A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission

(2019) Heather C. Rice et al.   SCIENCE

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

(2018) Michael J. Gandal et al.   SCIENCE

An accurate and robust imputation method scImpute for single-cell RNA-seq data

(2018) Wei Vivian Li et al.   Nature Communications

A transcriptomic atlas of aged human microglia

(2018) Marta Olah et al.   Nature Communications

Brain Cell Type Specific Gene Expression and Co-expression Network Architectures

(2018) Andrew T. McKenzie et al.   Scientific Reports

Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models

(2018) Brad A. Friedman et al.   Cell Reports

Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure

(2018) Zeran Li et al.   Genome Medicine

Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain

(2018) Arpiar Saunders et al.   CELL

Alzheimer's Disease: The Downside of a Highly Evolved Parietal Lobe?

(2018) Emiliano Bruner et al.   JOURNAL OF ALZHEIMERS DISEASE

Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes

(2018) Kevin W. Kelley et al.   NATURE NEUROSCIENCE

Shared and distinct transcriptomic cell types across neocortical areas

(2018) Bosiljka Tasic et al.   NATURE

Single-nucleus and single-cell transcriptomes compared in matched cortical cell types

(2018) Trygve E. Bakken et al.   PLoS One

Comprehensive functional genomic resource and integrative model for the human brain

(2018) Daifeng Wang et al.   SCIENCE

Dissecting Cell-Type Composition and Activity-Dependent Transcriptional State in Mammalian Brains by Massively Parallel Single-Nucleus RNA-Seq

(2017) Peng Hu et al.   MOLECULAR CELL

Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain

(2017) Blue B Lake et al.   NATURE BIOTECHNOLOGY

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity

(2017) Renchao Chen et al.   Cell Reports

TSCAN: Pseudo-time reconstruction and evaluation in single-cell RNA-seq analysis

(2016) Zhicheng Ji et al.   NUCLEIC ACIDS RESEARCH

Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

(2016) B. B. Lake et al.   SCIENCE

Identification of cell types from single-cell transcriptomes using a novel clustering method

(2015) Chen Xu et al.   BIOINFORMATICS

RNA-seq based transcriptomic analysis of single bacterial cells

(2015) Jiangxin Wang et al.   Integrative Biology

The glia/neuron ratio: How it varies uniformly across brain structures and species and what that means for brain physiology and evolution

(2014) Suzana Herculano-Houzel   GLIA

Developmental regulation of human cortex transcription and its clinical relevance at single base resolution

(2014) Andrew E Jaffe et al.   NATURE NEUROSCIENCE

RNA-sequencing from single nuclei

(2013) R. V. Grindberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

Parietal cortex matters in Alzheimer's disease: An overview of structural, functional and metabolic findings

(2011) Heidi I.L. Jacobs et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Novel Research Horizons for Presenilins and γ-Secretases in Cell Biology and Disease

(2010) Bart De Strooper et al.   Annual Review of Cell and Developmental Biology

Functional organization of the transcriptome in human brain

(2008) Michael C Oldham et al.   NATURE NEUROSCIENCE

The parietal cortex and episodic memory: an attentional account

(2008) Roberto Cabeza et al.   NATURE REVIEWS NEUROSCIENCE