Modulation of Calretinin Expression in Human Mesothelioma Cells Reveals the Implication of the FAK and Wnt Signaling Pathways in Conferring Chemoresistance towards Cisplatin

Calretinin promotes invasiveness and EMT in malignant mesothelioma cells involving the activation of the FAK signaling pathway

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The Wnt regulator SFRP4 inhibits mesothelioma cell proliferation, migration, and antagonizes Wnt3a via its netrin-like domain

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FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma

(2017) Ting-Ting Cao et al.   Oncotarget

Noncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors

(2017) Jiaming Fan et al.   Oncotarget

Co-targeting of FAK and MDM2 triggers additive anti-proliferative effects in mesothelioma via a coordinated reactivation of p53

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Inhibition of disheveled-2 resensitizes cisplatin-resistant lung cancer cells through down-regulating Wnt/β-catenin signaling

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C-Jun N-terminal kinase signalling pathway in response to cisplatin

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The Genetic Landscape of Malignant Pleural Mesothelioma: Results from Massively Parallel Sequencing

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Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway

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Malignant pleural mesothelioma: an update on diagnosis and treatment options

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PKC-δ/PKC-α activity balance regulates the lethal effects of cisplatin

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Establishment of immortalized murine mesothelial cells and a novel mesothelioma cell line

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FAK signaling in human cancer as a target for therapeutics

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The emerging role of CaMKII in cancer

(2015) Yan-yang Wang et al.   Oncotarget

Mesothelioma treatment: Are we on target? A review

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Can we safely target the WNT pathway?

(2014) Michael Kahn   NATURE REVIEWS DRUG DISCOVERY

Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship

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Expression profile and function of Wnt signaling mechanisms in malignant mesothelioma cells

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A Novel Herbal Formula Induces Cell Cycle Arrest and Apoptosis in Association With Suppressing the PI3K/AKT Pathway in Human Lung Cancer A549 Cells

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Calretinin is essential for mesothelioma cell growth/survival in vitro: A potential new target for malignant mesothelioma therapy?

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A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

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FAK and WNT Signaling: The Meeting of Two Pathways in Cancer and Development

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Frizzled homolog proteins, microRNAs and Wnt signaling in cancer

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Oncogenic Wnt/β-catenin signalling pathways in the cancer-resistant epididymis have implications for cancer research

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Wnt Signaling in Skin Development, Homeostasis, and Disease

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Intratumoral Wnt2B expression affects tumor proliferation and survival in malignant pleural mesothelioma patients

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Mechanism of Cell Adaptation

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Frizzled7 as an emerging target for cancer therapy

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Wnt5a as a Predictor in Poor Clinical Outcome of Patients and a Mediator in Chemoresistance of Ovarian Cancer

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Malignant mesothelioma: Facts, Myths, and Hypotheses

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PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

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Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling

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SV40-Induced Expression of Calretinin Protects Mesothelial Cells from Asbestos Cytotoxicity and May Be a Key Factor Contributing to Mesothelioma Pathogenesis

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c-Jun N-terminal kinase (JNK) signaling: Recent advances and challenges

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Dishevelled: The hub of Wnt signaling

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Discovery and Characterization of a Small Molecule Inhibitor of the PDZ Domain of Dishevelled

(2009) David Grandy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/β-catenin pathway

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Malignant Mesothelioma—A Connective Tissue Tumor with Proteoglycan-Dependent Differentiation

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Analyzing real-time PCR data by the comparative CT method

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