Threshold-controlled ubiquitination of the EGFR directs receptor fate

Governance of Endocytic Trafficking and Signaling by Reversible Ubiquitylation

(2012) Michael J. Clague et al.   DEVELOPMENTAL CELL

Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl

(2012) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation

(2011) Elena Maspero et al.   EMBO REPORTS

Feedback regulation of EGFR signalling: decision making by early and delayed loops

(2011) Roi Avraham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Chimeric Pre-ubiquitinated EGF Receptor is Constitutively Endocytosed in a Clathrin-Dependent, but Kinase-Independent Manner

(2011) Vibeke Bertelsen et al.   TRAFFIC

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

(2010) Lai Kuan Goh et al.   JOURNAL OF CELL BIOLOGY

Internalization and intracellular sorting of the EGF receptor: a model for understanding the mechanisms of receptor trafficking

(2009) I. H. Madshus et al.   JOURNAL OF CELL SCIENCE

Endocytic trafficking of activated EGFR is AP-2 dependent and occurs through preformed clathrin spots

(2009) J. Z. Rappoport et al.   JOURNAL OF CELL SCIENCE

Robust Generation and Decoding of Morphogen Gradients

(2009) N. Barkai et al.   Cold Spring Harbor Perspectives in Biology

An ultrasensitive sorting mechanism for EGF Receptor Endocytosis

(2008) Hannah Schmidt-Glenewinkel et al.   BMC Systems Biology

Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

(2008) Sara Sigismund et al.   DEVELOPMENTAL CELL

Endocytosis and intracellular trafficking of ErbBs

(2008) Alexander Sorkin et al.   EXPERIMENTAL CELL RESEARCH

Ubc4/5 and c-Cbl Continue to Ubiquitinate EGF Receptor after Internalization to Facilitate Polyubiquitination and Degradation

(2008) Kyohei Umebayashi et al.   MOLECULAR BIOLOGY OF THE CELL