Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway
Authors
Keywords
-
Journal
Stem Cells International
Volume 2016, Issue -, Pages 1-16
Publisher
Hindawi Limited
Online
2016-11-09
DOI
10.1155/2016/1690896
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- TMPRSS4 induces cancer stem cell-like properties in lung cancer cells and correlates with ALDH expression in NSCLC patients
- (2016) Arrate L. de Aberasturi et al. CANCER LETTERS
- An oncogenic role of miR-592 in tumorigenesis of human colorectal cancer by targeting Forkhead Box O3A (FoxO3A)
- (2016) Qi Fu et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Aldehyde dehydrogenase 1A1 in stem cells and cancer
- (2016) Hiroyuki Tomita et al. Oncotarget
- Wnt/β-Catenin signaling reduces Bacillus Calmette-Guerin-induced macrophage necrosis through a ROS -mediated PARP/AIF-dependent pathway
- (2015) Xiaoling Wu et al. BMC IMMUNOLOGY
- Cancer statistics, 2015
- (2015) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Non-canonical WNT signalling in the lung
- (2015) Changgong Li et al. JOURNAL OF BIOCHEMISTRY
- Inhibition of β-Catenin Enhances the Anticancer Effect of Irreversible EGFR-TKI in EGFR-Mutated Non–small-cell Lung Cancer with a T790M Mutation
- (2015) Yosuke Togashi et al. Journal of Thoracic Oncology
- Wnt signaling regulates the stemness of lung cancer stem cells and its inhibitors exert anticancer effect on lung cancer SPC-A1 cells
- (2015) Xueyan Zhang et al. MEDICAL ONCOLOGY
- Upregulation of the expression of Wnt5a promotes the proliferation of pancreatic cancer cells in vitro and in a nude mouse model
- (2015) HAIJI BO et al. Molecular Medicine Reports
- Targeting Notch, Hedgehog and Wnt pathways in cancer stem cells: clinical update
- (2015) Naoko Takebe et al. Nature Reviews Clinical Oncology
- Ror2 as a Therapeutic Target in Cancer
- (2015) Zufan Debebe et al. PHARMACOLOGY & THERAPEUTICS
- WNT5A promotes stemness characteristics in nasopharyngeal carcinoma cells leading to metastasis and tumorigenesis
- (2015) Li Qin et al. Oncotarget
- Over-expression of ROR2 and Wnt5a cooperatively correlates with unfavorable prognosis in patients with non-small cell lung cancer
- (2015) Chenlin Lu et al. Oncotarget
- Critical role of Wnt/β-catenin signaling in driving epithelial ovarian cancer platinum resistance
- (2015) Anil Belur Nagaraj et al. Oncotarget
- Elevated β-catenin pathway as a novel target for patients with resistance to EGF receptor targeting drugs
- (2015) Asuka Nakata et al. Scientific Reports
- Emerging Roles of MicroRNAs in EGFR-Targeted Therapies for Lung Cancer
- (2015) Fei Han et al. Biomed Research International
- Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway
- (2015) Tsai-Hsien Hung et al. Oncotarget
- Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDHhighCD44+ phenotype and sphere-forming capacity
- (2014) Lourdes Cortes-Dericks et al. BMC CANCER
- A Noncanonical Frizzled2 Pathway Regulates Epithelial-Mesenchymal Transition and Metastasis
- (2014) Taranjit S. Gujral et al. CELL
- Essential Role of Aldehyde Dehydrogenase 1A3 for the Maintenance of Non-Small Cell Lung Cancer Stem Cells Is Associated with the STAT3 Pathway
- (2014) C. Shao et al. CLINICAL CANCER RESEARCH
- WNT5A modulates cell cycle progression and contributes to the chemoresistance in pancreatic cancer cells
- (2014) Wei Wei et al. Hepatobiliary & Pancreatic Diseases International
- Expression of the novel Wnt receptor ROR2 is increased in breast cancer and may regulate both β-catenin dependent and independent Wnt signalling
- (2014) C. Henry et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors
- (2014) Jamie N. Anastas et al. JOURNAL OF CLINICAL INVESTIGATION
- Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression
- (2014) Zdenka Prgomet et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- A Wnt/β-catenin negative feedback loop represses TLR-triggered inflammatory responses in alveolar epithelial cells
