标题
Drug Development of Therapeutic Monoclonal Antibodies
作者
关键词
Respiratory Syncytial Virus, Adalimumab, Progressive Multifocal Leukoencephalopathy, Ranibizumab, Alemtuzumab
出版物
BIODRUGS
Volume 30, Issue 4, Pages 275-293
出版商
Springer Nature
发表日期
2016-06-26
DOI
10.1007/s40259-016-0181-6
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Management of adverse events in the treatment of patients with immunoglobulin therapy: A review of evidence
- (2016) Patrick Cherin et al. AUTOIMMUNITY REVIEWS
- Influence of tumour burden on trastuzumab pharmacokinetics in HER2 positive non-metastatic breast cancer
- (2016) Guillemette Bernadou et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Pharmacokinetics and Safety of Elotuzumab Combined With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma and Various Levels of Renal Impairment: Results of a Phase Ib Study
- (2016) Jesus Berdeja et al. Clinical Lymphoma Myeloma & Leukemia
- A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins
- (2015) Katherine L. Gill et al. AAPS Journal
- Population pharmacokinetics-pharmacodynamics of vedolizumab in patients with ulcerative colitis and Crohn's disease
- (2015) M. Rosario et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Why therapeutic drug monitoring is needed for monoclonal antibodies and how do we implement this?
- (2015) DR Mould CLINICAL PHARMACOLOGY & THERAPEUTICS
- Mathematical modeling of receptor occupancy data: A valuable technology for biotherapeutic drug development
- (2015) Mary E. Spilker et al. CYTOMETRY PART B-CLINICAL CYTOMETRY
- The Pharmacokinetics of Biologics: A Primer
- (2015) Diane R. Mould DIGESTIVE DISEASES
- Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative Colitis
- (2015) Johannan F. Brandse et al. GASTROENTEROLOGY
- Clinical Development Strategies and Outcomes in First-in-Human Trials of Monoclonal Antibodies
- (2015) Diego Tosi et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical pharmacology of bispecific antibody constructs
- (2015) Chetan Rathi et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Challenges and considerations for development of therapeutic proteins in pediatric patients
- (2015) Yi Zhang et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Pharmacokinetic and pharmacodynamic interactions between palifermin and heparin
- (2015) Bing-Bing Yang et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Dashboard systems: Pharmacokinetic/pharmacodynamic mediated dose optimization for monoclonal antibodies
- (2015) Diane R. Mould et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Progressive multifocal leukoencephalopathy: current treatment options and future perspectives
- (2015) Dejan Pavlovic et al. Therapeutic Advances in Neurological Disorders
- Population pharmacokinetics and exposure–response analyses of trastuzumab in patients with advanced gastric or gastroesophageal junction cancer
- (2014) Valérie F. Cosson et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Population Pharmacokinetics of Daclizumab High-Yield Process in Healthy Volunteers: Integrated Analysis of Intravenous and Subcutaneous, Single- and Multiple-Dose Administration
- (2014) Ahmed A. Othman et al. CLINICAL PHARMACOKINETICS
- Pharmacokinetics and Pharmacokinetic–Pharmacodynamic Relationships of Monoclonal Antibodies in Children
- (2014) Helena Edlund et al. CLINICAL PHARMACOKINETICS
- Alemtuzumab: A Review of Its Use in Patients with Relapsing Multiple Sclerosis
- (2014) Karly P. Garnock-Jones DRUGS
- Pharmacokinetics of Ranibizumab after Intravitreal Administration in Patients with Retinal Vein Occlusion or Diabetic Macular Edema
- (2014) Yi Zhang et al. OPHTHALMOLOGY
- Fit-for purpose use of mouse models to improve predictivity of cancer therapeutics evaluation
- (2014) K. Wartha et al. PHARMACOLOGY & THERAPEUTICS
- Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein
- (2014) John T. Bates et al. VIROLOGY
- Giving monoclonal antibodies to healthy volunteers in phase 1 trials: is it safe?
- (2013) Elizabeth Tranter et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Pharmacokinetics of panitumumab in a patient with liver dysfunction: a case report
- (2013) L. L. Krens et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Human regulatory T cells are selectively activated by low-dose application of the CD28 superagonist TGN1412/TAB08
- (2013) Paula Tabares et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Population Pharmacokinetics of Belimumab Following Intravenous Administration in Patients With Systemic Lupus Erythematosus
- (2013) Herbert Struemper et al. JOURNAL OF CLINICAL PHARMACOLOGY
- The Antibody Drug Absorption Following Subcutaneous or Intramuscular Administration and Its Mathematical Description by Coupling Physiologically Based Absorption Process with the Conventional Compartment Pharmacokinetic Model
- (2013) Liang Zhao et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Contribution of Renal and Non-Renal Clearance on Increased Total Clearance of Adalimumab in Glomerular Disease
- (2013) Brittney V. Roberts et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Outcomes Following Infliximab Therapy for Pediatric Patients Hospitalized With Refractory Colitis–Predominant IBD
- (2013) Tolulope O. Falaiye et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Modeling pharmacokinetics/pharmacodynamics of abatacept and disease progression in collagen-induced arthritic rats: a population approach
- (2013) Hoi-Kei Lon et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy
- (2012) Narendra Chirmule et al. AAPS Journal
- Biacore surface matrix effects on the binding kinetics and affinity of an antigen/antibody complex
- (2012) Andrew W. Drake et al. ANALYTICAL BIOCHEMISTRY
- Physiologically Based Pharmacokinetic (PBPK) Modeling in Children
- (2012) J S Barrett et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Anti-TNF Monoclonal Antibodies in Inflammatory Bowel Disease: Pharmacokinetics-Based Dosing Paradigms
- (2012) I Ordás et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Cytochrome P450 variations in different ethnic populations
- (2012) Joseph McGraw et al. Expert Opinion on Drug Metabolism & Toxicology
- Increasing Serum Half-life and Extending Cholesterol Loweringin Vivoby Engineering Antibody with pH-sensitive Binding to PCSK9
- (2012) Javier Chaparro-Riggers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterizing the Impact of Renal Impairment on the Clinical Pharmacology of Biologics
- (2012) Bernd Meibohm et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Rational development and utilization of antibody-based therapeutic proteins in pediatrics
- (2012) Zhenhua Xu et al. PHARMACOLOGY & THERAPEUTICS
- Quantitative Prediction of Human Pharmacokinetics for Monoclonal Antibodies
- (2011) Jennifer Q. Dong et al. CLINICAL PHARMACOKINETICS
- Disease–Drug–Drug Interaction Involving Tocilizumab and Simvastatin in Patients With Rheumatoid Arthritis
- (2011) C Schmitt et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Pharmacokinetic Properties of Infliximab in Children and Adults with Crohn's Disease: A Retrospective Analysis of Data from 2 Phase III Clinical Trials
- (2011) Adedigbo A. Fasanmade et al. CLINICAL THERAPEUTICS
- Serum albumin concentration: a predictive factor of infliximab pharmacokinetics and clinical response in patients with ulcerative colitis
- (2011) A.A. Fasanmade et al. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
- Projecting human pharmacokinetics of therapeutic antibodies from nonclinical data
- (2011) Rong Deng et al. mAbs
- Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
- (2011) Peter Carmeliet et al. NATURE REVIEWS DRUG DISCOVERY
- Pharmacokinetic-Pharmacodynamic Disease Progression Model for Effect of Etanercept in Lewis Rats with Collagen-Induced Arthritis
- (2011) Hoi-Kei Lon et al. PHARMACEUTICAL RESEARCH
- Prediction of Exposure–Response Relationships to Support First-in-Human Study Design
- (2010) John P. Gibbs AAPS Journal
- Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies
- (2010) Diane R. Mould et al. BIODRUGS
- Population Pharmacokinetics of Therapeutic Monoclonal Antibodies
- (2010) Nathanael L. Dirks et al. CLINICAL PHARMACOKINETICS
- Preclinical development of monoclonal antibodies
- (2010) Kathryn Chapman et al. mAbs
- Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies
- (2010) Frank R. Brennan et al. mAbs
- Anti-infliximab and anti-adalimumab antibodies in relation to response to adalimumab in infliximab switchers and anti-tumour necrosis factor naive patients: a cohort study
- (2009) G. M. Bartelds et al. ANNALS OF THE RHEUMATIC DISEASES
- On Setting the First Dose in Man: Quantitating Biotherapeutic Drug-Target Binding through Pharmacokinetic and Pharmacodynamic Models
- (2009) Philip J. Lowe et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- The minimum anticipated biological effect level (MABEL) for selection of first human dose in clinical trials with monoclonal antibodies
- (2009) Patrick Y Muller et al. CURRENT OPINION IN BIOTECHNOLOGY
- Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis
- (2009) Adedigbo A. Fasanmade et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Fixed Dosing Versus Body Size-Based Dosing of Monoclonal Antibodies in Adult Clinical Trials
- (2009) Diane D. Wang et al. JOURNAL OF CLINICAL PHARMACOLOGY
- The In Silico Child: Using Simulation to Guide Pediatric Drug Development and Manage Pediatric Pharmacotherapy
- (2009) Stephanie Läer et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Concepts and Challenges in Quantitative Pharmacology and Model-Based Drug Development
- (2008) Liping Zhang et al. AAPS Journal
- Tumor burden influences exposure and response to rituximab: pharmacokinetic-pharmacodynamic modeling using a syngeneic bioluminescent murine model expressing human CD20
- (2008) D. Dayde et al. BLOOD
- Clinical pharmacokinetics of bevacizumab in patients with solid tumors
- (2008) Jian-Feng Lu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Engineered Antibodies of IgG1/IgG3 Mixed Isotype with Enhanced Cytotoxic Activities
- (2008) A. Natsume et al. CANCER RESEARCH
- Trastuzumab cardiotoxicity: biological hypotheses and clinical open issues
- (2008) Emilio Bria et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Population Pharmacokinetics of Cetuximab in Patients With Squamous Cell Carcinoma of the Head and Neck
- (2008) Nathanae L. Dirks et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Population Pharmacokinetics of Infliximab in Patients With Ankylosing Spondylitis
- (2008) Zhenhua Xu et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Quantitative Dynamic Models of Arthritis Progression in the Rat
- (2008) Justin C. Earp et al. PHARMACEUTICAL RESEARCH
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now