CD4 and BST-2/Tetherin Proteins Retro-translocate from Endoplasmic Reticulum to Cytosol as Partially Folded and Multimeric Molecules

Decoupling the Role of Ubiquitination for the DislocationVersusDegradation of Major Histocompatibility Complex (MHC) Class I Proteins during Endoplasmic Reticulum-associated Degradation (ERAD)

(2013) Xiaoli Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Finding the will and the way of ERAD substrate retrotranslocation

(2012) Randolph Y Hampton et al.   CURRENT OPINION IN CELL BIOLOGY

Selective Targeting of Proteins within Secretory Pathway for Endoplasmic Reticulum-associated Degradation

(2012) Lara Vecchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytosolic Entry of Shiga-Like Toxin A Chain from the Yeast Endoplasmic Reticulum Requires Catalytically Active Hrd1p

(2012) Shuyu Li et al.   PLoS One

A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation

(2011) Iwona Sokołowska et al.   BIOCHEMICAL JOURNAL

Lipid Droplet Formation Is Dispensable for Endoplasmic Reticulum-associated Degradation

(2011) James A. Olzmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of an ERAD Pathway Mediated by the ER-Resident Protein Disulfide Reductase ERdj5

(2011) Masatoshi Hagiwara et al.   MOLECULAR CELL

BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol

(2011) Roger Geiger et al.   NATURE CELL BIOLOGY

Efficient Detection of Proteins Retro-Translocated from the ER to the Cytosol by In Vivo Biotinylation

(2011) Gianluca Petris et al.   PLoS One

Protein quality control in the ER: balancing the ubiquitin checkbook

(2011) Jasper H.L. Claessen et al.   TRENDS IN CELL BIOLOGY

Protein dislocation from the ER

(2010) Katrin Bagola et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structural Basis of HIV-1 Tethering to Membranes by the BST-2/Tetherin Ectodomain

(2010) Andreas Hinz et al.   Cell Host & Microbe

ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER

(2010) Riccardo Bernasconi et al.   CURRENT OPINION IN CELL BIOLOGY

Disulfide bonds in ER protein folding and homeostasis

(2010) Matthias J Feige et al.   CURRENT OPINION IN CELL BIOLOGY

TRAM1 is involved in disposal of ER membrane degradation substrates

(2010) Caroline L. Ng et al.   EXPERIMENTAL CELL RESEARCH

Human Perforin Employs Different Avenues to Damage Membranes

(2010) Tilen Praper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Biophysical Analysis of BST-2/Tetherin Ectodomains Reveals an Evolutionary Conserved Design to Inhibit Virus Release

(2010) Melissa Swiecki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compartment-Restricted Biotinylation Reveals Novel Features of Prion Protein Metabolism in Vivo

(2010) Amy B. Emerman et al.   MOLECULAR BIOLOGY OF THE CELL

The structural basis for membrane binding and pore formation by lymphocyte perforin

(2010) Ruby H. P. Law et al.   NATURE

A minimal peptide substrate in biotin holoenzyme synthetase-catalyzed biotinylation

(2010) Dorothy Beckett et al.   PROTEIN SCIENCE

Multilayered Mechanism of CD4 Downregulation by HIV-1 Vpu Involving Distinct ER Retention and ERAD Targeting Steps

(2010) Javier G. Magadán et al.   PLoS Pathogens

Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells

(2009) David Perez-Caballero et al.   CELL

HIV-1 Antagonism of CD317 Is Species Specific and Involves Vpu-Mediated Proteasomal Degradation of the Restriction Factor

(2009) Christine Goffinet et al.   Cell Host & Microbe

HIV-1 Accessory Protein Vpu Internalizes Cell-surface BST-2/Tetherin through Transmembrane Interactions Leading to Lysosomes

(2009) Yukie Iwabu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vpu Directs the Degradation of the Human Immunodeficiency Virus Restriction Factor BST-2/Tetherin via a  TrCP-Dependent Mechanism

(2009) J. L. Douglas et al.   JOURNAL OF VIROLOGY

HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent Degradation

(2009) Bastien Mangeat et al.   PLoS Pathogens

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

(2009) Richard S. Mitchell et al.   PLoS Pathogens

In vivo site-specific biotinylation of proteins within the secretory pathway using a single vector system

(2008) Andrea Predonzani et al.   BMC BIOTECHNOLOGY

BAP31 Interacts with Sec61 Translocons and Promotes Retrotranslocation of CFTRΔF508 via the Derlin-1 Complex

(2008) Bing Wang et al.   CELL

Inhibition of Lassa and Marburg Virus Production by Tetherin

(2008) T. Sakuma et al.   JOURNAL OF VIROLOGY

Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin

(2008) N. Jouvenet et al.   JOURNAL OF VIROLOGY

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER

(2008) R. Ushioda et al.   SCIENCE