High-Fat Diet Increases Amylin Accumulation in the Hippocampus and Accelerates Brain Aging in hIAPP Transgenic Mice

Cerebral glucose metabolism in idiopathic REM sleep behavior disorder is different from tau-related and α-synuclein-related neurodegenerative disorders: A brain [18F]FDG PET study

(2019) Claudio Liguori et al.   PARKINSONISM & RELATED DISORDERS

Molecular Mechanisms Underpinning Microparticle-Mediated Cellular Injury in Cardiovascular Complications Associated with Diabetes

(2019) Tarek Benameur et al.   Oxidative Medicine and Cellular Longevity

Type 2 diabetes mellitus, brain atrophy, and cognitive decline

(2019) Chris Moran et al.   NEUROLOGY

Role of growth factors and cytokines in diabetic foot ulcer healing: A detailed review

(2019) Mohammad Zubair et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Role of microglia-neuron interactions in diabetic encephalopathy

(2018) Yuan Liu et al.   AGEING RESEARCH REVIEWS

Evidence for brain glucose dysregulation in Alzheimer's disease

(2018) Yang An et al.   Alzheimers & Dementia

Impact of estrogens and estrogen receptor-α in brain lipid metabolism

(2018) Eugenia Morselli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Triglyceride-mediated influence of serum angiopoietin-like protein 8 on subclinical atherosclerosis in type 2 diabetic patients: results from the GDMD study in China

(2018) Tianpeng Zheng et al.   Cardiovascular Diabetology

Metabolic fate of glucose in the brain of APP/PS1 transgenic mice at 10 months of age: a 13C NMR metabolomic study

(2018) Qi Zhou et al.   METABOLIC BRAIN DISEASE

Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease

(2018) Miren Ettcheto et al.   MOLECULAR NEUROBIOLOGY

Time dependence of NMR observables reveals salient differences in the accumulation of early aggregated species between human islet amyloid polypeptide and amyloid-β

(2018) Anaïs R. F. Hoffmann et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Alzheimer's disease and Type 2 Diabetes mellitus are distinct diseases with potential overlapping metabolic dysfunction upstream of observed cognitive decline

(2018) Yevgen Chornenkyy et al.   BRAIN PATHOLOGY

Global View on Alzheimer’s Disease and Diabetes Mellitus: Threats, Risks and Treatment

(2018) Blanka Klimova et al.   Current Alzheimer Research

A fucoidan from sea cucumber Pearsonothuria graeffei with well-repeated structure alleviates gut microbiota dysbiosis and metabolic syndromes in HFD-fed mice

(2018) Shan Li et al.   Food & Function

Reduced Regional Cerebral Blood Flow Relates to Poorer Cognition in Older Adults With Type 2 Diabetes

(2018) Katherine J. Bangen et al.   Frontiers in Aging Neuroscience

Short-term high-fat diet exacerbates insulin resistance and glycolipid metabolism disorders in young obese men with hyperlipidemia, as determined by metabolomics analysis using ultra-HPLC-quadrupole time-of-flight mass spectrometry

(2018) Rennan Feng et al.   Journal of Diabetes

Comorbidity Analysis between Alzheimer’s Disease and Type 2 Diabetes Mellitus (T2DM) Based on Shared Pathways and the Role of T2DM Drugs

(2017) Reagon Karki et al.   JOURNAL OF ALZHEIMERS DISEASE

Pancreas Atrophy and Islet Amyloid Deposition in Patients With Elderly-Onset Type 2 Diabetes

(2017) An Xin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Islet amyloid polypeptide response to maximal hyperglycemia and arginine is altered in impaired glucose tolerance and type 2 diabetes mellitus

(2016) Rodolfo Guardado-Mendoza et al.   ACTA DIABETOLOGICA

Estrogen and insulin transport through the blood-brain barrier

(2016) Aaron A. May et al.   PHYSIOLOGY & BEHAVIOR

Diabetic retinopathy

(2016) Tien Y. Wong et al.   Nature Reviews Disease Primers

In Vivo Seeding and Cross-Seeding of Localized Amyloidosis

(2015) Marie E. Oskarsson et al.   AMERICAN JOURNAL OF PATHOLOGY

Islet amyloid polypeptide exerts a novel autocrine action in β-cell signaling and proliferation

(2015) Montse Visa et al.   FASEB JOURNAL

Type 2 diabetes mellitus

(2015) Ralph A. DeFronzo et al.   Nature Reviews Disease Primers

The regulation of glucose metabolism: implications and considerations for the assessment of glucose homeostasis in rodents

(2014) Greg M. Kowalski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Amyloid aggregation and deposition of human islet amyloid polypeptide at membrane interfaces

(2014) Kenji Sasahara et al.   FEBS Journal

Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin

(2014) Sarah Srodulski et al.   Molecular Neurodegeneration

Amylin deposition in the brain: A second amyloid in Alzheimer disease?

(2013) Kaleena Jackson et al.   ANNALS OF NEUROLOGY

Pinpointing Proline Substitution to be Responsible for the Loss of Amyloidogenesis in IAPP

(2013) Sandipan Chakraborty et al.   Chemical Biology & Drug Design

Mechanisms of Diabetic Complications

(2013) Josephine M. Forbes et al.   PHYSIOLOGICAL REVIEWS

The Effect of Aβ on IAPP Aggregation in the Presence of an Isolated β-Cell Membrane

(2012) Janine Seeliger et al.   JOURNAL OF MOLECULAR BIOLOGY

Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro

(2011) Ganta V Chaitanya et al.   Journal of Neuroinflammation

Reverse engineering an amyloid aggregation pathway with dimensional analysis and scaling

(2011) J Bailey et al.   PHYSICAL BIOLOGY

Identification of Hot Regions of the Aβ-IAPP Interaction Interface as High-Affinity Binding Sites in both Cross- and Self-Association

(2010) Erika Andreetto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interaction of hIAPP with Model Raft Membranes and Pancreatic β-Cells: Cytotoxicity of hIAPP Oligomers

(2010) Katrin Weise et al.   CHEMBIOCHEM

Fatty acids induce amylin expression and secretion by pancreatic β-cells

(2009) Dongfei Qi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pancreatic islet amyloidosis,  -cell apoptosis, and  -cell proliferation are determinants of islet remodeling in type-2 diabetic baboons

(2009) R. Guardado-Mendoza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent Insights in Islet Amyloid Polypeptide-Induced Membrane Disruption and Its Role inβ-Cell Death in Type 2 Diabetes Mellitus

(2008) Lucie Khemtémourian et al.   Experimental Diabetes Research

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE