In Vitro Screening for Seizure Liability Using Microelectrode Array Technology

The emerging role of in vitro electrophysiological methods in CNS safety pharmacology

(2016) Michael V. Accardi et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Safety pharmacology investigations on the nervous system: An industry survey

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A multiplexed assay for determination of neurotoxicant effects on spontaneous network activity and viability from microelectrode arrays

(2015) Kathleen Wallace et al.   NEUROTOXICOLOGY

Freshly frozen E18 rat cortical cells can generate functional neural networks after standard cryopreservation and thawing procedures

(2014) Kim Quasthoff et al.   CYTOTECHNOLOGY

Multi-well microelectrode array recordings detect neuroactivity of ToxCast compounds

(2014) Pablo Valdivia et al.   NEUROTOXICOLOGY

Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection

(2014) Vaishali Bane et al.   Toxins

Advantages of an antagonist: bicuculline and other GABA antagonists

(2013) Graham AR Johnston   BRITISH JOURNAL OF PHARMACOLOGY

Reducing attrition in drug development: smart loading preclinical safety assessment

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Early Activation of Ventral Hippocampus and Subiculum during Spontaneous Seizures in a Rat Model of Temporal Lobe Epilepsy

(2013) I. Toyoda et al.   JOURNAL OF NEUROSCIENCE

Tranexamic acid concentrations associated with human seizures inhibit glycine receptors

(2012) Irene Lecker et al.   JOURNAL OF CLINICAL INVESTIGATION

Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set

(2012) Emma R. McConnell et al.   NEUROTOXICOLOGY

Burst analysis tool for developing neuronal networks exhibiting highly varying action potential dynamics

(2012) Fikret E. Kapucu et al.   Frontiers in Computational Neuroscience

Spiking Patterns and Their Functional Implications in the Antennal Lobe of the Tobacco Hornworm Manduca sexta

(2011) Hong Lei et al.   PLoS One

Interaction between voltage-gated sodium channels and the neurotoxin, tetrodotoxin

(2010) Chong Hyun Lee et al.   Channels

In search of models of pharmacoresistant epilepsy

(2010) Abdul Wahab et al.   EPILEPSIA

Investigating neuronal activity by SPYCODE multi-channel data analyzer

(2010) Luca Leonardo Bologna et al.   NEURAL NETWORKS

Potentiation and inhibition of glycine receptors by tutin

(2010) Jorge Fuentealba et al.   NEUROPHARMACOLOGY

Microelectrode arrays: A physiologically based neurotoxicity testing platform for the 21st century☆

(2010) Andrew F.M. Johnstone et al.   NEUROTOXICOLOGY

Seizure risk associated with neuroactive drugs: Data from the WHO adverse drug reactions database

(2009) Eva Kumlien et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Domoic acid and human exposure risks: A review

(2009) Kathi A. Lefebvre et al.   TOXICON

Self-organization and neuronal avalanches in networks of dissociated cortical neurons

(2008) V. Pasquale et al.   NEUROSCIENCE

An efficient algorithm for continuous time cross correlogram of spike trains

(2007) Il Park et al.   JOURNAL OF NEUROSCIENCE METHODS