Ferroptosis and kidney diseases

Lipid Peroxidation Drives Renal Cyst Growth In Vitro through Activation of TMEM16A

(2019) Rainer Schreiber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

The release and activity of HMGB1 in ferroptosis

(2019) Qirong Wen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acute kidney injury overview: From basic findings to new prevention and therapy strategies

(2019) Sabrina Ribeiro Gonsalez et al.   PHARMACOLOGY & THERAPEUTICS

The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma

(2019) Wen-Hsuan Yang et al.   Cell Reports

Fumarate hydratase inactivation in hereditary leiomyomatosis and renal cell cancer is synthetic lethal with ferroptosis induction

(2018) Michael J. Kerins et al.   CANCER SCIENCE

miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma

(2018) Meiying Luo et al.   CELL DEATH AND DIFFERENTIATION

Renal tubule injury: a driving force toward chronic kidney disease

(2018) Bi-Cheng Liu et al.   KIDNEY INTERNATIONAL

Glutathione peroxidase 4 overexpression inhibits ROS-induced cell death in diffuse large B-cell lymphoma

(2018) Yuko Kinowaki et al.   LABORATORY INVESTIGATION

The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma

(2018) Heike Miess et al.   ONCOGENE

Modulating NRF2 in Disease: Timing Is Everything

(2018) Matthew Dodson et al.   Annual Review of Pharmacology and Toxicology

miR-9 regulates ferroptosis by targeting glutamic-oxaloacetic transaminase GOT1 in melanoma

(2018) Kexin Zhang et al.   MOLECULAR CARCINOGENESIS

Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy

(2018) Cong Li et al.   Frontiers in Pharmacology

Polycystic kidney disease

(2018) Carsten Bergmann et al.   Nature Reviews Disease Primers

Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression

(2017) Masahiro Nezu et al.   KIDNEY INTERNATIONAL

Chronic Kidney Disease

(2017) Angela C Webster et al.   LANCET

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

(2017) Q-z Tuo et al.   MOLECULAR PSYCHIATRY

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

(2017) Matthew J. Hangauer et al.   NATURE

CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6)

(2017) Filipa Simões et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Ferroptosis and autophagy induced cell death occur independently after siramesine and lapatinib treatment in breast cancer cells

(2017) Shumei Ma et al.   PLoS One

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Ion channels in regulated cell death

(2016) Karl Kunzelmann   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanisms of ferroptosis

(2016) Jennifer Yinuo Cao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

(2016) Diego Martin-Sanchez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Keap1 hypomorphism protects against ischemic and obstructive kidney disease

(2016) Roderick J. Tan et al.   Scientific Reports

The growth of acute kidney injury: a rising tide or just closer attention to detail?

(2015) Edward D. Siew et al.   KIDNEY INTERNATIONAL

Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation

(2015) V Forschbach et al.   Cell Death & Disease

RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction

(2014) Mark Luedde et al.   CARDIOVASCULAR RESEARCH

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

(2014) Rachid Skouta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regulated Cell Death in AKI

(2014) A. Linkermann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Pattern recognition receptors and the inflammasome in kidney disease

(2014) Jaklien C. Leemans et al.   Nature Reviews Nephrology

Synchronized renal tubular cell death involves ferroptosis

(2014) Andreas Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of regulated necrosis

(2014) Lorenzo Galluzzi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease

(2013) Dick de Zeeuw et al.   NEW ENGLAND JOURNAL OF MEDICINE

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

(2013) A. Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppressed mitochondrial biogenesis in folic acid-induced acute kidney injury and early fibrosis

(2013) L. Jay Stallons et al.   TOXICOLOGY LETTERS

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Rip1 (Receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

(2012) Andreas Linkermann et al.   KIDNEY INTERNATIONAL

Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes

(2011) Pablo E. Pergola et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic Nephropathy

(2010) T. Jiang et al.   DIABETES

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL