Ricin Trafficking in Cells

Protein Disulfide-Isomerase Interacts with a Substrate Protein at All Stages along Its Folding Pathway

(2014) Alistair G. Irvine et al.   PLoS One

The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain

(2013) Paola Pietroni et al.   BIOCHEMICAL JOURNAL

The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol

(2013) Monika Słomińska-Wojewódzka et al.   BIOCHEMICAL JOURNAL

Novel Class of Potential Therapeutics that Target Ricin Retrograde Translocation

(2013) Veronika Redmann et al.   Toxins

BiP Negatively Affects Ricin Transport

(2013) Tone Gregers et al.   Toxins

Reductive Activation of Type 2 Ribosome-inactivating Proteins Is Promoted by Transmembrane Thioredoxin-related Protein

(2012) Matteo Pasetto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytosolic Entry of Shiga-Like Toxin A Chain from the Yeast Endoplasmic Reticulum Requires Catalytically Active Hrd1p

(2012) Shuyu Li et al.   PLoS One

Annexin A1 and A2: Roles in Retrograde Trafficking of Shiga Toxin

(2012) Lionel Tcatchoff et al.   PLoS One

N-glycosylation Does Not Affect the Catalytic Activity of Ricin A Chain but Stimulates Cytotoxicity by Promoting Its Transport Out of the Endoplasmic Reticulum

(2012) Qing Yan et al.   TRAFFIC

A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation

(2011) Iwona Sokołowska et al.   BIOCHEMICAL JOURNAL

Rapid membrane protein topology prediction

(2011) Aron Hennerdal et al.   BIOINFORMATICS

Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells

(2011) Ulrich Elling et al.   Cell Stem Cell

Dislocation of Ricin Toxin A Chains in Human Cells Utilizes Selective Cellular Factors

(2011) Veronika Redmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

Derlin-Dependent Retrograde Transport from Endosomes to the Golgi Apparatus

(2011) Hope Dang et al.   TRAFFIC

Ubiquitylation in ERAD: Reversing to Go Forward?

(2011) Yien Che Tsai et al.   PLOS BIOLOGY

Enzymatic Blockade of the Ubiquitin-Proteasome Pathway

(2011) Robert Ernst et al.   PLOS BIOLOGY

p24 proteins from the same subfamily are functionally nonredundant

(2010) Jeroen R.P.M. Strating et al.   BIOCHIMIE

Hsp90 Is Required for Transfer of the Cholera Toxin A1 Subunit from the Endoplasmic Reticulum to the Cytosol

(2010) Michael Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modularity of the Hrd1 ERAD complex underlies its diverse client range

(2010) Kazue Kanehara et al.   JOURNAL OF CELL BIOLOGY

Folding-competent and Folding-defective Forms of Ricin A Chain Have Different Fates after Retrotranslocation from the Endoplasmic Reticulum

(2010) Shuyu Li et al.   MOLECULAR BIOLOGY OF THE CELL

Interplay between Toxin Transport and Flotillin Localization

(2010) Sascha Pust et al.   PLoS One

The p24 family and selective transport processes at the ER-Golgi interface

(2009) Jeroen R.P.M. Strating et al.   BIOLOGY OF THE CELL

ER exit sites - Localization and control of COPII vesicle formation

(2009) Annika Budnik et al.   FEBS LETTERS

A Human Embryonic Kidney 293T Cell Line Mutated at the Golgi α-Mannosidase II Locus

(2009) Max Crispin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ricin A Chain Insertion into Endoplasmic Reticulum Membranes Is Triggered by a Temperature Increase to 37 °C

(2009) Peter U. Mayerhofer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Misfolded Membrane Proteins Are Specifically Recognized by the Transmembrane Domain of the Hrd1p Ubiquitin Ligase

(2009) Brian K. Sato et al.   MOLECULAR CELL

TOPCONS: consensus prediction of membrane protein topology

(2009) A. Bernsel et al.   NUCLEIC ACIDS RESEARCH

The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and thetrans-Golgi network

(2008) Robert A. Spooner et al.   BIOCHEMICAL JOURNAL

Ricin Inhibits Activation of the Unfolded Protein Response by Preventing Splicing of theHAC1mRNA

(2008) Bijal A. Parikh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Proteasomal ATPase Contributes to Dislocation of Endoplasmic Reticulum-associated Degradation (ERAD) Substrates

(2008) Carni Lipson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bap31 Is an Itinerant Protein That Moves between the Peripheral Endoplasmic Reticulum (ER) and a Juxtanuclear Compartment Related to ER-associated Degradation

(2008) Yuichi Wakana et al.   MOLECULAR BIOLOGY OF THE CELL

Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum

(2008) R. A. Spooner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA