EGFR-mediated macrophage activation promotes colitis-associated tumorigenesis

Colonic macrophage polarization in homeostasis, inflammation, and cancer

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Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection

(2016) Dana M. Hardbower et al.   AMINO ACIDS

EGFR regulates macrophage activation and function in bacterial infection

(2016) Dana M. Hardbower et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional screen identifies regulators of murine hematopoietic stem cell repopulation

(2016) Per Holmfeldt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

(2016) Anna-Maria Georgoudaki et al.   Cell Reports

M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment

(2015) E. Van Overmeire et al.   CANCER RESEARCH

IL-1α induces CD11blowalveolar macrophage proliferation and maturation during granuloma formation

(2015) François Huaux et al.   JOURNAL OF PATHOLOGY

The Global Burden of Cancer 2013

(2015) Christina Fitzmaurice et al.   JAMA Oncology

Activation of EGFR and ERBB2 by Helicobacter pylori Results in Survival of Gastric Epithelial Cells With DNA Damage

(2014) Rupesh Chaturvedi et al.   GASTROENTEROLOGY

Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth

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LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers

(2014) Haiyang Yu et al.   Nature Communications

Regulation of Chemokines, CCL3 and CCL4, by Interferon γ and Nitric Oxide Synthase 2 in Mouse Macrophages and During Salmonella enterica Serovar Typhimurium Infection

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miR-181a Regulates Inflammation Responses in Monocytes and Macrophages

(2013) Weidong Xie et al.   PLoS One

The Role of Epidermal Growth Factor Receptor in Cancer Metastasis and Microenvironment

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Epidermal growth factor receptor inhibits colitis-associated cancer in mice

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MTGR1 Is Required for Tumorigenesis in the Murine AOM/DSS Colitis-Associated Carcinoma Model

(2011) Caitlyn W. Barrett et al.   CANCER RESEARCH

Animal Models of Colitis-Associated Carcinogenesis

(2011) Manasa Kanneganti et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Inflammation and Colon Cancer

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IL-10 regulation of macrophage VEGF production is dependent on macrophage polarisation and hypoxia

(2010) Wei-Kang Wu et al.   IMMUNOBIOLOGY

Interleukin-8 is associated with proliferation, migration, angiogenesis and chemosensitivity in vitro and in vivo in colon cancer cell line models

(2010) Yan Ning et al.   INTERNATIONAL JOURNAL OF CANCER

Constitutive NF- B Activation in Colorectal Carcinoma Plays a Key Role in Angiogenesis, Promoting Tumor Growth

(2009) K. Sakamoto et al.   CLINICAL CANCER RESEARCH

Conditional Deletion of IκB-Kinase-β Accelerates Helicobacter-Dependent Gastric Apoptosis, Proliferation, and Preneoplasia

(2009) Wataru Shibata et al.   GASTROENTEROLOGY

The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies

(2009) J. Hol et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer

(2009) Linda A. Feagins et al.   Nature Reviews Gastroenterology & Hepatology

Modulation of the Intestinal Microbiota Alters Colitis-Associated Colorectal Cancer Susceptibility

(2009) Joshua M. Uronis et al.   PLoS One

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor  B

(2009) C. Porta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Apolipoprotein E-mimetic Peptide COG112 Inhibits the Inflammatory Response toCitrobacter rodentiumin Colonic Epithelial Cells by Preventing NF-κB Activation

(2008) Kshipra Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY