- Home
- Publications
- Publication Search
- Publication Details
Title
Drug Development of Therapeutic Monoclonal Antibodies
Authors
Keywords
Respiratory Syncytial Virus, Adalimumab, Progressive Multifocal Leukoencephalopathy, Ranibizumab, Alemtuzumab
Journal
BIODRUGS
Volume 30, Issue 4, Pages 275-293
Publisher
Springer Nature
Online
2016-06-26
DOI
10.1007/s40259-016-0181-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Management of adverse events in the treatment of patients with immunoglobulin therapy: A review of evidence
- (2016) Patrick Cherin et al. AUTOIMMUNITY REVIEWS
- Influence of tumour burden on trastuzumab pharmacokinetics in HER2 positive non-metastatic breast cancer
- (2016) Guillemette Bernadou et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Pharmacokinetics and Safety of Elotuzumab Combined With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma and Various Levels of Renal Impairment: Results of a Phase Ib Study
- (2016) Jesus Berdeja et al. Clinical Lymphoma Myeloma & Leukemia
- A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins
- (2015) Katherine L. Gill et al. AAPS Journal
- Population pharmacokinetics-pharmacodynamics of vedolizumab in patients with ulcerative colitis and Crohn's disease
- (2015) M. Rosario et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Why therapeutic drug monitoring is needed for monoclonal antibodies and how do we implement this?
- (2015) DR Mould CLINICAL PHARMACOLOGY & THERAPEUTICS
- Mathematical modeling of receptor occupancy data: A valuable technology for biotherapeutic drug development
- (2015) Mary E. Spilker et al. CYTOMETRY PART B-CLINICAL CYTOMETRY
- The Pharmacokinetics of Biologics: A Primer
- (2015) Diane R. Mould DIGESTIVE DISEASES
- Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative Colitis
- (2015) Johannan F. Brandse et al. GASTROENTEROLOGY
- Clinical Development Strategies and Outcomes in First-in-Human Trials of Monoclonal Antibodies
- (2015) Diego Tosi et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical pharmacology of bispecific antibody constructs
- (2015) Chetan Rathi et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Challenges and considerations for development of therapeutic proteins in pediatric patients
- (2015) Yi Zhang et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Pharmacokinetic and pharmacodynamic interactions between palifermin and heparin
- (2015) Bing-Bing Yang et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Dashboard systems: Pharmacokinetic/pharmacodynamic mediated dose optimization for monoclonal antibodies
- (2015) Diane R. Mould et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Progressive multifocal leukoencephalopathy: current treatment options and future perspectives
- (2015) Dejan Pavlovic et al. Therapeutic Advances in Neurological Disorders
- Population pharmacokinetics and exposure–response analyses of trastuzumab in patients with advanced gastric or gastroesophageal junction cancer
- (2014) Valérie F. Cosson et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Population Pharmacokinetics of Daclizumab High-Yield Process in Healthy Volunteers: Integrated Analysis of Intravenous and Subcutaneous, Single- and Multiple-Dose Administration
- (2014) Ahmed A. Othman et al. CLINICAL PHARMACOKINETICS
- Pharmacokinetics and Pharmacokinetic–Pharmacodynamic Relationships of Monoclonal Antibodies in Children
- (2014) Helena Edlund et al. CLINICAL PHARMACOKINETICS
- Alemtuzumab: A Review of Its Use in Patients with Relapsing Multiple Sclerosis
- (2014) Karly P. Garnock-Jones DRUGS
- Pharmacokinetics of Ranibizumab after Intravitreal Administration in Patients with Retinal Vein Occlusion or Diabetic Macular Edema
- (2014) Yi Zhang et al. OPHTHALMOLOGY
- Fit-for purpose use of mouse models to improve predictivity of cancer therapeutics evaluation
- (2014) K. Wartha et al. PHARMACOLOGY & THERAPEUTICS
- Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein
- (2014) John T. Bates et al. VIROLOGY
- Giving monoclonal antibodies to healthy volunteers in phase 1 trials: is it safe?
