Tissue Response to Neural Implants: The Use of Model Systems Toward New Design Solutions of Implantable Microelectrodes

Deep Brain Stimulation for Obsessive Compulsive Disorder: Evolution of Surgical Stimulation Target Parallels Changing Model of Dysfunctional Brain Circuits

(2019) Patrick J. Karas et al.   Frontiers in Neuroscience

Modeling traumatic injury in organotypic spinal cord slice culture obtained from adult rat

(2019) Sareh Pandamooz et al.   TISSUE & CELL

High-Performance Graphene-Fiber-Based Neural Recording Microelectrodes

(2019) Kezhong Wang et al.   ADVANCED MATERIALS

Blood brain barrier (BBB)-disruption in intracortical silicon microelectrode implants

(2018) Cassie Bennett et al.   BIOMATERIALS

In vivo spatiotemporal dynamics of NG2 glia activity caused by neural electrode implantation

(2018) Steven M. Wellman et al.   BIOMATERIALS

In vivo imaging of neuronal calcium during electrode implantation: Spatial and temporal mapping of damage and recovery

(2018) James R. Eles et al.   BIOMATERIALS

Targeting CD14 on blood derived cells improves intracortical microelectrode performance

(2018) Hillary W. Bedell et al.   BIOMATERIALS

Deep brain stimulation for stroke: Current uses and future directions

(2018) Gavin J.B. Elias et al.   Brain Stimulation

Vascularized microfluidic organ-chips for drug screening, disease models and tissue engineering

(2018) Tatsuya Osaki et al.   CURRENT OPINION IN BIOTECHNOLOGY

Deep brain stimulation for epilepsy

(2018) Vicenta Salanova   EPILEPSY & BEHAVIOR

Disease Modeling Using 3D Organoids Derived from Human Induced Pluripotent Stem Cells

(2018) Beatrice Ho et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of the cluster of differentiation 14 innate immunity pathway with IAXO-101 improves chronic microelectrode performance

(2018) John K Hermann et al.   Journal of Neural Engineering

The development of neural stimulators: a review of preclinical safety and efficacy studies

(2018) Robert K Shepherd et al.   Journal of Neural Engineering

Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening

(2018) Daniela M. Magalhães et al.   Journal of Neuroinflammation

A novel ex vivo method for measuring whole brain metabolism in model systems

(2018) Kathryn E. Neville et al.   JOURNAL OF NEUROSCIENCE METHODS

Fibrotic scarring following lesions to the central nervous system

(2018) David Oliveira Dias et al.   MATRIX BIOLOGY

Deep brain stimulation for treatment-resistant depression: an integrative review of preclinical and clinical findings and translational implications

(2018) M P Dandekar et al.   MOLECULAR PSYCHIATRY

DBS of the PSA and the VIM in essential tremor

(2018) Michael T. Barbe et al.   NEUROLOGY

Long-Term Culture of Organotypic Hippocampal Slice from Old 3xTg-AD Mouse: An ex vivo Model of Alzheimer’s Disease

(2018) Sooah Jang et al.   Psychiatry Investigation

Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics

(2018) Shuo Chen et al.   SCIENCE

In Vitro Screening for Seizure Liability Using Microelectrode Array Technology

(2018) Jenifer A Bradley et al.   TOXICOLOGICAL SCIENCES

Nanowire arrays restore vision in blind mice

(2018) Jing Tang et al.   Nature Communications

Pheochromocytoma (PC12) Cell Response on Mechanobactericidal Titanium Surfaces

(2018) Jason Wandiyanto et al.   Materials

High-performance, polymer-based direct cellular interfaces for electrical stimulation and recording

(2018) Seong-Min Kim et al.   NPG Asia Materials

Engineering stem cell-derived 3D brain organoids in a perfusable organ-on-a-chip system

(2018) Yaqing Wang et al.   RSC Advances

A Mosquito Inspired Strategy to Implant Microprobes into the Brain

(2018) Andrew J. Shoffstall et al.   Scientific Reports

Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling

(2018) Goodwell Nzou et al.   Scientific Reports

PrismPlus: a mouse line expressing distinct fluorophores in four different brain cell types

