Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein–Gremlin signaling pathways

Slit2 ameliorates renal inflammation and fibrosis after hypoxia-and lipopolysaccharide-induced epithelial cells injury in vitro

(2017) Xiangjun Zhou et al.   EXPERIMENTAL CELL RESEARCH

Kidney Organoids: A Translational Journey

(2017) Ryuji Morizane et al.   TRENDS IN MOLECULAR MEDICINE

srGAP1 mediates the migration inhibition effect of Slit2-Robo1 in colorectal cancer

(2016) Yuyang Feng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Recombinant N-Terminal Slit2 Inhibits TGF- -Induced Fibroblast Activation and Renal Fibrosis

(2016) D. A. Yuen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Generation of functional podocytes from human induced pluripotent stem cells

(2016) Osele Ciampi et al.   Stem Cell Research

Bone Morphogenetic Proteins

(2016) Takenobu Katagiri et al.   Cold Spring Harbor Perspectives in Biology

Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling

(2016) Ismaël Morin-Poulard et al.   Nature Communications

Maximal Expression of the Evolutionarily Conserved Slit2 Gene Promoter Requires Sp1

(2015) Jacquelyn Saunders et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

ROBO2 restricts the nephrogenic field and regulates Wolffian duct–nephrogenic cord separation

(2015) Elanor N. Wainwright et al.   DEVELOPMENTAL BIOLOGY

Mutations of the SLIT2–ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract

(2015) Daw-Yang Hwang et al.   HUMAN GENETICS

Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression

(2015) Ruirui Kong et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of Slit2-Robo1 signaling promotes liver fibrosis

(2015) Jianlan Chang et al.   JOURNAL OF HEPATOLOGY

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

(2015) Ryuji Morizane et al.   NATURE BIOTECHNOLOGY

Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization

(2015) Nicolas Rama et al.   NATURE MEDICINE

BMP signalling: agony and antagony in the family

(2015) Derek P. Brazil et al.   TRENDS IN CELL BIOLOGY

Function of Slit/Robo signaling in breast cancer

(2015) Feng Gu et al.   Frontiers of Medicine

Mild Recessive Mutations in Six Fraser Syndrome-Related Genes Cause Isolated Congenital Anomalies of the Kidney and Urinary Tract

(2014) S. Kohl et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mutations in 12 known dominant disease-causing genes clarify many congenital anomalies of the kidney and urinary tract

(2014) Daw-Yang Hwang et al.   KIDNEY INTERNATIONAL

PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments

(2014) Céline Delloye-Bourgeois et al.   NATURE NEUROSCIENCE

Fibroblasts secrete Slit2 to inhibit fibrocyte differentiation and fibrosis

(2014) Darrell Pilling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serum regulation of Id1 expression by a BMP pathway and BMP responsive element

(2013) Thera C. Lewis et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells

(2013) Atsuhiro Taguchi et al.   Cell Stem Cell

Gremlin aggravates hyperglycemia-induced podocyte injury by a TGFβ/smad dependent signaling pathway

(2013) Guiying Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Rapid and Efficient Differentiation of Human Pluripotent Stem Cells into Intermediate Mesoderm That Forms Tubules Expressing Kidney Proximal Tubular Markers

(2013) A. Q. Lam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells

(2013) Yun Xia et al.   NATURE CELL BIOLOGY

Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney

(2013) M. Takasato et al.   NATURE CELL BIOLOGY

Inhibitory Effects of Robo2 on Nephrin: A Crosstalk between Positive and Negative Signals Regulating Podocyte Structure

(2012) Xueping Fan et al.   Cell Reports

Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system

(2012) Frank Costantini   Wiley Interdisciplinary Reviews-Developmental Biology

Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis

(2011) Xuguang Nie et al.   DEVELOPMENTAL BIOLOGY

Protective effect of BMP-7 against aristolochic acid-induced renal tubular epithelial cell injury

(2010) Zihua Wang et al.   TOXICOLOGY LETTERS

In VivoStructure−Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors

(2009) Jijun Hao et al.   ACS Chemical Biology

A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum

(2009) Blanca Herrera et al.   BMC CELL BIOLOGY

ROBO2 Gene Variants Are Associated with Familial Vesicoureteral Reflux

(2008) A. M. Bertoli-Avella et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development

(2008) S. Weber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Stimulatory and inhibitory signaling molecules that regulate renal branching morphogenesis

(2008) Darren Bridgewater et al.   PEDIATRIC NEPHROLOGY

Gremlin-mediated Decrease in Bone Morphogenetic Protein Signaling Promotes Pulmonary Fibrosis

(2007) Marjukka Myllärniemi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE