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Population Pharmacokinetics of Therapeutic Monoclonal Antibodies

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To scale or not to scale: the principles of dose extrapolation

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Interspecies Scaling of Therapeutic Monoclonal Antibodies: Initial Look

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Pharmacokinetic Allometric Scaling of Antibodies: Application to the First-In-Human Dose Estimation

(2009) Iftekhar Mahmood   JOURNAL OF PHARMACEUTICAL SCIENCES

Monoclonal Antibody Pharmacokinetics and Pharmacodynamics

(2008) W Wang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of humanized monoclonal anti-IL-13 antibodies with different IL-13 neutralization mechanisms

(2008) Yulia Vugmeyster et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Role of Fixed Coefficients and Exponents in the Prediction of Human Drug Clearance: How Accurate are the Predictions from One or Two Species?

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