Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure
Authors
Keywords
Digital deconvolution, Alzheimer’s disease, Brain cellular composition, Bulk RNA-sequencing, Autosomal dominant AD, <em class=EmphasisTypeItalic >TREM2</em>
Journal
Genome Medicine
Volume 10, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-06-06
DOI
10.1186/s13073-018-0551-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Massively parallel single-nucleus RNA-seq with DroNc-seq
- (2017) Naomi Habib et al. NATURE METHODS
- Salmon provides fast and bias-aware quantification of transcript expression
- (2017) Rob Patro et al. NATURE METHODS
- Elucidating the Role of TREM2 in Alzheimer’s Disease
- (2017) Jason D. Ulrich et al. NEURON
- TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy
- (2017) Cheryl E. G. Leyns et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Directed Differentiation of Human Pluripotent Stem Cells to Microglia
- (2017) Panagiotis Douvaras et al. Stem Cell Reports
- SORL1 variants across Alzheimer’s disease European American cohorts
- (2016) Maria Victoria Fernández et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
- (2016) Yaming Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Neurological manifestations of autosomal dominant familial Alzheimer’s disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)
- (2016) Mengxuan Tang et al. LANCET NEUROLOGY
- Clinical phenotype and genetic associations in autosomal dominant familial Alzheimer’s disease: a case series
- (2016) Natalie S Ryan et al. LANCET NEUROLOGY
- Genetic variants in Alzheimer disease — molecular and brain network approaches
- (2016) Chris Gaiteri et al. Nature Reviews Neurology
- Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
- (2016) Ye Zhang et al. NEURON
- Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses
- (2016) Karpagam Srinivasan et al. Nature Communications
- Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases
- (2016) Mariet Allen et al. Scientific Data
- CellCODE: a robust latent variable approach to differential expression analysis for heterogeneous cell populations
- (2015) Maria Chikina et al. BIOINFORMATICS
- Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease
- (2015) Stacy Steinberg et al. NATURE GENETICS
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- CD33 modulates TREM2: convergence of Alzheimer loci
- (2015) Gail Chan et al. NATURE NEUROSCIENCE
- Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders
- (2015) Neelroop N. Parikshak et al. NATURE REVIEWS GENETICS
- Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European–Americans
- (2015) Jorge L. Del-Aguila et al. Alzheimers Research & Therapy
- Neurostereology protocol for unbiased quantification of neuronal injury and neurodegeneration
- (2015) Victoria M. Golub et al. Frontiers in Aging Neuroscience
- Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
- (2015) Inge R Holtman et al. Acta Neuropathologica Communications
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases
- (2014) M. Narayanan et al. Molecular Systems Biology
- Cell type–specific mRNA purification by translating ribosome affinity purification (TRAP)
- (2014) Myriam Heiman et al. Nature Protocols
- CORTECON: A Temporal Transcriptome Analysis of In Vitro Human Cerebral Cortex Development from Human Embryonic Stem Cells
- (2014) Joyce van de Leemput et al. NEURON
- Is pathological aging a successful resistance against amyloid-beta or preclinical Alzheimer’s disease?
- (2014) Melissa E Murray et al. Alzheimers Research & Therapy
- CellMix: a comprehensive toolbox for gene expression deconvolution
- (2013) R. Gaujoux et al. BIOINFORMATICS
- Digital sorting of complex tissues for cell type-specific gene expression profiles
- (2013) Yi Zhong et al. BMC BIOINFORMATICS
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
- (2013) Bin Zhang et al. CELL
- Computational deconvolution: extracting cell type-specific information from heterogeneous samples
- (2013) Shai S Shen-Orr et al. CURRENT OPINION IN IMMUNOLOGY
- Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease
- (2013) Carlos Cruchaga et al. NATURE
- Neuroinflammation and Neuronal Loss Precede Aβ Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s Disease
- (2013) Amanda L. Wright et al. PLoS One
- Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification
- (2013) P. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuropathological Alterations in Alzheimer Disease
- (2013) A. Serrano-Pozo et al. Cold Spring Harbor Perspectives in Medicine
- Genes and pathways underlying regional and cell type changes in Alzheimer's disease
- (2013) Jeremy A Miller et al. Genome Medicine
- Effectively Identifying eQTLs from Multiple Tissues by Combining Mixed Model and Meta-analytic Approaches
- (2013) Jae Hoon Sul et al. PLoS Genetics
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Semi-supervised Nonnegative Matrix Factorization for gene expression deconvolution: A case study
- (2011) Renaud Gaujoux et al. INFECTION GENETICS AND EVOLUTION
- Integrative genomics viewer
- (2011) James T Robinson et al. NATURE BIOTECHNOLOGY
- Population-specific expression analysis (PSEA) reveals molecular changes in diseased brain
- (2011) Alexandre Kuhn et al. NATURE METHODS
- Optimal Deconvolution of Transcriptional Profiling Data Using Quadratic Programming with Application to Complex Clinical Blood Samples
- (2011) Ting Gong et al. PLoS One
- Human apoE Isoforms Differentially Regulate Brain Amyloid- Peptide Clearance
- (2011) J. M. Castellano et al. Science Translational Medicine
- Novel Research Horizons for Presenilins and γ-Secretases in Cell Biology and Disease
- (2010) Bart De Strooper et al. Annual Review of Cell and Developmental Biology
- Atrophy in the parahippocampal gyrus as an early biomarker of Alzheimer’s disease
- (2010) C. Echávarri et al. Brain Structure & Function
- The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
- (2010) A. McKenna et al. GENOME RESEARCH
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- The Role of Apolipoprotein E in Alzheimer's Disease
- (2009) Jungsu Kim et al. NEURON
- Deconvolution of Blood Microarray Data Identifies Cellular Activation Patterns in Systemic Lupus Erythematosus
- (2009) Alexander R. Abbas et al. PLoS One
- A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
- (2008) J. D. Cahoy et al. JOURNAL OF NEUROSCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More