- (2014) Yong Li et al. MOLECULAR IMMUNOLOGY
- Wnt5a promotes vasculogenic mimicry and epithelial-mesenchymal transition via protein kinase Cα in epithelial ovarian cancer
- (2014) HONG QI et al. ONCOLOGY REPORTS
- Wnt signaling pathway pharmacogenetics in non-small cell lung cancer
- (2014) D J Stewart et al. PHARMACOGENOMICS JOURNAL
- Overexpression of RNF146 in Non-Small Cell Lung Cancer Enhances Proliferation and Invasion of Tumors through the Wnt/β-catenin Signaling Pathway
- (2014) Ying Gao et al. PLoS One
- ALDH Maintains the Stemness of Lung Adenoma Stem Cells by Suppressing the Notch/CDK2/CCNE Pathway
- (2014) Zhongjun Li et al. PLoS One
- Challenging role of Wnt5a and its signaling pathway in cancer metastasis (Review)
- (2014) NENG ZHU et al. Experimental and Therapeutic Medicine
- Overexpression of Wnt5a Promotes Angiogenesis in NSCLC
- (2014) Lingli Yao et al. Biomed Research International
- Inhibition of cytoplasmic GSK-3β increases cisplatin resistance through activation of Wnt/β-catenin signaling in A549/DDP cells
- (2013) Yuan Gao et al. CANCER LETTERS
- Anti-HDGF Targets Cancer and Cancer Stromal Stem Cells Resistant to Chemotherapy
- (2013) J. Zhao et al. CLINICAL CANCER RESEARCH
- Wnt Signaling Pathway in Non-Small Cell Lung Cancer
- (2013) D. J. Stewart JNCI-Journal of the National Cancer Institute
- A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing
- (2013) Maria Carolina Florian et al. NATURE
- Down-Regulation of Canonical and Up-Regulation of Non-Canonical Wnt Signalling in the Carcinogenic Process of Squamous Cell Lung Carcinoma
- (2013) Domokos Bartis et al. PLoS One
- Wnt5a Is Associated with Cigarette Smoke-Related Lung Carcinogenesis via Protein Kinase C
- (2013) Young Mi Whang et al. PLoS One
- The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis
- (2012) Caroline E. Ford et al. INTERNATIONAL JOURNAL OF CANCER
- Wnt Signaling in Skin Development, Homeostasis, and Disease
- (2012) X. Lim et al. Cold Spring Harbor Perspectives in Biology
- Wnt/Ca2+ signaling pathway: a brief overview
- (2011) Antara De ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Wnt5a: its signalling, functions and implication in diseases
- (2011) A. Kikuchi et al. Acta Physiologica
- Frizzled-8 as a putative therapeutic target in human lung cancer
- (2011) Hua-qing Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Wnt5a as a Predictor in Poor Clinical Outcome of Patients and a Mediator in Chemoresistance of Ovarian Cancer
- (2011) Chunjie Peng et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- The Wnt5a/Ror2 noncanonical signaling pathway inhibits canonical Wnt signaling in K562 cells
- (2010) Wei Si INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- EMX2 is epigenetically silenced and suppresses growth in human lung cancer
- (2010) J Okamoto et al. ONCOGENE
- WNT5A Is a Regulator of Fibroblast Proliferation and Resistance to Apoptosis
- (2009) Louis J. Vuga et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The opposing roles of Wnt-5a in cancer
- (2009) S L McDonald et al. BRITISH JOURNAL OF CANCER
- Wnt signalling and cancer stem cells
- (2009) Jesús Espada et al. Clinical & Translational Oncology
- Transcriptional mechanisms of WNT5A based on NF-κB, Hedgehog, TGFβ, and Notch signaling cascades
- (2009) Katoh INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma
- (2009) M P O’Connell et al. ONCOGENE
- Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma
- (2009) G Akiri et al. ONCOGENE
- Tumor formation due to abnormalities in the β-catenin-independent pathway of Wnt signaling
- (2008) Akira Kikuchi et al. CANCER SCIENCE
- WNT5A Exhibits Tumor-Suppressive Activity through Antagonizing the Wnt/ -Catenin Signaling, and Is Frequently Methylated in Colorectal Cancer
- (2008) J. Ying et al. CLINICAL CANCER RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started