C-Jun N-terminal kinase signalling pathway in response to cisplatin

Translational regulation of the mRNA encoding the ubiquitin peptidase USP1 involved in the DNA damage response as a determinant of Cisplatin resistance

(2016) Tony Sourisseau et al.   CELL CYCLE

Cisplatin resistance in human cervical, ovarian and lung cancer cells

(2015) Jianli Chen et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents

(2015) I. A. Vasilevskaya et al.   CLINICAL CANCER RESEARCH

JNK signaling is converted from anti- to pro-tumor pathway by Ras-mediated switch of Warts activity

(2015) Masato Enomoto et al.   DEVELOPMENTAL BIOLOGY

Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy

(2015) Helen HW Chen et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling

(2015) Zongyuan Yang et al.   FEBS Journal

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition

(2015) Qiong Wang et al.   Oncotarget

C-Jun N-terminal kinase (JNK) isoforms play differing roles in otitis media

(2014) William Yao et al.   BMC IMMUNOLOGY

Cancer Cell Dormancy in Novel Mouse Models for Reversible Pancreatic Cancer: A Lingering Challenge in the Development of Targeted Therapies

(2014) Wan-Chi Lin et al.   CANCER RESEARCH

ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis

(2014) Y Shi et al.   CELL DEATH AND DIFFERENTIATION

Differential roles of ATF-2 in survival and DNA repair contributing to radioresistance induced by autocrine soluble factors in A549 lung cancer cells

(2014) Sejal Desai et al.   CELLULAR SIGNALLING

Recent Progress in the Design, Study, and Development of c-Jun N-Terminal Kinase Inhibitors as Anticancer Agents

(2014) Abdellah Messoussi et al.   CHEMISTRY & BIOLOGY

Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP

(2014) L Chen et al.   Cell Death & Disease

Bcl-2 Family Proteins Are Involved in the Signal Crosstalk between Endoplasmic Reticulum Stress and Mitochondrial Dysfunction in Tumor Chemotherapy Resistance

(2014) Jing Su et al.   Biomed Research International

Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer

(2013) Parthasarathy Seshacharyulu et al.   CANCER LETTERS

Cisplatin Resistance Associated with PARP Hyperactivation

(2013) J. Michels et al.   CANCER RESEARCH

The PDGFRβ–AKT Pathway Contributes to CDDP-Acquired Resistance in Testicular Germ Cell Tumors

(2013) M. Juliachs et al.   CLINICAL CANCER RESEARCH

Oppositional Regulation of Noxa by JNK1 and JNK2 during Apoptosis Induced by Proteasomal Inhibitors

(2013) Sabine Pietkiewicz et al.   PLoS One

JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells

(2012) Zhiwei Zhao et al.   BIOCHEMICAL JOURNAL

Tissue Platinum Concentration and Tumor Response in Non–Small-Cell Lung Cancer

(2012) Eric S. Kim et al.   JOURNAL OF CLINICAL ONCOLOGY

DNA-PKcs-mediated stabilization of p53 by JNK2 is involved in arsenite-induced DNA damage and apoptosis in human embryo lung fibroblast cells

(2012) Yuan Li et al.   TOXICOLOGY LETTERS

Growth Control: Myc and Yorkie Get Connected

(2011) Hugo Stocker   CURRENT BIOLOGY

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

Evidence for a Growth-Stabilizing Regulatory Feedback Mechanism between Myc and Yorkie, the Drosophila Homolog of Yap

(2010) Ricardo M. Neto-Silva et al.   DEVELOPMENTAL CELL

Involvement of JNK in the regulation of autophagic cell death

(2010) S Shimizu et al.   ONCOGENE

Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding

(2010) Y. Diao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

dMyc Functions Downstream of Yorkie to Promote the Supercompetitive Behavior of Hippo Pathway Mutant Cells

(2010) Marcello Ziosi et al.   PLoS Genetics

c-Jun N-terminal kinase (JNK) signaling: Recent advances and challenges

(2009) Marie A. Bogoyevitch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The TAK1-JNK cascade is required for IRF3 function in the innate immune response

(2009) Bianhong Zhang et al.   CELL RESEARCH

Endoplasmic Reticulum Stress-Mediated Autophagy/Apoptosis Induced by Capsaicin (8-Methyl-N-vanillyl-6-nonenamide) and Dihydrocapsaicin is Regulated by the Extent of c-Jun NH2-Terminal Kinase/Extracellular Signal-Regulated Kinase Activation in WI38 Lung Epithelial Fibroblast Cells

(2009) S.-H. Oh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

JNK mediates UVB-induced apoptosis upstream lysosomal membrane permeabilization and Bcl-2 family proteins

(2008) Cecilia Bivik et al.   APOPTOSIS

Platinum compounds 30 years after the introduction of cisplatin: Implications for the treatment of ovarian cancer

(2008) Franco Muggia   GYNECOLOGIC ONCOLOGY

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells

(2008) D-D Li et al.   ONCOGENE