notch signalling in diabetic nephropathy

(2007) David W. Walsh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE