FK506 binding protein 51 integrates pathways of adaptation

Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation

(2016) Rachel Yehuda et al.   BIOLOGICAL PSYCHIATRY

HSF1: Guardian of Proteostasis in Cancer

(2016) Chengkai Dai et al.   TRENDS IN CELL BIOLOGY

Signaling via the NFκB system

(2016) Simon Mitchell et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

FKBP5/FKBP51 enhances autophagy to synergize with antidepressant action

(2015) Nils C Gassen et al.   Autophagy

Molecular mechanisms of repeated social defeat-induced glucocorticoid resistance: Role of microRNA

(2015) Seung Ho Jung et al.   BRAIN BEHAVIOR AND IMMUNITY

Biological relevance of Hsp90-binding immunophilins in cancer development and treatment

(2015) Gisela I. Mazaira et al.   INTERNATIONAL JOURNAL OF CANCER

Prolyl Isomerization and Its Catalysis in Protein Folding and Protein Function

(2015) Philipp A.M. Schmidpeter et al.   JOURNAL OF MOLECULAR BIOLOGY

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties

(2015) J. Hartmann et al.   JOURNAL OF NEUROSCIENCE

FKBP51 inhibits GSK3β and augments the effects of distinct psychotropic medications

(2015) N C Gassen et al.   MOLECULAR PSYCHIATRY

Autophagy and autophagy-related proteins in the immune system

(2015) Shusaku T Shibutani et al.   NATURE IMMUNOLOGY

Association between FKBP5 Functional Polymorphisms and Completed Suicide

(2015) Sylwia Fudalej et al.   NEUROPSYCHOBIOLOGY

FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma

(2015) Simona Romano et al.   NUCLEIC ACIDS RESEARCH

Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress

(2015) Ali B. Rodgers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine

(2015) Nils C. Gassen et al.   Science Signaling

Catalytic subunits of the phosphatase calcineurin interact with NF-κB-inducing kinase (NIK) and attenuate NIK-dependent gene expression

(2015) Miho Shinzawa et al.   Scientific Reports

Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine

(2015) Nils C. Gassen et al.   Science Signaling

The FKBP51-Glucocorticoid Receptor Balance in Stress-Related Mental Disorders

(2015) Gabriel R. Fries et al.   Current Molecular Pharmacology

The epigenetic side of human adaptation: hypotheses, evidences and theories

(2014) Cristina Giuliani et al.   ANNALS OF HUMAN BIOLOGY

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways

(2014) Mikko Taipale et al.   CELL

NF-κB Transcriptional Activity Is Modulated by FK506-binding Proteins FKBP51 and FKBP52

(2014) Alejandra G. Erlejman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interplay between diet-induced obesity and chronic stress in mice: potential role of FKBP51

(2014) Georgia Balsevich et al.   JOURNAL OF ENDOCRINOLOGY

FKBP51 Reciprocally Regulates GRα and PPARγ Activation via the Akt-p38 Pathway

(2014) Lance A. Stechschulte et al.   MOLECULAR ENDOCRINOLOGY

Selective inhibitors of the FK506-binding protein 51 by induced fit

(2014) Steffen Gaali et al.   Nature Chemical Biology

FKBP5 variation is associated with the acute and chronic effects of nicotine

(2014) K P Jensen et al.   PHARMACOGENOMICS JOURNAL

Mitochondria–Nucleus Shuttling FK506-Binding Protein 51 Interacts with TRAF Proteins and Facilitates the RIG-I-Like Receptor-Mediated Expression of Type I IFN

(2014) Taishin Akiyama et al.   PLoS One

Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency

(2014) Jonathan J. Sabbagh et al.   PLoS One

Effect of the common functional FKBP5 variant (rs1360780) on the hypothalamic-pituitary-adrenal axis and peripheral blood gene expression

(2014) Takashi Fujii et al.   PSYCHONEUROENDOCRINOLOGY

Stress-related genes and heroin addiction: A role for a functional FKBP5 haplotype

(2014) O. Levran et al.   PSYCHONEUROENDOCRINOLOGY

Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans

(2014) Nils C. Gassen et al.   PLOS MEDICINE

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

MicroRNA-100/99a, deregulated in acute lymphoblastic leukaemia, suppress proliferation and promote apoptosis by regulating the FKBP51 and IGF1R/mTOR signalling pathways

(2013) X-J Li et al.   BRITISH JOURNAL OF CANCER

Paternal Stress Exposure Alters Sperm MicroRNA Content and Reprograms Offspring HPA Stress Axis Regulation

(2013) A. B. Rodgers et al.   JOURNAL OF NEUROSCIENCE

DNA methylation dynamics in health and disease

(2013) Yehudit Bergman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

FKBP5 genetic variation

(2013) Katarzyna A. Ellsworth et al.   Pharmacogenetics and Genomics

Cryptic Variation in Morphological Evolution: HSP90 as a Capacitor for Loss of Eyes in Cavefish

(2013) N. Rohner et al.   SCIENCE

Epigenetic Risk Factors in PTSD and Depression

(2013) Florian Joachim Raabe et al.   Frontiers in Psychiatry

Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes

(2012) Linda Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

NFAT control of innate immunity

(2012) J. Fric et al.   BLOOD

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

NF-κB Signaling Pathways

(2012) Stefka Mincheva-Tasheva et al.   NEUROSCIENTIST

Interaction ofFKBP5Gene Variants and Adverse Life Events in Predicting Depression Onset: Results From a 10-Year Prospective Community Study

(2011) Petra Zimmermann et al.   AMERICAN JOURNAL OF PSYCHIATRY

Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

(2011) Julius Anckar et al.   Annual Review of Biochemistry

FK506 Binding Protein 5 Shapes Stress Responsiveness: Modulation of Neuroendocrine Reactivity and Coping Behavior

(2011) Chadi Touma et al.   BIOLOGICAL PSYCHIATRY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

FKBP51 and the NF-κB regulatory pathway in cancer

(2011) Simona Romano et al.   CURRENT OPINION IN PHARMACOLOGY

Neuropsin cleaves EphB2 in the amygdala to control anxiety

(2011) Benjamin K. Attwood et al.   NATURE

The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress

(2011) Jakob Hartmann et al.   NEUROPHARMACOLOGY

Moderation of Adult Depression by a Polymorphism in the FKBP5 Gene and Childhood Physical Abuse in the General Population

(2011) Katja Appel et al.   NEUROPSYCHOPHARMACOLOGY

A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51

(2011) John C. O'Leary et al.   PLoS One

FKBP51 and FKBP52 in signaling and disease

(2011) Cheryl L. Storer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Chronic Corticosterone Exposure Increases Expression and Decreases Deoxyribonucleic Acid Methylation ofFkbp5in Mice

(2010) Richard S. Lee et al.   ENDOCRINOLOGY

Glucocorticoids, prenatal stress and the programming of disease

(2010) Anjanette Harris et al.   HORMONES AND BEHAVIOR

Glucocorticoid Receptor Activates PoisedFKBP51Locus through Long-Distance Interactions

(2010) Ville Paakinaho et al.   MOLECULAR ENDOCRINOLOGY

Cellular strategies for controlling protein aggregation

(2010) Jens Tyedmers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differential Impact of Tetratricopeptide Repeat Proteins on the Steroid Hormone Receptors

(2010) Jan-Philip Schülke et al.   PLoS One

Hsp90 and Environmental Stress Transform the Adaptive Value of Natural Genetic Variation

(2010) D. F. Jarosz et al.   SCIENCE

Modulation of glucocorticoid receptor nuclear translocation in neurons by immunophilins FKBP51 and FKBP52: Implications for major depressive disorder

(2009) Erick T. Tatro et al.   BRAIN RESEARCH

FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt

(2009) Huadong Pei et al.   CANCER CELL

Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells

(2009) S Romano et al.   CELL DEATH AND DIFFERENTIATION

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

(2009) E Laane et al.   CELL DEATH AND DIFFERENTIATION

Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls

(2008) Marcus Ising et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Association of FKBP5 Polymorphisms and Childhood Abuse With Risk of Posttraumatic Stress Disorder Symptoms in Adults

(2008) Elisabeth B. Binder   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Family-based association of FKBP5 in bipolar disorder

(2008) V L Willour et al.   MOLECULAR PSYCHIATRY

FKBP Family Proteins: Immunophilins with Versatile Biological Functions

(2008) Cong Bao Kang et al.   NEUROSIGNALS