Dichloroacetate Stabilizes Mitochondrial Fusion Dynamics in Models of Neurodegeneration
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Title
Dichloroacetate Stabilizes Mitochondrial Fusion Dynamics in Models of Neurodegeneration
Authors
Keywords
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Journal
Frontiers in Molecular Neuroscience
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-09-18
DOI
10.3389/fnmol.2019.00219
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- (2014) Daniel Santos et al. MOLECULAR NEUROBIOLOGY
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