The NAE Pathway: Autobahn to the Nucleus for Cell Surface Receptors

Anaphylactic Degranulation of Mast Cells: Focus on Compound Exocytosis

(2019) Ofir Klein et al.   Journal of Immunology Research

Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression

(2019) Melissa L. Hancock et al.   CELL

Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling

(2019) Roberta Pascolutti et al.   Cell Reports

The basic route of the nuclear translocation porcine growth hormone (GH)-growth hormone receptor (GHR) complex (pGH/GHR) in porcine hepatocytes

(2018) Lan Hainan et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element–modifying factor 1

(2018) Natalia Papadopoulos et al.   JOURNAL OF CELL BIOLOGY

The enigmatic endosome – sorting the ins and outs of endocytic trafficking

(2018) Naava Naslavsky et al.   JOURNAL OF CELL SCIENCE

Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum

(2018) Katharina Braunger et al.   SCIENCE

The Drosophila Epidermal Growth Factor Receptor does not act in the nucleus

(2018) Maximilien Courgeon et al.   JOURNAL OF CELL SCIENCE

An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases

(2017) Sven Lang et al.   Frontiers in Physiology

Endoplasmic Reticulum–Associated Degradation and Lipid Homeostasis

(2016) Julian Stevenson et al.   Annual Review of Nutrition

Effects of different ligands on epidermal growth factor receptor (EGFR) nuclear translocation

(2016) Jerusa A.Q.A. Faria et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The formation and function of ER-endosome membrane contact sites

(2016) Emily R. Eden   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer

(2016) Jennifer L. Hsu et al.   CANCER AND METASTASIS REVIEWS

Lysosomal signaling in control of degradation pathways

(2016) Lukas A Huber et al.   CURRENT OPINION IN CELL BIOLOGY

Analysis of membrane proteins localizing to the inner nuclear envelope in living cells

(2016) Christine J. Smoyer et al.   JOURNAL OF CELL BIOLOGY

Bidirectional traffic between the Golgi and the endosomes – machineries and regulation

(2016) Cinzia Progida et al.   JOURNAL OF CELL SCIENCE

Nuclear envelope-associated endosomes deliver surface proteins to the nucleus

(2015) Alexandre Chaumet et al.   Nature Communications

Ricin Trafficking in Cells

(2015) Robert Spooner et al.   Toxins

Pseudomonas Exotoxin A: optimized by evolution for effective killing

(2015) Marta Michalska et al.   Frontiers in Microbiology

Arf GTPases and their effectors: assembling multivalent membrane-binding platforms

(2014) Jacqueline Cherfils   CURRENT OPINION IN STRUCTURAL BIOLOGY

EGFR Modulates DNA Synthesis and Repair through Tyr Phosphorylation of Histone H4

(2014) Ruey-Hwang Chou et al.   DEVELOPMENTAL CELL

Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance

(2014) R I Cordo Russo et al.   ONCOGENE

The role of the cytoskeleton and molecular motors in endosomal dynamics

(2014) Elizabeth Granger et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Function and Regulation of the Endosomal Fusion and Fission Machineries

(2014) A. Gautreau et al.   Cold Spring Harbor Perspectives in Biology

Contact of cis-Golgi with ER exit sites executes cargo capture and delivery from the ER

(2014) Kazuo Kurokawa et al.   Nature Communications

LDL Receptor–Related Protein-1

(2013) Steven L. Gonias et al.   AMERICAN JOURNAL OF PATHOLOGY

Nuclear Positioning

(2013) Gregg G. Gundersen et al.   CELL

Threshold-controlled ubiquitination of the EGFR directs receptor fate

(2013) Sara Sigismund et al.   EMBO JOURNAL

Nesprins: from the nuclear envelope and beyond

(2013) Dipen Rajgor et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The insulin receptor translocates to the nucleus to regulate cell proliferation in liver

(2013) Maria J. Amaya et al.   HEPATOLOGY

Golgi’s way: a long path toward the new paradigm of the intra-Golgi transport

(2013) Alexander A. Mironov et al.   HISTOCHEMISTRY AND CELL BIOLOGY

CD4 and BST-2/Tetherin Proteins Retro-translocate from Endoplasmic Reticulum to Cytosol as Partially Folded and Multimeric Molecules

(2013) Gianluca Petris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear EGFR protein expression predicts poor survival in early stage non-small cell lung cancer

(2013) Anne M. Traynor et al.   LUNG CANCER

ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus

(2013) Waka Nakai et al.   MOLECULAR BIOLOGY OF THE CELL

Targeting the EGFR/PCNA Signaling Suppresses Tumor Growth of Triple-Negative Breast Cancer Cells with Cell-Penetrating PCNA Peptides

(2013) Yung-Luen Yu et al.   PLoS One

Nuclear EGFR as a molecular target in cancer

(2013) Toni M. Brand et al.   RADIOTHERAPY AND ONCOLOGY

EGF receptor trafficking: consequences for signaling and cancer

(2013) Alejandra Tomas et al.   TRENDS IN CELL BIOLOGY

Destination: inner nuclear membrane

(2013) Santharam S. Katta et al.   TRENDS IN CELL BIOLOGY

Retrograde Traffic from the Golgi to the Endoplasmic Reticulum

(2013) A. Spang   Cold Spring Harbor Perspectives in Biology

Protein tyrosine kinase regulation by ubiquitination: Critical roles of Cbl-family ubiquitin ligases

(2012) Bhopal Mohapatra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer

(2012) Roxana Schillaci et al.   BMC CANCER

LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins

(2012) Brian A. Sosa et al.   CELL

Governance of Endocytic Trafficking and Signaling by Reversible Ubiquitylation

(2012) Michael J. Clague et al.   DEVELOPMENTAL CELL

Palmitoylated calnexin is a key component of the ribosome-translocon complex

(2012) Asvin KK Lakkaraju et al.   EMBO JOURNAL

The Human Nuclear Pore Complex as Revealed by Cryo-Electron Tomography

(2012) Tal Maimon et al.   STRUCTURE

The DSL1 Complex: The Smallest but Not the Least CATCHR

(2012) Anne Spang   TRAFFIC

The transport of integral membrane proteins across the nuclear pore complex

(2012) Anne C. Meinema et al.   Nucleus

Epidermal growth factor receptors destined for the nucleus are internalized via a clathrin-dependent pathway

(2011) Ana Carolina De Angelis Campos et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nuclear ErbB2 Enhances Translation and Cell Growth by Activating Transcription of Ribosomal RNA Genes

(2011) L.-Y. Li et al.   CANCER RESEARCH

EGFR Nuclear Translocation Modulates DNA Repair following Cisplatin and Ionizing Radiation Treatment

(2011) G. Liccardi et al.   CANCER RESEARCH

KASH and SUN proteins

(2011) Daniel A. Starr   CURRENT BIOLOGY

Genome-Wide RNAi Screens Identify Genes Required for Ricin and PE Intoxications

(2011) Dimitri Moreau et al.   DEVELOPMENTAL CELL

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

The Dsl1 Protein Tethering Complex Is a Resident Endoplasmic Reticulum Complex, Which Interacts with Five Soluble NSF (N-Ethylmaleimide-sensitive Factor) Attachment Protein Receptors (SNAREs)

(2011) Christoph T. A. Meiringer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Translocation of Epidermal Growth Factor Receptor by Akt-dependent Phosphorylation Enhances Breast Cancer-resistant Protein Expression in Gefitinib-resistant Cells

(2011) Wei-Chien Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol

(2011) Roger Geiger et al.   NATURE CELL BIOLOGY

Deubiquitination of EGFR by Cezanne-1 contributes to cancer progression

(2011) F Pareja et al.   ONCOGENE

VEGFR2 Translocates to the Nucleus to Regulate Its Own Transcription

(2011) Inês Domingues et al.   PLoS One

COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport

(2010) Ying-Nai Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nuclear localization of orphan receptor protein kinase (Ror1) is mediated through the juxtamembrane domain

(2010) Hsiao-Chun Tseng et al.   BMC CELL BIOLOGY

A classical NLS and the SUN domain contribute to the targeting of SUN2 to the inner nuclear membrane

(2010) Yagmur Turgay et al.   EMBO JOURNAL

Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654

(2010) Klaus Dittmann et al.   FEBS LETTERS

Transportin Regulates Nuclear Import of CD44

(2010) Michalina Janiszewska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Translocon Sec61β Localized in the Inner Nuclear Membrane Transports Membrane-embedded EGF Receptor to the Nucleus

(2010) Ying-Nai Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

(2010) Lai Kuan Goh et al.   JOURNAL OF CELL BIOLOGY

Nuclear trafficking of the epidermal growth factor receptor family membrane proteins

(2010) Y-N Wang et al.   ONCOGENE

Shiga Toxins: Intracellular Trafficking to the ER Leading to Activation of Host Cell Stress Responses

(2010) Moo-Seung Lee et al.   Toxins

Cholera Toxin: An Intracellular Journey into the Cytosol by Way of the Endoplasmic Reticulum

(2010) Naomi L. B. Wernick et al.   Toxins

Acetylation and activation of STAT3 mediated by nuclear translocation of CD44

(2009) Jia-Lin Lee et al.   JOURNAL OF CELL BIOLOGY

Ultraviolet irradiation-induces epidermal growth factor receptor (EGFR) nuclear translocation in human keratinocytes

(2009) Yiru Xu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes

(2009) Takeshi Ohya et al.   NATURE

Nuclear EGFR contributes to acquired resistance to cetuximab

(2009) C Li et al.   ONCOGENE

G Protein-Coupled Receptors in and on the Cell Nucleus: A New Signaling Paradigm?

(2008) BENOIT BOIVIN et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer

(2008) Weiya Xia et al.   MOLECULAR CARCINOGENESIS

Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression

(2008) Liang-Yi Hung et al.   NUCLEIC ACIDS RESEARCH

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

(2008) Anna P. Lillis et al.   PHYSIOLOGICAL REVIEWS

The Recognition and Retrotranslocation of Misfolded Proteins from the Endoplasmic Reticulum

(2008) Kunio Nakatsukasa et al.   TRAFFIC