Site-Specific Phosphorylation of VEGFR2 Is Mediated by Receptor Trafficking: Insights from a Computational Model

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis

(2014) M. Y. Lee et al.   DEVELOPMENT

NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

(2014) Sina Koch et al.   DEVELOPMENTAL CELL

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

(2014) M. M. Martino et al.   SCIENCE

The Pivotal Role of Vascularization in Tissue Engineering

(2013) François A. Auger et al.   Annual Review of Biomedical Engineering

Genetic Reduction of Vascular Endothelial Growth Factor Receptor 2 Rescues Aberrant Angiogenesis Caused by Epsin Deficiency

(2013) Kandice L. Tessneer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Computational model of VEGFR2 pathway to ERK activation and modulation through receptor trafficking

(2013) Wan Hua Tan et al.   CELLULAR SIGNALLING

Extracellular regulation of VEGF: Isoforms, proteolysis, and vascular patterning

(2013) Prakash Vempati et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The Neuropilin 1 Cytoplasmic Domain Is Required for VEGF-A-Dependent Arteriogenesis

(2013) Anthony Lanahan et al.   DEVELOPMENTAL CELL

Coordination of VEGF receptor trafficking and signaling by coreceptors

(2013) Masanori Nakayama et al.   EXPERIMENTAL CELL RESEARCH

Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation

(2013) Wan Hua Tan et al.   PLoS One

Neuropilin signalling in angiogenesis

(2012) Sina Koch   BIOCHEMICAL SOCIETY TRANSACTIONS

An Inside View: VEGF Receptor Trafficking and Signaling

(2012) Michael Simons   PHYSIOLOGY

Covalently grafted VEGF165 in hydrogel models upregulates the cellular pathways associated with angiogenesis

(2011) A. M. Porter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling

(2011) Helen M. Jopling et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The effect of vascular endothelial growth factor (VEGF) presentation within fibrin matrices on endothelial cell branching

(2011) Sean M. Anderson et al.   BIOMATERIALS

Binding affinities of vascular endothelial growth factor (VEGF) for heparin-derived oligosaccharides

(2011) Wenjing Zhao et al.   BIOSCIENCE REPORTS

Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output

(2011) K. Ballmer-Hofer et al.   BLOOD

Extracellular matrix in angiogenesis: dynamic structures with translational potential

(2011) Sabine A. Eming et al.   EXPERIMENTAL DERMATOLOGY

VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF

(2011) Sean M. Anderson et al.   Integrative Biology

VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation

(2011) Birger Herzog et al.   MOLECULAR BIOLOGY OF THE CELL

Rapid Phospho-Turnover by Receptor Tyrosine Kinases Impacts Downstream Signaling and Drug Binding

(2011) Laura B. Kleiman et al.   MOLECULAR CELL

Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing

(2011) M. M. Martino et al.   Science Translational Medicine

VEGF Receptor 2 Endocytic Trafficking Regulates Arterial Morphogenesis

(2010) Anthony A. Lanahan et al.   DEVELOPMENTAL CELL

Quantification and cell-to-cell variation of vascular endothelial growth factor receptors

(2010) P.I. Imoukhuede et al.   EXPERIMENTAL CELL RESEARCH

The 12th–14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain

(2010) Mikaël M. Martino et al.   FASEB JOURNAL

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

(2010) Tom T. Chen et al.   JOURNAL OF CELL BIOLOGY

Multiple mechanisms for exogenous heparin modulation of vascular endothelial growth factor activity

(2010) Errol Wijelath et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

(2010) Suphansa Sawamiphak et al.   NATURE

Quantifying the Proteolytic Release of Extracellular Matrix-Sequestered VEGF with a Computational Model

(2010) Prakash Vempati et al.   PLoS One

Systems biology of pro-angiogenic therapies targeting the VEGF system

(2010) Feilim Mac Gabhann et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Rab GTPase Regulation of VEGFR2 Trafficking and Signaling in Endothelial Cells

(2009) Helen M. Jopling et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Signal co-operation between integrins and other receptor systems

(2009) Charles H. Streuli et al.   BIOCHEMICAL JOURNAL

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

(2009) Sofie Mellberg et al.   FASEB JOURNAL

VEGFR2-PLC 1 axis is essential for endothelial specification of VEGFR2+ vascular progenitor cells

(2009) H. Sase et al.   JOURNAL OF CELL SCIENCE

Vascularization Strategies for Tissue Engineering

(2009) Michael Lovett et al.   TISSUE ENGINEERING PART B-REVIEWS

Ligand-Stimulated VEGFR2 Signaling is Regulated by Co-Ordinated Trafficking and Proteolysis

(2009) Alexander F. Bruns et al.   TRAFFIC

The role of actively released fibrin-conjugated VEGF for VEGF receptor 2 gene activation and the enhancement of angiogenesis

(2008) Martin Ehrbar et al.   BIOMATERIALS

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

(2008) H. Kawamura et al.   BLOOD

Vascular Endothelial Growth Factor (VEGF)-A165b Is a Weak In vitro Agonist for VEGF Receptor-2 Due to Lack of Coreceptor Binding and Deficient Regulation of Kinase Activity

(2008) H. Kawamura et al.   CANCER RESEARCH

Besides adhesion: new perspectives of integrin functions in angiogenesis

(2008) G. Serini et al.   CARDIOVASCULAR RESEARCH

Vascular Endothelial Growth Factor and Semaphorin Induce Neuropilin-1 Endocytosis via Separate Pathways

(2008) Anna Salikhova et al.   CIRCULATION RESEARCH

Signaling from endosomes: Location makes a difference

(2008) Lukasz Sadowski et al.   EXPERIMENTAL CELL RESEARCH

Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR

(2008) Stéphanie Cébe-Suarez et al.   FASEB JOURNAL

Neuropilin-1-VEGFR-2 Complexing Requires the PDZ-binding Domain of Neuropilin-1

(2008) Claudia Prahst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The protein tyrosine phosphatase TCPTP controls VEGFR2 signalling

(2008) E. Mattila et al.   JOURNAL OF CELL SCIENCE

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors

(2008) D. G. Nowak et al.   JOURNAL OF CELL SCIENCE

The Role of Vascular Endothelial Growth Factor in Wound Healing

(2008) Philip Bao et al.   JOURNAL OF SURGICAL RESEARCH

Regulation of scar formation by vascular endothelial growth factor

(2008) Traci A Wilgus et al.   LABORATORY INVESTIGATION

Systems Biology of Vascular Endothelial Growth Factors

(2008) Feilim Mac Gabhann et al.   MICROCIRCULATION