(2018) Janak Gaire et al.   Scientific Reports

A micro-CT-based method for quantitative brain lesion characterization and electrode localization

(2018) Javier Masís et al.   Scientific Reports

Deep Brain Stimulation for Essential Tremor: A Comparison of Targets

(2018) Joost A.H. Holslag et al.   World Neurosurgery

Globus Pallidus Interna or Subthalamic Nucleus Deep Brain Stimulation for Parkinson Disease

(2018) Adolfo Ramirez-Zamora et al.   JAMA Neurology

Efficacy and Safety of Deep Brain Stimulation in Tourette Syndrome

(2018) Daniel Martinez-Ramirez et al.   JAMA Neurology

A Miniaturized, Programmable Deep-Brain Stimulator for Group-Housing and Water Maze Use

(2018) Richard C. Pinnell et al.   Frontiers in Neuroscience

Engineering Brain Organoids to Probe Impaired Neurogenesis Induced by Cadmium

(2018) Fangchao Yin et al.   ACS Biomaterials-Science & Engineering

Translational potential of human brain organoids

(2018) Alfred X. Sun et al.   Annals of Clinical and Translational Neurology

Engineering Brain Organoids to Probe Impaired Neurogenesis Induced by Cadmium

(2018) Fangchao Yin et al.   ACS Biomaterials Science & Engineering

Modeling Neuropsychiatric and Neurodegenerative Diseases With Induced Pluripotent Stem Cells

(2018) Elizabeth A. LaMarca et al.   Frontiers in Pediatrics

Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons

(2018) Halil Tekin et al.   Nature Biomedical Engineering

The role of oligodendrocytes and their progenitors on neural interface technology: A novel perspective on tissue regeneration and repair

(2018) Steven M. Wellman et al.   BIOMATERIALS

Epilepsy-on-a-chip System for Antiepileptic Drug Discovery

(2018) Jing Liu et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Effect of nanostructures on anchoring stem cell-derived neural tissue to artificial surfaces

(2018) Z Bérces et al.   Journal of Neural Engineering

The role of inflammation on the functionality of intracortical microelectrodes

(2018) Janak Gaire et al.   Journal of Neural Engineering

Nanotopography regulates motor neuron differentiation of human pluripotent stem cells

(2018) Weiqiang Chen et al.   Nanoscale

Configuration of electrical spinal cord stimulation through real-time processing of gait kinematics

(2018) Marco Capogrosso et al.   Nature Protocols

PEDOT: PSS coating on gold microelectrodes with excellent stability and high charge injection capacity for chronic neural interfaces

(2018) Anmona S. Pranti et al.   SENSORS AND ACTUATORS B-CHEMICAL

Characterization of the Neuroinflammatory Response to Thiol-ene Shape Memory Polymer Coated Intracortical Microelectrodes

(2018) Andrew Shoffstall et al.   Micromachines

Development and Characterization of PEDOT:PSS/Alginate Soft Microelectrodes for Application in Neuroprosthetics

(2018) Laura Ferlauto et al.   Frontiers in Neuroscience

Microfabricated intracortical extracellular matrix-microelectrodes for improving neural interfaces

(2018) Wen Shen et al.   Microsystems & Nanoengineering

Chronic fornix deep brain stimulation in a transgenic Alzheimer’s rat model reduces amyloid burden, inflammation, and neuronal loss

(2018) Aurelie Leplus et al.   Brain Structure & Function

Calcium activation of cortical neurons by continuous electrical stimulation: Frequency dependence, temporal fidelity, and activation density

(2018) Nicholas J. Michelson et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Importance of organoids for personalized medicine

(2018) Lukas Perkhofer et al.   Personalized Medicine

Biomimetic extracellular matrix coatings improve the chronic biocompatibility of microfabricated subdural microelectrode arrays

(2018) Flavia Vitale et al.   PLoS One

Microglia innately develop within cerebral organoids

(2018) Paul R. Ormel et al.   Nature Communications

A Bidirectional Neuromodulation Technology for Nerve Recording and Stimulation

(2018) Jian Xu et al.   Micromachines

Understanding the Effects of Both CD14-Mediated Innate Immunity and Device/Tissue Mechanical Mismatch in the Neuroinflammatory Response to Intracortical Microelectrodes

(2018) Hillary W. Bedell et al.   Frontiers in Neuroscience

Meningeal inflammatory response and fibrous tissue remodeling around intracortical implants: An in vivo two-photon imaging study

(2018) J.R. Eles et al.   BIOMATERIALS

Deep brain stimulation targets for treating depression

(2018) Dominik Drobisz et al.   BEHAVIOURAL BRAIN RESEARCH

In vitro study of central nervous system foreign body response towards hydrogel particle modified planar substrate

(2017) Emily A. Morin et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Histological evaluation of flexible neural implants; flexibility limit for reducing the tissue response?

(2017) Heui Chang Lee et al.   Journal of Neural Engineering

Restoration of motor control and proprioceptive and cutaneous sensation in humans with prior upper-limb amputation via multiple Utah Slanted Electrode Arrays (USEAs) implanted in residual peripheral arm nerves

(2017) Suzanne Wendelken et al.   Journal of NeuroEngineering and Rehabilitation

Pallidal deep brain stimulation for dystonia: a long term study

(2017) Sara Meoni et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Development of a head-mounted wireless microstimulator for deep brain stimulation in rats

(2017) Felix Fluri et al.   JOURNAL OF NEUROSCIENCE METHODS

Strong Correlation of Genome-Wide Expression after Traumatic Brain Injury In Vitro and In Vivo Implicates a Role for SORLA

(2017) Michael R. Lamprecht et al.   JOURNAL OF NEUROTRAUMA

Array Focal Cortical Stimulation Enhances Motor Function Recovery and Brain Remodeling in a Rat Model of Ischemia

(2017) Jing Yang et al.   Journal of Stroke & Cerebrovascular Diseases

A three dimensional in vitro glial scar model to investigate the local strain effects from micromotion around neural implants

(2017) Kevin C. Spencer et al.   LAB ON A CHIP

A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood–brain barrier

(2017) Giulia Adriani et al.   LAB ON A CHIP

Attenuation of the in vitro neurotoxicity of 316L SS by graphene oxide surface coating

(2017) Nishat Tasnim et al.   Materials Science & Engineering C-Materials for Biological Applications

Photochemical coating of Kapton® with hydrophilic polymers for the improvement of neural implants

(2017) Christoph Hadler et al.   Materials Science & Engineering C-Materials for Biological Applications

The SH-SY5Y cell line in Parkinson’s disease research: a systematic review

(2017) Helena Xicoy et al.   Molecular Neurodegeneration

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Long-Term Effects of Anterior Thalamic Nucleus Deep Brain Stimulation on Spatial Learning in the Pilocarpine Model of Temporal Lobe Epilepsy

(2017) Elenn Soares Ferreira et al.   NEUROMODULATION

Thinking Small: Progress on Microscale Neurostimulation Technology

(2017) Joseph J. Pancrazio et al.   NEUROMODULATION

DMSO modulates CNS function in a preclinical Alzheimer's disease model

(2017) Lorène Penazzi et al.   NEUROPHARMACOLOGY

Postoperative lead migration in deep brain stimulation surgery: Incidence, risk factors, and clinical impact

(2017) Takashi Morishita et al.   PLoS One

The soft mechanical signature of glial scars in the central nervous system

(2017) Emad Moeendarbary et al.   Nature Communications

Interfacing neurons on carbon nanotubes covered with diamond

(2017) Silke Seyock et al.   RSC Advances

PEDOT:PSS microelectrode arrays for hippocampal cell culture electrophysiological recordings

(2017) Dimitrios A. Koutsouras et al.   MRS Communications

Two-photon calcium imaging of the medial prefrontal cortex and hippocampus without cortical invasion

(2017) Masashi Kondo et al.   eLife

Topographical impact of silver nanolines on the morphology of neuronal SH-SY5Y Cells

(2017) Ifat Nissan et al.   Journal of Materials Chemistry B

Array Focal Cortical Stimulation Enhances Motor Function Recovery and Brain Remodeling in a Rat Model of Ischemia

(2017) Jing Yang et al.   Journal of Stroke & Cerebrovascular Diseases

Deep Brain Stimulation of Hemiparkinsonian Rats with Unipolar and Bipolar Electrodes for up to 6 Weeks: Behavioral Testing of Freely Moving Animals

(2017) Kathrin Badstuebner et al.   Parkinsons Disease

Organotypic brain explant culture as a drug evaluation system for malignant brain tumors

(2017) Noriaki Minami et al.   Cancer Medicine

Neural Interfaces for Intracortical Recording: Requirements, Fabrication Methods, and Characteristics

(2017) Katarzyna M. Szostak et al.   Frontiers in Neuroscience

Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders

(2017) Elke Gabriel et al.   Jove-Journal of Visualized Experiments

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

(2017) Kyle M. Koss et al.   Jove-Journal of Visualized Experiments

Adapting tissue-engineered in vitro CNS models for high-throughput study of neurodegeneration

(2017) Caitriona O’Rourke et al.   Journal of Tissue Engineering

Nano-topography Enhances Communication in Neural Cells Networks

(2017) V. Onesto et al.   Scientific Reports

A Low Permeability Microfluidic Blood-Brain Barrier Platform with Direct Contact between Perfusable Vascular Network and Astrocytes

(2017) Seokyoung Bang et al.   Scientific Reports

Motor recovery after activity-based training with spinal cord epidural stimulation in a chronic motor complete paraplegic

(2017) Enrico Rejc et al.   Scientific Reports

Multifunctional hydrogel coatings on the surface of neural cuff electrode for improving electrode-nerve tissue interfaces

(2016) Dong Nyoung Heo et al.   Acta Biomaterialia

Asynchronous Distributed Multielectrode Microstimulation Reduces Seizures in the Dorsal Tetanus Toxin Model of Temporal Lobe Epilepsy

(2016) Sharanya Arcot Desai et al.   Brain Stimulation

Mechanisms of Reduced Astrocyte Surface Coverage in Cortical Neuron-Glia Co-cultures on Nanoporous Gold Surfaces

(2016) Christopher A. R. Chapman et al.   Cellular and Molecular Bioengineering

Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research

(2016) Martin Engel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nanotopography promoted neuronal differentiation of human induced pluripotent stem cells

(2016) Liqing Song et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

High-throughput platforms for the screening of new therapeutic targets for neurodegenerative diseases

(2016) Daniela N. Rocha et al.   DRUG DISCOVERY TODAY

Developments in 3D neural cell culture models: the future of neurotherapeutics testing?

(2016) Kristin Robin Ko et al.   Expert Review of Neurotherapeutics

Thin-film micro-electrode stimulation of the cochlea in rats exposed to aminoglycoside induced hearing loss

(2016) B.J. Allitt et al.   HEARING RESEARCH

In vitro cyto-biocompatibility study of thin-film transistors substrates using an organotypic culture method

(2016) Eric Leclerc et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Clinical applications of penetrating neural interfaces and Utah Electrode Array technologies

(2016) Richard A Normann et al.   Journal of Neural Engineering

Correlations between histology and neuronal activity recorded by microelectrodes implanted chronically in the cerebral cortex

(2016) Douglas McCreery et al.   Journal of Neural Engineering

Human brain slices for epilepsy research: Pitfalls, solutions and future challenges

(2016) Roland S.G. Jones et al.   JOURNAL OF NEUROSCIENCE METHODS

Poly(3,4-ethylenedioxythiophene):GlycosAminoGlycan Aqueous Dispersions: Toward Electrically Conductive Bioactive Materials for Neural Interfaces

(2016) Daniele Mantione et al.   MACROMOLECULAR BIOSCIENCE

Optimization of a Michigan-type silicon microprobe for infrared neural stimulation

(2016) M. Kiss et al.   SENSORS AND ACTUATORS B-CHEMICAL

Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke

(2016) Michael J. Van Kanegan et al.   Scientific Reports

Developments in 3D neural cell culture models: the future of neurotherapeutics testing?

(2016) Kristin Robin Ko et al.   Expert Review of Neurotherapeutics

Flexible, Penetrating Brain Probes Enabled by Advances in Polymer Microfabrication

(2016) Ahuva Weltman et al.   Micromachines

A Device for Long-Term Perfusion, Imaging, and Electrical Interfacing of Brain Tissue In vitro

(2016) Nathaniel J. Killian et al.   Frontiers in Neuroscience

Mechanical and Biological Interactions of Implants with the Brain and Their Impact on Implant Design

(2016) Dimiter Prodanov et al.   Frontiers in Neuroscience

3D meshes of carbon nanotubes guide functional reconnection of segregated spinal explants

(2016) S. Usmani et al.   Science Advances

A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors

(2016) Hui Xu et al.   Scientific Reports

High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform

(2016) Nienke R. Wevers et al.   Scientific Reports

Brain Tissue Responses to Neural Implants Impact Signal Sensitivity and Intervention Strategies

(2015) Takashi D. Y. Kozai et al.   ACS Chemical Neuroscience

Neural Stimulation and Recording with Bidirectional, Soft Carbon Nanotube Fiber Microelectrodes

(2015) Flavia Vitale et al.   ACS Nano

Nanostructured platinum grass enables superior impedance reduction for neural microelectrodes

(2015) C. Boehler et al.   BIOMATERIALS

Nebulized solvent ablation of aligned PLLA fibers for the study of neurite response to anisotropic-to-isotropic fiber/film transition (AFFT) boundaries in astrocyte–neuron co-cultures

(2015) Jonathan M. Zuidema et al.   BIOMATERIALS

Mechanical failure modes of chronically implanted planar silicon-based neural probes for laminar recording

(2015) Takashi D.Y. Kozai et al.   BIOMATERIALS

Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor

(2015) Jacquelyn A. Brown et al.   Biomicrofluidics

Deep Brain Stimulation in Neurological and Psychiatric Disorders

(2015) Volker A. Coenen et al.   Deutsches Arzteblatt International

Discovery of a novel neuroprotectant, BHDPC, that protects against MPP + /MPTP-induced neuronal death in multiple experimental models

(2015) Cheong-Meng Chong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nanogrooved Surface-Patterns induce cellular organization and axonal outgrowth in neuron-like PC12-Cells

(2015) Alexey Klymov et al.   HEARING RESEARCH

PEDOT–CNT coated electrodes stimulate retinal neurons at low voltage amplitudes and low charge densities

(2015) R Samba et al.   Journal of Neural Engineering

New methods for investigation of neuronal migration in embryonic brain explants

(2015) Flávia C. Nery et al.   JOURNAL OF NEUROSCIENCE METHODS

Magnetoelectric ‘spin’ on stimulating the brain

(2015) Rakesh Guduru et al.   Nanomedicine

A flexible and implantable microelectrode arrays using high-temperature grown vertical carbon nanotubes and a biocompatible polymer substrate

(2015) Wenwen Yi et al.   NANOTECHNOLOGY

Polyurethane/poly(vinyl alcohol) hydrogel coating improves the cytocompatibility of neural electrodes

(2015) YanwenY Duan et al.   Neural Regeneration Research

Organotypic brain slice cultures: A review

(2015) C. Humpel   NEUROSCIENCE

Neuronal-glial populations form functional networks in a biocompatible 3D scaffold

(2015) Imogen Smith et al.   NEUROSCIENCE LETTERS

Deep Brain Stimulation for Movement Disorders

(2015) Maria A. Revell   NURSING CLINICS OF NORTH AMERICA

Wireless magnetothermal deep brain stimulation

(2015) R. Chen et al.   SCIENCE

Extracellular environment contribution to astrogliosis—lessons learned from a tissue engineered 3D model of the glial scar

(2015) Daniela N. Rocha et al.   Frontiers in Cellular Neuroscience

Electrochemical properties of titanium nitride nerve stimulation electrodes: an in vitro and in vivo study

(2015) Suzan Meijs et al.   Frontiers in Neuroscience

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

(2015) Felix Fluri et al.   Jove-Journal of Visualized Experiments

Hyaluronic Acid-Based 3D Culture Model for In Vitro Testing of Electrode Biocompatibility

(2014) Andrea F. Jeffery et al.   BIOMACROMOLECULES

The roles of blood-derived macrophages and resident microglia in the neuroinflammatory response to implanted Intracortical microelectrodes

(2014) Madhumitha Ravikumar et al.   BIOMATERIALS

The effect of inflammatory cell-derived MCP-1 loss on neuronal survival during chronic neuroinflammation

(2014) Andrew J. Sawyer et al.   BIOMATERIALS

Materials considerations of implantable neuroengineering devices for clinical use

(2014) Daniel R. Merrill   CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE

S100β as an early biomarker of excitotoxic damage in spinal cord organotypic cultures

(2014) Graciela L. Mazzone et al.   JOURNAL OF NEUROCHEMISTRY

The role of the surface on microglia function: implications for central nervous system tissue engineering

(2014) L. R. Pires et al.   Journal of the Royal Society Interface

Generation of cerebral organoids from human pluripotent stem cells

(2014) Madeline A Lancaster et al.   Nature Protocols

Fixing problems with cell lines

(2014) Jon R. Lorsch et al.   SCIENCE

Topographical control of cell-cell interaction in C6 glioma by nanodot arrays

(2014) Chia-Hui Lee et al.   Nanoscale Research Letters

Carbon Nanotube Yarn Electrodes for Enhanced Detection of Neurotransmitter Dynamics in Live Brain Tissue

(2013) Andreas C. Schmidt et al.   ACS Nano

Poly(3,4-ethylenedioxythiophene)/multiwall carbon nanotube composite coatings for improving the stability of microelectrodes in neural prostheses applications

(2013) Haihan Zhou et al.   Acta Biomaterialia

The impact of chronic blood–brain barrier breach on intracortical electrode function

(2013) Tarun Saxena et al.   BIOMATERIALS

Antagonism of purinergic signalling improves recovery from traumatic brain injury

(2013) Anthony M. Choo et al.   BRAIN

Neuroprotective Effects of α-Tocotrienol on Kainic Acid-Induced Neurotoxicity in Organotypic Hippocampal Slice Cultures

(2013) Na Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chronic intracortical microelectrode arrays induce non-uniform, depth-related tissue responses

(2013) Andrew J Woolley et al.   Journal of Neural Engineering

Examining the inflammatory response to nanopatterned polydimethylsiloxane using organotypic brain slice methods

(2013) Evon S. Ereifej et al.   JOURNAL OF NEUROSCIENCE METHODS

Nanostructured TiO2 surfaces promote polarized activation of microglia, but not astrocytes, toward a proinflammatory profile

(2013) Silvia De Astis et al.   Nanoscale

Neuroprotection by steroids after neurotrauma in organotypic spinal cord cultures: A key role for progesterone receptors and steroidal modulators of GABAA receptors

(2013) Florencia Labombarda et al.   NEUROPHARMACOLOGY

Modeling nigrostriatal degeneration in organotypic cultures, a new ex vivo model of Parkinson’s disease

(2013) N. Daviaud et al.   NEUROSCIENCE

Nestin-Expressing Stem Cells Promote Nerve Growth in Long-Term 3-Dimensional Gelfoam®-Supported Histoculture

(2013) Sumiyuki Mii et al.   PLoS One

Comparative neuronal differentiation of self-renewing neural progenitor cell lines obtained from human induced pluripotent stem cells

(2013) Chiara Verpelli et al.   Frontiers in Cellular Neuroscience

Carbon nanotube-based multi electrode arrays for neuronal interfacing: progress and prospects

(2013) Lilach Bareket-Keren et al.   Frontiers in Neural Circuits

Dexmedetomidine is neuroprotective in an in vitro model for traumatic brain injury

(2012) Marc Schoeler et al.   BMC Neurology

Nanopatterning effects on astrocyte reactivity

(2012) Evon S. Ereifej et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Design, simulation and experimental validation of a novel flexible neural probe for deep brain stimulation and multichannel recording

(2012) Hsin-Yi Lai et al.   Journal of Neural Engineering

Organotypic Brain Slice Cultures of Adult Transgenic P301S Mice—A Model for Tauopathy Studies

(2012) Agneta Mewes et al.   PLoS One

Cytoprotective effects of growth factors: BDNF more potent than GDNF in an organotypic culture model of Parkinson's disease

(2011) K. Stahl et al.   BRAIN RESEARCH

The development of a rat in vitro model of spinal cord injury demonstrating the additive effects of rho and ROCK inhibitors on neurite outgrowth and myelination

(2011) Stephanie D. Boomkamp et al.   GLIA

Carbon Nanotube Yarns for Deep Brain Stimulation Electrode

(2011) Changqing Jiang et al.   IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING

BV-2 microglial cells sense micro-nanotextured silicon surface topology

(2011) Saydulla Persheyev et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

c-Fos expression after deep brain stimulation of the pedunculopontine tegmental nucleus in the rat 6-hydroxydopamine Parkinson model

(2011) Assel Saryyeva et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Development of a stimuli-responsive polymer nanocomposite toward biologically optimized, MEMS-based neural probes

(2011) A E Hess et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Carbon nanotube composite coating of neural microelectrodes preferentially improves the multiunit signal-to-noise ratio

(2011) Gytis Baranauskas et al.   Journal of Neural Engineering

Mechanically adaptive intracortical implants improve the proximity of neuronal cell bodies

(2011) J P Harris et al.   Journal of Neural Engineering

Organotypic Spinal Cord Slice Culture to Study Neural Stem/Progenitor Cell Microenvironment in the Injured Spinal Cord

(2011) Hyuk Min Kim et al.   Experimental Neurobiology

An organotypic culture model to study nigro-striatal degeneration

(2010) Fabio Cavaliere et al.   JOURNAL OF NEUROSCIENCE METHODS

Biocompatibility Assessment of Insulating Silicone Polymer Coatings Using an in vitro Glial Scar Assay

(2010) Anil Kumar H. Achyuta et al.   MACROMOLECULAR BIOSCIENCE

Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics

(2010) Dae-Hyeong Kim et al.   NATURE MATERIALS

Kainic acid-induced neurodegeneration and activation of inflammatory processes in organotypic hippocampal slice cultures: Treatment with cyclooxygenase-2 inhibitor does not prevent neuronal death

(2010) Juha T. Järvelä et al.   NEUROPHARMACOLOGY

On the nature of biomaterials

(2009) David F. Williams   BIOMATERIALS

Rotenone Induces Cell Death of Cholinergic Neurons in an Organotypic Co-Culture Brain Slice Model

(2009) Celine Ullrich et al.   NEUROCHEMICAL RESEARCH

Delayed treatments for stroke influence neuronal death in rat organotypic slice cultures subjected to oxygen glucose deprivation

(2009) A.A. Hall et al.   NEUROSCIENCE

Neural Stimulation and Recording Electrodes

(2008) Stuart F. Cogan   Annual Review of Biomedical Engineering

On the mechanisms of biocompatibility

(2008) David F. Williams   BIOMATERIALS

Conducting polymers for neural interfaces: Challenges in developing an effective long-term implant

(2008) Rylie A. Green et al.   BIOMATERIALS

Advanced Neurotechnologies for Chronic Neural Interfaces: New Horizons and Clinical Opportunities

(2008) D. R. Kipke et al.   JOURNAL OF NEUROSCIENCE