Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase I is essential for cancer cell proliferation independent of β-oxidation

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

(2016) Michael D. Buck et al.   CELL

Short- and medium-chain fatty acids in energy metabolism: the cellular perspective

(2016) Peter Schönfeld et al.   JOURNAL OF LIPID RESEARCH

Structure of mammalian respiratory complex I

(2016) Jiapeng Zhu et al.   NATURE

Lactate metabolism is associated with mammalian mitochondria

(2016) Ying-Jr Chen et al.   Nature Chemical Biology

Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer

(2016) Roman Camarda et al.   NATURE MEDICINE

Fatty acid oxidation is required for the respiration and proliferation of malignant glioma cells

(2016) Hua Lin et al.   NEURO-ONCOLOGY

Altering the Mitochondrial Fatty Acid Synthesis (mtFASII) Pathway Modulates Cellular Metabolic States and Bioactive Lipid Profiles as Revealed by Metabolomic Profiling

(2016) Hayley B. Clay et al.   PLoS One

Fatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancer

(2016) Q Qu et al.   Cell Death & Disease

Carnitine palmitoyl transferase-1A (CPT1A): a new tumor specific target in human breast cancer

(2016) Sabina Pucci et al.   Oncotarget

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells

(2015) Lucas B. Sullivan et al.   CELL

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

(2015) Sandra Schoors et al.   NATURE

X13CMS: Global Tracking of Isotopic Labels in Untargeted Metabolomics

(2014) Xiaojing Huang et al.   ANALYTICAL CHEMISTRY

High grade glioblastoma is associated with aberrant expression of ZFP57, a protein involved in gene imprinting, and of CPT1A and CPT1C that regulate fatty acid metabolism

(2014) Alessandra Cirillo et al.   CANCER BIOLOGY & THERAPY

OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand

(2014) D. A. Patten et al.   EMBO JOURNAL

Cardiolipin remodeling: a regulatory hub for modulating cardiolipin metabolism and function

(2014) Cunqi Ye et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Lipid Catabolism via CPT1 as a Therapeutic Target for Prostate Cancer

(2014) I. R. Schlaepfer et al.   MOLECULAR CANCER THERAPEUTICS

The mitochondrial fatty acid synthesis (mtFASII) pathway is capable of mediating nuclear-mitochondrial cross talk through the PPAR system of transcriptional activation

(2013) Angelika Parl et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

(2013) Sara Cogliati et al.   CELL

Deacylation on the matrix side of the mitochondrial inner membrane regulates cardiolipin remodeling

(2013) Matthew G. Baile et al.   MOLECULAR BIOLOGY OF THE CELL

Iron metabolism in the CNS: implications for neurodegenerative diseases

(2013) Tracey A. Rouault   NATURE REVIEWS NEUROSCIENCE

Mitochondrial lipid trafficking

(2013) Takashi Tatsuta et al.   TRENDS IN CELL BIOLOGY

Activation of Mitochondrial Calcium-independent Phospholipase A2γ (iPLA2γ) by Divalent Cations Mediating Arachidonate Release and Production of Downstream Eicosanoids

(2012) Sung Ho Moon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

(2012) Sang-Min Jeon et al.   NATURE

Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells

(2012) Marco Spinazzi et al.   Nature Protocols

Inhibition of Fatty Acid Metabolism Reduces Human Myeloma Cells Proliferation

(2012) José Manuel Tirado-Vélez et al.   PLoS One

Compromised Mitochondrial Fatty Acid Synthesis in Transgenic Mice Results in Defective Protein Lipoylation and Energy Disequilibrium

(2012) Stuart Smith et al.   PLoS One

Human Trifunctional Protein Alpha Links Cardiolipin Remodeling to Beta-Oxidation

(2012) William A. Taylor et al.   PLoS One

Mitochondrial membrane potential probes and the proton gradient: a practical usage guide

(2011) Seth W. Perry et al.   BIOTECHNIQUES

Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress

(2011) K. Zaugg et al.   GENES & DEVELOPMENT

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

(2011) Christian M. Metallo et al.   NATURE

Mitochondrial Structure and Function Are Disrupted by Standard Isolation Methods

(2011) Martin Picard et al.   PLoS One

Current understanding of fatty acid biosynthesis and the acyl carrier protein

(2010) David I. Chan et al.   BIOCHEMICAL JOURNAL

Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells

(2010) Lisa S. Pike et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Down-regulation of Mitochondrial Acyl Carrier Protein in Mammalian Cells Compromises Protein Lipoylation and Respiratory Complex I and Results in Cell Death

(2009) Dejiang Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

(2009) Ismael Samudio et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulatory enzymes of mitochondrial β-oxidation as targets for treatment of the metabolic syndrome

(2009) M. Schreurs et al.   Obesity Reviews

Mitochondrial fatty acid synthesis – An adopted set of enzymes making a pathway of major importance for the cellular metabolism

(2009) J. Kalervo Hiltunen et al.   PROGRESS IN LIPID RESEARCH

CPT1c Is Localized in Endoplasmic Reticulum of Neurons and Has Carnitine Palmitoyltransferase Activity

(2008) Adriana Y. Sierra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Fatty Acid Synthesis Type II: More than Just Fatty Acids

(2008) J. Kalervo Hiltunen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial fatty acid synthesis is required for normal mitochondrial morphology and function in Trypanosoma brucei

(2008) Jennifer L. Guler et al.   MOLECULAR MICROBIOLOGY

Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue

(2007) Morris A. Kostiuk et al.   FASEB JOURNAL