A Nanobody-Conjugated DNA Nanoplatform for Targeted Platinum-Drug Delivery

Facile syntheses of conjugated polymers for photothermal tumour therapy

(2019) Peiyao Chen et al.   Nature Communications

Restraining Cancer Cells by Dual Metabolic Inhibition with a Mitochondrion-Targeted Platinum(II) Complex

(2019) Kun Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembled Double-Bundle DNA Tetrahedron for Efficient Antisense Delivery

(2018) Juanjuan Yang et al.   ACS Applied Materials & Interfaces

Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: So near and yet so far

(2018) Thanuja M.Y. et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanobodies: Chemical Functionalization Strategies and Intracellular Applications

(2018) Dominik Schumacher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Monochalcoplatin: An Actively Transported, Quickly Reducible, and Highly Potent PtIV Anticancer Prodrug

(2018) Lili Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Streptavidin-mirror DNA tetrahedron hybrid as a platform for intracellular and tumor delivery of enzymes

(2018) Kyoung-Ran Kim et al.   JOURNAL OF CONTROLLED RELEASE

On the use of liposome controls in studies investigating the clinical potential of extracellular vesicle-based drug delivery systems – A commentary

(2018) Kasper Bendix Johnsen et al.   JOURNAL OF CONTROLLED RELEASE

A DNA-Based Nanocarrier for Efficient Gene Delivery and Combined Cancer Therapy

(2018) Jianbing Liu et al.   NANO LETTERS

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

Yeast surface display platform for rapid discovery of conformationally selective nanobodies

(2018) Conor McMahon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging

(2018) Benjamin J. Stenton et al.   Chemical Science

A peptide tag-specific nanobody enables high-quality labeling for dSTORM imaging

(2018) David Virant et al.   Nature Communications

Yeast surface display platform for rapid discovery of conformationally selective nanobodies

(2018) Conor McMahon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tumor-Acidity-Cleavable Maleic Acid Amide (TACMAA): A Powerful Tool for Designing Smart Nanoparticles To Overcome Delivery Barriers in Cancer Nanomedicine

(2018) Jin-Zhi Du et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Tailored DNA Nanoplatform for Synergistic RNAi-/Chemotherapy of Multidrug-Resistant Tumors

(2018) Jianbing Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stimuli-Responsive Therapeutic Metallodrugs

(2018) Xiaohui Wang et al.   CHEMICAL REVIEWS

Platinum Intercalators of DNA as Anticancer Agents

(2017) Benjamin J. Pages et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

(2017) Peter M Bruno et al.   NATURE MEDICINE

Cell-targetable DNA nanocapsules for spatiotemporal release of caged bioactive small molecules

(2017) Aneesh T. Veetil et al.   Nature Nanotechnology

EGFR-mediated macrophage activation promotes colitis-associated tumorigenesis

(2017) D M Hardbower et al.   ONCOGENE

The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

(2016) Timothy C. Johnstone et al.   CHEMICAL REVIEWS

Intracellular Delivery of a Planar DNA Origami Structure by the Transferrin-Receptor Internalization Pathway

(2016) David H. Schaffert et al.   Small

Self-Assembly of Molecule-like Nanoparticle Clusters Directed by DNA Nanocages

(2015) Yulin Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The genomic landscape of response to EGFR blockade in colorectal cancer

(2015) Andrea Bertotti et al.   NATURE

Functional DNA-Containing Nanomaterials: Cellular Applications in Biosensing, Imaging, and Targeted Therapy

(2014) Hao Liang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Structural DNA Nanotechnology: State of the Art and Future Perspective

(2014) Fei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

(2014) Yao-Rong Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional DNA Nanostructures for Theranostic Applications

(2013) Hao Pei et al.   ACCOUNTS OF CHEMICAL RESEARCH

Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains

(2013) Karl R. Schmitz et al.   STRUCTURE

DNA Origami Delivery System for Cancer Therapy with Tunable Release Properties

(2012) Yong-Xing Zhao et al.   ACS Nano

Functionalized DNA Nanostructures

(2012) Ofer I. Wilner et al.   CHEMICAL REVIEWS

Cytotoxic platinum(ii) intercalators that incorporate 1R,2R-diaminocyclopentane

(2012) K. Benjamin Garbutcheon-Singh et al.   DALTON TRANSACTIONS

DNA Origami as a Carrier for Circumvention of Drug Resistance

(2012) Qiao Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy

(2012) Ajay Ummat et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo

(2011) Shanta Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A synthetic icosahedral DNA-based host–cargo complex for functional in vivo imaging

(2011) Dhiraj Bhatia et al.   Nature Communications

Advances in Platinum Chemotherapeutics

(2010) Benjamin W. Harper et al.   CHEMISTRY-A EUROPEAN JOURNAL

Studies of the Mechanism of Action of Platinum(II) Complexes with Potent Cytotoxicity in Human Cancer Cells

(2009) Anwen M. Krause-Heuer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

(2008) Wataru Sakai et al.   NATURE

Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra

(2008) Yu He et al.   NATURE