- (2013) Elizabeth Tranter et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Pharmacokinetics of panitumumab in a patient with liver dysfunction: a case report
- (2013) L. L. Krens et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Human regulatory T cells are selectively activated by low-dose application of the CD28 superagonist TGN1412/TAB08
- (2013) Paula Tabares et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Population Pharmacokinetics of Belimumab Following Intravenous Administration in Patients With Systemic Lupus Erythematosus
- (2013) Herbert Struemper et al. JOURNAL OF CLINICAL PHARMACOLOGY
- The Antibody Drug Absorption Following Subcutaneous or Intramuscular Administration and Its Mathematical Description by Coupling Physiologically Based Absorption Process with the Conventional Compartment Pharmacokinetic Model
- (2013) Liang Zhao et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Contribution of Renal and Non-Renal Clearance on Increased Total Clearance of Adalimumab in Glomerular Disease
- (2013) Brittney V. Roberts et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Outcomes Following Infliximab Therapy for Pediatric Patients Hospitalized With Refractory Colitis–Predominant IBD
- (2013) Tolulope O. Falaiye et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Modeling pharmacokinetics/pharmacodynamics of abatacept and disease progression in collagen-induced arthritic rats: a population approach
- (2013) Hoi-Kei Lon et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy
- (2012) Narendra Chirmule et al. AAPS Journal
- Biacore surface matrix effects on the binding kinetics and affinity of an antigen/antibody complex
- (2012) Andrew W. Drake et al. ANALYTICAL BIOCHEMISTRY
- Physiologically Based Pharmacokinetic (PBPK) Modeling in Children
- (2012) J S Barrett et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Anti-TNF Monoclonal Antibodies in Inflammatory Bowel Disease: Pharmacokinetics-Based Dosing Paradigms
- (2012) I Ordás et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Cytochrome P450 variations in different ethnic populations
- (2012) Joseph McGraw et al. Expert Opinion on Drug Metabolism & Toxicology
- Increasing Serum Half-life and Extending Cholesterol Loweringin Vivoby Engineering Antibody with pH-sensitive Binding to PCSK9
- (2012) Javier Chaparro-Riggers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterizing the Impact of Renal Impairment on the Clinical Pharmacology of Biologics
- (2012) Bernd Meibohm et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Rational development and utilization of antibody-based therapeutic proteins in pediatrics
- (2012) Zhenhua Xu et al. PHARMACOLOGY & THERAPEUTICS
- Quantitative Prediction of Human Pharmacokinetics for Monoclonal Antibodies
- (2011) Jennifer Q. Dong et al. CLINICAL PHARMACOKINETICS
- Disease–Drug–Drug Interaction Involving Tocilizumab and Simvastatin in Patients With Rheumatoid Arthritis
- (2011) C Schmitt et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Pharmacokinetic Properties of Infliximab in Children and Adults with Crohn's Disease: A Retrospective Analysis of Data from 2 Phase III Clinical Trials
- (2011) Adedigbo A. Fasanmade et al. CLINICAL THERAPEUTICS
- Serum albumin concentration: a predictive factor of infliximab pharmacokinetics and clinical response in patients with ulcerative colitis
- (2011) A.A. Fasanmade et al. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
- Projecting human pharmacokinetics of therapeutic antibodies from nonclinical data
- (2011) Rong Deng et al. mAbs
- Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
- (2011) Peter Carmeliet et al. NATURE REVIEWS DRUG DISCOVERY
- Pharmacokinetic-Pharmacodynamic Disease Progression Model for Effect of Etanercept in Lewis Rats with Collagen-Induced Arthritis
- (2011) Hoi-Kei Lon et al. PHARMACEUTICAL RESEARCH
- Prediction of Exposure–Response Relationships to Support First-in-Human Study Design
- (2010) John P. Gibbs AAPS Journal
- Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies
- (2010) Diane R. Mould et al. BIODRUGS
- Population Pharmacokinetics of Therapeutic Monoclonal Antibodies
- (2010) Nathanael L. Dirks et al. CLINICAL PHARMACOKINETICS
- Preclinical development of monoclonal antibodies
- (2010) Kathryn Chapman et al. mAbs
- Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies
- (2010) Frank R. Brennan et al. mAbs
- Anti-infliximab and anti-adalimumab antibodies in relation to response to adalimumab in infliximab switchers and anti-tumour necrosis factor naive patients: a cohort study
- (2009) G. M. Bartelds et al. ANNALS OF THE RHEUMATIC DISEASES
- On Setting the First Dose in Man: Quantitating Biotherapeutic Drug-Target Binding through Pharmacokinetic and Pharmacodynamic Models
- (2009) Philip J. Lowe et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- The minimum anticipated biological effect level (MABEL) for selection of first human dose in clinical trials with monoclonal antibodies
- (2009) Patrick Y Muller et al. CURRENT OPINION IN BIOTECHNOLOGY
- Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis
- (2009) Adedigbo A. Fasanmade et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Fixed Dosing Versus Body Size-Based Dosing of Monoclonal Antibodies in Adult Clinical Trials
- (2009) Diane D. Wang et al. JOURNAL OF CLINICAL PHARMACOLOGY
- The In Silico Child: Using Simulation to Guide Pediatric Drug Development and Manage Pediatric Pharmacotherapy
- (2009) Stephanie Läer et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Concepts and Challenges in Quantitative Pharmacology and Model-Based Drug Development
- (2008) Liping Zhang et al. AAPS Journal
- Tumor burden influences exposure and response to rituximab: pharmacokinetic-pharmacodynamic modeling using a syngeneic bioluminescent murine model expressing human CD20
- (2008) D. Dayde et al. BLOOD
- Clinical pharmacokinetics of bevacizumab in patients with solid tumors
- (2008) Jian-Feng Lu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Engineered Antibodies of IgG1/IgG3 Mixed Isotype with Enhanced Cytotoxic Activities
- (2008) A. Natsume et al. CANCER RESEARCH
- Trastuzumab cardiotoxicity: biological hypotheses and clinical open issues
- (2008) Emilio Bria et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Population Pharmacokinetics of Cetuximab in Patients With Squamous Cell Carcinoma of the Head and Neck
- (2008) Nathanae L. Dirks et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Population Pharmacokinetics of Infliximab in Patients With Ankylosing Spondylitis
- (2008) Zhenhua Xu et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Quantitative Dynamic Models of Arthritis Progression in the Rat
- (2008) Justin C. Earp et al. PHARMACEUTICAL RESEARCH
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started