Autophagy inhibition-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis

FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axis

(2019) Ran Wei et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells

(2019) Yihua Wang et al.   Autophagy

Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts

(2018) Saeid Ghavami et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Autophagy in health and disease: A comprehensive review

(2018) Sarbari Saha et al.   BIOMEDICINE & PHARMACOTHERAPY

Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis

(2018) Mark G Jones et al.   eLife

Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline

(2018) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Paracrine signalling during ZEB1-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in lung fibrosis

(2018) Liudi Yao et al.   CELL DEATH AND DIFFERENTIATION

Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA

(2017) Matthew A. Coelho et al.   IMMUNITY

Idiopathic pulmonary fibrosis

(2017) Luca Richeldi et al.   LANCET

The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis

(2017) Franco Conforti et al.   Oncotarget

Inhibition of ZEB1 leads to inversion of metastatic characteristics and restoration of paclitaxel sensitivity of chronic chemoresistant ovarian carcinoma cells

(2017) Jun Sakata et al.   Oncotarget

mTORC1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts

(2016) Yair Romero et al.   AGING CELL

Novel Mechanisms for the Antifibrotic Action of Nintedanib

(2016) Sunad Rangarajan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mammalian Autophagy: How Does It Work?

(2016) Carla F. Bento et al.   Annual Review of Biochemistry

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Epithelial to mesenchymal transition-related proteins ZEB1, β-catenin and β-tubulin-III in idiopathic pulmonary fibrosis

(2016) Marco Chilosi et al.   MODERN PATHOLOGY

Autophagy and epithelial–mesenchymal transition: an intricate interplay in cancer

(2016) Mila Gugnoni et al.   Cell Death & Disease

Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review

(2015) John Hutchinson et al.   EUROPEAN RESPIRATORY JOURNAL

Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells

(2015) Myriam Catalano et al.   Molecular Oncology

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

(2015) M Teresa Grande et al.   NATURE MEDICINE

Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis

(2015) Sara Lovisa et al.   NATURE MEDICINE

The Essential Autophagy GeneATG7Modulates Organ Fibrosis via Regulation of Endothelial-to-Mesenchymal Transition

(2014) Krishna K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibrosis: ultimate and proximate causes

(2014) Victor J. Thannickal et al.   JOURNAL OF CLINICAL INVESTIGATION

PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis

(2014) Marta Bueno et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Clinical significance of mTOR, ZEB1, ROCK1 expression in lung tissues of pulmonary fibrosis patients

(2014) Jong Sun Park et al.   BMC Pulmonary Medicine

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis

(2013) Tasha E Fingerlin et al.   NATURE GENETICS

Coordinate Direct Input of Both KRAS and IGF1 Receptor to Activation of PI3 kinase in KRAS -Mutant Lung Cancer

(2013) Miriam Molina-Arcas et al.   Cancer Discovery

Insufficient autophagy in idiopathic pulmonary fibrosis

(2012) Jun Araya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Autophagy in Idiopathic Pulmonary Fibrosis

(2012) Avignat S. Patel et al.   PLoS One

TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment

(2011) Amber L. Degryse et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis

(2011) Cecilia Marmai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease

(2011) M. Angela Nieto   Annual Review of Cell and Developmental Biology

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Control of autophagy as a therapy for neurodegenerative disease

(2011) Harry Harris et al.   Nature Reviews Neurology

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells

(2010) Shunsuke Minagawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

p62, an autophagy hero or culprit?

(2010) Tor Erik Rusten et al.   NATURE CELL BIOLOGY

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

(2009) Benjamin D. Humphreys et al.   AMERICAN JOURNAL OF PATHOLOGY

Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis

(2009) Harikrishna Tanjore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Epithelial–mesenchymal transition in human lungs with usual interstitial pneumonia: Quantitative immunohistochemistry

(2009) Taishi Harada et al.   PATHOLOGY INTERNATIONAL

SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis

(2009) A Jayachandran et al.   THORAX

Short telomeres are a risk factor for idiopathic pulmonary fibrosis

(2008) J. K. Alder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA